Brand: Natural Factors

Tablet or PillNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

30 Enteric Coated Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 68958 02707 4

Product Version

R6

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Wheat
  • Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1–2 per day

IngredientAmount Per Serving
S-Adenosyl-L-Methionine ion(SAMe Disulfate Tosylate)200 mg

Not Present

Other Ingredients

CelluloseMannitolEnteric CoatingGlyceryl BehenateMagnesium StearateSilica

Target Groups

Adult (18 - 50 Years)Dairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Usage: 1 tablet on an empty stomach, 2 times per day for 3 weeks; then 1 tablet per day thereafter, or as directed by a health professional.

Warnings & Precautions

Precautions re: Children

Keep out of reach of children.

Precautions re: Pregnant or Nursing or Prescription Medications

CAUTION: Individuals who are using prescription anti-depressants or who suffer from bi-polar disorder should not use this product unless under the supervision of a health professional.

Precautions re: All Other

Sealed for your protection. Do not use if seal is broken.

Storage

Storage

For optimum freshness, refrigerate after opening.

Formulation

Formulation re: Does NOT Contain

Contains no artificial preservatives, color or sweeteners; no corn, dairy, soy, starch, wheat or yeast.

FDA Statements

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Other Label Statements

General Statements: All Other Content

Clinical research shows that SAMe elevates mood and has a positive effect on behavior. It also maintains cartilage health and contributes to the production of joint supporting compounds such as Glucosamine and Chondroitin. Natural Factors SAMe is enteric coated for maximum bioavailiabilty. All Natural Factors products are manufactured in accordance with the Government of Canada's Good Manufacturing Practices (GMP), among the highest standards in the world.

General Statements: All Other Content

PRODUCT OF ITALY

Seals/Symbols

(recycle) Recyclable container and label.

Seals/Symbols

Purity & Potency Guaranteed

General Statements: All Other Content

JOINT & MOOD SUPPORT*

General: Product/Version Code

R6

General Statements: All Other Content

Iso Active

Manufacturer & Distributor

Manufacturer

Natural Factors Canada

Distributor

Natural Factors

1111 - 80th St. SW, Ste 100, Everett, WA, 98203, USA

Market Reference

$9.78 – $102.54· 40 listings
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  • Metabolic Maintenance SAMe + CoFactors 200 mg

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Where to Buy Locally

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Research & Studies

  • Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate …

    H Ullah, A Di Minno, C Esposito, HR El-Seedi… - Biomedicine & …, 2022 - Elsevier

    … of a food supplement based on a combination of S-adenosyl methionine (SAMe, 200 mg/day) … In conclusion, the daily intake of the food supplement based on SAMe and probiotic strains …

    202276 citations
  • S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]

    WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer

    … On most functional health measures both groups showed a notable improvement from … -Methionine (SAMe) used in this study was enteric coated 200 mg tablets from 400 mg S-Adenosyl…

    2004213 citations
  • Herbs and natural supplements, volume 2: An evidence-based guide

    L Braun, M Cohen - 2014 - books.google.com

    … herbal and nutritional supplements, and informed advice from their healthcare practitioner is … in the liver: 200 mg/kg of A. vasica was shown to be comparable to 25 mg/kg of silymarin. In …

    2014572 citations
  • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial

    Heart Protection Study Collaborative Group - The Lancet, 2002 - Elsevier

    … , or diabetes were randomly allocated to receive antioxidant vitamin supplementation (600 mg vitamin E, 250 mg vitamin C, and 20 mg β-carotene daily) or matching placebo. Intention-…

    20021,649 citations
  • Dietary supplements and natural products as psychotherapeutic agents

    A Fugh-Berman, JM Cott - Biopsychosocial Science and Medicine, 1999 - journals.lww.com

    … On examination later the same day, her vital signs and results of physical examination, … healthy volunteers, a kava extract (200 mg) was compared with a high dose of oxazepam (75 mg) …

    1999229 citations
  • Botanical medicines: the desk reference for major herbal supplements

    DJ McKenna, K Jones, K Hughes, VM Tyler - 2012 - books.google.com

    … of plants in health care. Kerry has worked with natural product companies throughout the … Risk factors with a neonate and a toddler are not the same. The blood:breast barrier acts …

    2012247 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-06-01. DSLD Label ID: 8880. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.