Methyl Folate 400 mcg 5-MTHF

Vitamins

Brand: Natural Nutra

Tablet or PillVitaminOn Market
Click to view full label

Net Contents

90 Vegan Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

90

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

Not specified

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

3Dietary Attributes

Label states: Vegan, Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Egg
  • Fish
  • Shellfish
  • Tree Nuts
  • Peanut
  • Soy

Free From

  • Wheat
  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Folate667 mcg DFE167%
Quatrefolic 5-Methyl-tetrahydrofolate Glucosamine800 mcg
5-MTHF400 mcg

Not Present

Other Ingredients

CelluloseSilicaStearic AcidCalcium Stearate

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Use: Take one tablet daily with or without food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: Children

Keep out of reach of children.

Formulation

Formulation re: Does NOT Contain

Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.

Formulation re: Vegetarian/Vegan

Suitable for vegans.

Formulation re: Other

Unlike folic acid, Quatrefolic 5-Methylfolate is the biologically active form of folate. Methylfolate is required to support cardiovascular and cognitive health, as well as the production of new cells and maintain healthy homocysteine levels. Due to the combination of certain metabolic mutations, poor detoxification, increased stressors and insufficient absorption, our ability to transform folic acid into the active folate form may be inadequate. Quatrefolic 5-Methylfolate is bound to a glucosamine salt, which can enhance absorption.

Formulation re: Other

Purity + potency guaranteed

Formulation re: Other

Supports cardiovascular, brain, and cellular health

Formulation re: Vegetarian/Vegan

Vegan

Formulation re: Does NOT Contain

Gluten free

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Brand IP Statement(s) re: (c), (TM), (SM)

Quatrefolic is a registered trademark of Gnosis S.P.A. Protected by U.S. Patent # 7,947,662.

General Statements: All Other Content

To report a serious adverse event, call 1-888-710-0006

Manufacturer & Distributor

Distributor

Hurd Dynamics LLC, DBA Natural Nutra

Tampa, FL, 33615

1-888-710-0006

Market Reference

$4.51 – $97.00· 40 listings
  • Natural Methyl Folate

    Natural Nutra
    $22.95
  • Nutri Methyl Folate 15 mg 120 Vegan Tablets

    CVS Pharmacy4.7(51)
    $32.49
  • Thorne Research 5-MTHF 5mg 60 Capsules

    Target4.8(506)
    $68.00
  • 365 by Whole Foods Market Methyl Folate 100 Count

    Whole Foods Market
    $9.79
  • Methyl Folate 400mcg

    Walmart - Carlyle Nutritionals, LLC
    $9.59
  • Sprouts Methyl Folate 400 mcg 5-MTHF

    Sprouts
    $15.99
  • Jarrow Formulas Methyl Folate

    Walsh Natural Health4.8(12000)
    $11.99
  • Methyl Folate 400 mcg 5-MTHF

    My Nature's Delight
    $26.99

Where to Buy Locally

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Research & Studies

  • Folic acid and diseases-supplement it or not?

    SC Liew - Revista da Associacao Medica Brasileira, 2016 - SciELO Brasil

    … A double blinded, placebo-controlled study on postmenopausal women who received 5-MTHF (folate/prefolic) yielded a positive correlation between the administration of folate and the …

    2016132 citations
  • Micronutrient bioavailability: Concepts, influencing factors, and strategies for improvement

    JD Richards, H Cori, M Rahn, K Finn, J Bárcena… - Frontiers in …, 2025 - frontiersin.org

    … Combining methylfolate with folic acid may be advantageous. In women of … 400 mcg of folic acid or the equimolar dose of methylfolate (416 mcg) to reach the protective blood folate …

    202518 citations
  • The role of folic acid in DNA methylation and breast cancer

    SR de la Torre Guzmán, B Pelayo-Chávez… - … Journal for Vitamin …, 2025 - imrpress.com

    … tetrahydrofolate (THF) and 5-MTHF, which is the primary … 5-MTHF (5-CH2-THF) by the enzyme methylene tetrahydrofolate reductase (MTHFR) in a process requiring riboflavin. 5-MTHF …

    20253 citations
  • Folate, folic acid and 5-methyltetrahydrofolate are not the same thing

    F Scaglione, G Panzavolta - Xenobiotica, 2014 - Taylor & Francis

    … the use of [6S]-5-MTHF as an effective and safe alternative to synthetic folic acid. Fohr et al. (… amounts of folic acid and [6R,S]-5-MTHF were administered to 160 healthy women of child-…

    2014482 citations
  • Supplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review

    ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com

    … with 400 µg of FA or equimolar doses of 5-MTHF achieved … erythrocyte folate than those receiving half the dose of 5-MTHF… 5-MTHF group achieved somewhat higher erythrocyte folate …

    202426 citations
  • Folic acid, folinic acid, 5 methyl tetrahydrofolate supplementation for mutations that affect epigenesis through the folate and one-carbon cycles

    Y Menezo, K Elder, A Clement, P Clement - Biomolecules, 2022 - mdpi.com

    … , nutritional supplementation with 5-MTHF can effectively improve folate biomarkers in … 5-MTHF can provide a solution for problems related to folate cycle metabolism [51,54]; 5-MTHF …

    2022248 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-04-22. DSLD Label ID: 246996. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.