SAMe 200 mg®
Non-Nutrient / Non-BotanicalBrand: Natural Factors
Net Contents
60 Slow Release Tablet(s)
Serving Size
1–4 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
0 68958 02708 1
Product Version
ITEM # 005401 R3
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Egg
- Fish
- Shellfish
- Tree Nuts
- Wheat
- Soy
- Gluten
Free From
- Milk
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1–4 Tablet(s) · 2 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAMe | 200 mg | — |
| S-Adenosyl-L-Methionine Tosylate Disulfate | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Usage (for adults only): Take on an empty stomach during the day. For mood balance: 1-4 tablets 2 times per day or as directed by a health professional. For joint support: 1-3 tablets 2 times per day or as directed by a health professional. Do not exceed a total of 8 tablets per day. For best results, take SAMe for a minimum of 2 weeks, at which time effects should be observed.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.
Precautions re: All Other
Individuals with bipolar disorder or depression, anxiety disorders, or taking antidepressant medication should consult their health professional prior to use.
Precautions re: Children
Keep out of the reach of children.
Precautions re: All Other
Sealed for your protection. Do not use if seal is broken.
Storage
Storage
For freshness, store in a cool, dry place. For optimum freshness, refrigerate after opening.
Formulation
Formula re: Contains
SAMe supports mood and has a positive effect on emotional well-being. It also maintains joint health. Natural Factors SAMe is released slowly.
Formulation re: Other
Manufactured to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.
Formulation re: Does NOT Contain
Contains no artificial colors, preservatives or sweeteners; no dairy, wheat, gluten, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans.
Formulation re: Other
PRODUCT OF U.S.A.
Formulation re: Other
Mood & joint support
FDA Statements
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
ISURA NON-GMO MASS SPEC Documentation Lab Tested
General Statements: All Other Content
Recyclable container and label.
Manufacturer & Distributor
Manufacturer
Natural Factors Canada
Distributor
Natural Factors
14224 167th Avenue SE, Monroe, WA, 98272
Market Reference
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NOW Foods SAMe 200 mg 60 Veg Capsules
Dr. Judy Morgan's Naturally Healthy Pets4.6(14)$39.99
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Metabolic Maintenance SAMe 200 mg 60 Capsules
Herbs Direct4.5(26)$70.00
Where to Buy Locally
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The Vitamin Shoppe
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30120 Haun Rd, Menifee, CA 92584
Wholesale Nutrition Center
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Nutrishop Moreno Valley
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12950 Day St STE 103, Moreno Valley, CA 92553
Pure Nutrition
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9496 Magnolia Ave Ste 102, Riverside, CA 92503
Pure Nutrition
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8735 Trautwein Rd suite A, Riverside, CA 92508
Healthy Body Nutrition
4.8 (48)Vitamin & supplements store
7900 Limonite Ave k, Riverside, CA 92509
Max Muscle Nutrition
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19069 Van Buren Boulevard, Riverside, CA 92508
The Vitamin Shoppe
4.4 (98)Vitamin & supplements store
2692 Canyon Springs Pkwy # A, Riverside, CA 92507
Research & Studies
Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate …
H Ullah, A Di Minno, C Esposito, HR El-Seedi… - Biomedicine & …, 2022 - Elsevier
… of a food supplement based on a combination of S-adenosyl methionine (SAMe, 200 mg/day) … In conclusion, the daily intake of the food supplement based on SAMe and probiotic strains …
202275 citationsS-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]
WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer
… On most functional health measures both groups showed a notable improvement from … -Methionine (SAMe) used in this study was enteric coated 200 mg tablets from 400 mg S-Adenosyl…
2004213 citationsHerbs and natural supplements, volume 2: An evidence-based guide
L Braun, M Cohen - 2014 - books.google.com
… herbal and nutritional supplements, and informed advice from their healthcare practitioner is … in the liver: 200 mg/kg of A. vasica was shown to be comparable to 25 mg/kg of silymarin. In …
2014569 citationsMRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial
Heart Protection Study Collaborative Group - The Lancet, 2002 - Elsevier
… , or diabetes were randomly allocated to receive antioxidant vitamin supplementation (600 mg vitamin E, 250 mg vitamin C, and 20 mg β-carotene daily) or matching placebo. Intention-…
20021,648 citationsDietary supplements and natural products as psychotherapeutic agents
A Fugh-Berman, JM Cott - Biopsychosocial Science and Medicine, 1999 - journals.lww.com
… On examination later the same day, her vital signs and results of physical examination, … healthy volunteers, a kava extract (200 mg) was compared with a high dose of oxazepam (75 mg) …
1999229 citationsBotanical medicines: the desk reference for major herbal supplements
DJ McKenna, K Jones, K Hughes, VM Tyler - 2012 - books.google.com
… of plants in health care. Kerry has worked with natural product companies throughout the … Risk factors with a neonate and a toddler are not the same. The blood:breast barrier acts …
2012247 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-01-23. DSLD Label ID: 282629. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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