SAMe 200 mg®
Non-Nutrient / Non-BotanicalBrand: Natural Factors
Net Contents
60 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 68958 02708 1
Product Version
R2
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Egg
- Fish
- Shellfish
- Tree Nuts
- Wheat
- Soy
- Gluten
Free From
- Milk
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 2 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAMe | 200 mg | — |
| S-Adenosyl-L-Methionine Tosylate Disulfate | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested usage: 1 tablet on an empty stomach, 2 times per day for 3 weeks; then 1 tablet per day thereafter, or as directed by a health professional.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.
Precautions re: Children
Keep out of the reach of children.
Precautions re: All Other
Sealed for your protection. Do not use if seal is broken.
Storage
Storage
For freshness, store in a cool, dry place. For optimum freshness, refrigerate after opening.
Formulation
Formulation re: Does NOT Contain
NON-GMO
Formulation re: Does NOT Contain
Contains no artificial colors, preservatives or sweeteners; no dairy, sugar, wheat, gluten, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans.
FDA Statements
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
isura
General Statements: All Other Content
MASS SPEC Documentation Lab Tested
General Statements: All Other Content
Clinical research shows that SAMe elevates mood and has a positive effect on behavior.* It also maintains cartilage health and contributes to the production of joint supporting compounds such as glucosamine and chondroitin.* Natural Factors SAMe is enteric coated for maximum bioavailability.
General Statements: All Other Content
Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.
General Statements: All Other Content
PRODUCT OF U.S.A.
Seals/Symbols
Purity&Potency Guaranteed
General Statements: All Other Content
Recyclable container and label.
General Statements: All Other Content
Joint and mood support
General: Product/Version Code
R2
Manufacturer & Distributor
Manufacturer
Natural Factors Canada
Distributor
Natural Factors
14224 167th Avenue SE, Monroe, WA, 98272
Market Reference
Natural Factors SAMe 200 mg
iHerb4.8(144)$34.97
Natural Factors SAMe
Mothers Market & Kitchen4.8(144)$49.99
Natural Factors Mixed Vitamin E
Vitacost.com4.8(2500)$11.17
Nature Made SAM-e Complete 400 mg
Walmart - Health4life4.5(45)$46.12
SAMe 200mg 60 Tablets
Bestvite4.7(159)$20.99
Natural Factors Magnesium Bisglycinate Pure 200mg 120 Veggie Caps
vitamin360.com4.6(61)$10.99Lowest
Natural Factors Magnesium Bisglycinate 200 mg
PureFormulas.com4.8(2400)$13.97
Natural Factors Alphalipoic Acid mg
iHerb4.8(332)$12.57
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Primal Nutrition
4.7 (75)Vitamin & supplements store
8114 Roosevelt Blvd, Philadelphia, PA 19152
The Vitamin Shoppe
4.6 (120)Vitamin & supplements store
2383 Cottman Ave Suite 38B, Philadelphia, PA 19149
The Vitamin Shoppe
4.3 (168)Vitamin & supplements store
1701 Chestnut St, Philadelphia, PA 19103
The Vitamin Shoppe
4.4 (88)Vitamin & supplements store
2010 Marlton Pike H, Cherry Hill Township, NJ 08002
The Vitamin Shoppe
4.4 (181)Vitamin & supplements store
1817 Old York Rd, Abington, PA 19001
The Vitamin Shoppe
4.3 (71)Vitamin & supplements store
1490 Nixon Dr, Mt Laurel Township, NJ 08054
Research & Studies
Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate …
H Ullah, A Di Minno, C Esposito, HR El-Seedi… - Biomedicine & …, 2022 - Elsevier
… of a food supplement based on a combination of S-adenosyl methionine (SAMe, 200 mg/day) … In conclusion, the daily intake of the food supplement based on SAMe and probiotic strains …
202275 citationsS-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]
WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer
… On most functional health measures both groups showed a notable improvement from … -Methionine (SAMe) used in this study was enteric coated 200 mg tablets from 400 mg S-Adenosyl…
2004213 citationsHerbs and natural supplements, volume 2: An evidence-based guide
L Braun, M Cohen - 2014 - books.google.com
… herbal and nutritional supplements, and informed advice from their healthcare practitioner is … in the liver: 200 mg/kg of A. vasica was shown to be comparable to 25 mg/kg of silymarin. In …
2014569 citationsMRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial
Heart Protection Study Collaborative Group - The Lancet, 2002 - Elsevier
… , or diabetes were randomly allocated to receive antioxidant vitamin supplementation (600 mg vitamin E, 250 mg vitamin C, and 20 mg β-carotene daily) or matching placebo. Intention-…
20021,648 citationsDietary supplements and natural products as psychotherapeutic agents
A Fugh-Berman, JM Cott - Biopsychosocial Science and Medicine, 1999 - journals.lww.com
… On examination later the same day, her vital signs and results of physical examination, … healthy volunteers, a kava extract (200 mg) was compared with a high dose of oxazepam (75 mg) …
1999229 citationsBotanical medicines: the desk reference for major herbal supplements
DJ McKenna, K Jones, K Hughes, VM Tyler - 2012 - books.google.com
… of plants in health care. Kerry has worked with natural product companies throughout the … Risk factors with a neonate and a toddler are not the same. The blood:breast barrier acts …
2012247 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2015-10-22. DSLD Label ID: 51645. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
Related Products
01-02-Go
Pure Nootropics
100% Caffeine
MuscleTech
100% Creatine Unflavored
Six Star Pro Nutrition
100% Creatine Unflavored
Six Star Pro Nutrition