No Flush Niacin 500 mg®

Other Combinations

Brand: Natural Factors

CapsuleOther CombinationsOn Market

Functions

Heart & Circulation

Product label for No Flush Niacin 500 mg — Click to view full label

Net Contents

90 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 68958 01223 0

Product Version

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

2Active Ingredients

2 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

Egg
Fish
Shellfish
Tree Nuts
Wheat
Soy
Gluten

Free From

Milk

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1–3 per day

Ingredient	Amount Per Serving	% Daily Value
Niacin(Inositol Hexaniacinate)	500 mg	3125%
Inositol(Inositol Hexaniacinate)	120 mg	—

Not Present

Other Ingredients

Microcrystalline CelluloseGelatin CapsuleMagnesium Stearate

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Usage: 1 capsule 1-3 times per day or as directed by a health professional.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Precautions re: Children

Keep out of the reach of children.

Precautions re: All Other

Sealed for your protection. Do not use if seal is broken.

Storage

For freshness, store in a cool, dry place.

Formulation

Formula re: Contains

No Flush Niacin contains inositol hexaniacinate, a form of niacin (vitamin B3) used in Europe for over 40 years. Inositol hexaniacinate is not associated with the side effects of other forms of niacin in high doses, such as flushing of the skin and upset stomach.

Formulation re: Other

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Formulation re: Does NOT Contain

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Formula re: Contains

Inositol hexaniacinate

FDA Statements

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Seals/Symbols

isura Non-GMO - Mass Spec Documentation Lab tested

General Statements: All Other Content

Product of Canada Recyclable container and label.

Seals/Symbols

Purity & Potency Guaranteed

Brand IP Statement(s) re: (c), (TM), (SM)

isura is a trademark of ISURA.

Manufacturer & Distributor

Manufacturer

Natural Factors Canada

Distributor

Natural Factors

14224 167th Avenue SE, Monroe, WA, 98272

Market Reference

$6.00 – $48.04· 40 listings

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iHerb4.6(590)
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$6.33
Natural Factors No Flush Niacin
HSU &4.6(590)
$17.21
Niacin Flush Free 500 Mg Cap, 500 MG Capsules
Amazon.com
$7.50
Spring Valley Niacin Metabolism Support Dietary Supplement Capsules, 500 mg, 240
Walmart4.5(336)
$14.84
Walgreens Flush Free Niacin
Walgreens.com
$17.99
No-flush Niacin 500 Mg
EarthTurns.com
$19.98
Source Naturals No-Flush Niacin
Walmart - Health Chest4.8(233)
$9.99

Where to Buy Locally

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GNC
4.0 (43)
Vitamin & supplements store
1625 K St NW, Washington, DC 20006
Directions (202) 822-6900
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2460 Market St NE #701, Washington, DC 20018
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206 N Washington St #100, Alexandria, VA 22314
Directions (844) 726-6965
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3.9 (32)
Vitamin & supplements store
1728 L St NW, Washington, DC 20036
Directions (202) 457-0097
The Vitamin Shoppe
4.4 (175)
Vitamin & supplements store
5524 Leesburg Pike Service Rd, Falls Church, VA 22041
Directions (703) 671-2445
GNC
4.3 (48)
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1100 S Hayes St, Arlington, VA 22202
Directions (703) 415-1322
The Vitamin Shoppe
4.4 (72)
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10 University Blvd W, Silver Spring, MD 20901
Directions (301) 593-0595
The Vitamin Shoppe
3.5 (94)
Vitamin & supplements store
3725-B Richmond Hwy, Alexandria, VA 22305
Directions (703) 535-6500

Research & Studies

Niacin and butyrate: nutraceuticals targeting dysbiosis and intestinal permeability in Parkinson's disease
TB Karunaratne, C Okereke, M Seamon, S Purohit… - Nutrients, 2020 - mdpi.com
… Niacin supplementation has been shown to shift … decreased niacin levels compared to age-matched healthy controls [52]. … and water, typically have little to no flushing effect. Moreover, …
202053 citations
Nutrition Information Briefs-Niacin
ML Meyer-Ficca, CCS Chini - Advances in Nutrition, 2026 - Elsevier
… niacin supplementation has demonstrated benefits across a range of conditions, including cancer, cardiovascular disease, skin health, mental health… the skin flushing reaction frequently …
2026
Prolonged-release nicotinic acid: a review of its use in the treatment of dyslipidaemia
PL McCormack, GM Keating - Drugs, 2005 - Springer
… without adversely affecting glycaemic control in the majority of patients. The incidence of vasodilatory flushing with PR nicotinic acid is … in 27 subjects (presumed healthy volunteers).[26] …
2005119 citations
Triglyceride lowering drugs
KR Feingold - Endotext [Internet], 2025 - ncbi.nlm.nih.gov
… No flush” niacin is also available but is generally ineffective as a lipid-modifying agent because most of these preparations do not contain active nicotinic acid… supplementation does not …
202583 citations
B vitamins in dermatology
SK Ghosh, D Bandyopadhyay, S Panja - Clinics in Dermatology, 2026 - Elsevier
… Health Organization suggests a daily oral supplementation … In general, nicotinamide-containing supplements are … profile than niacin, which is often limited by cutaneous flushing. Initially, …
20261 citations
Clinical evidence for targeting NAD therapeutically
D Radenkovic, Reason, E Verdin - Pharmaceuticals, 2020 - mdpi.com
… NAD supplementation in a range of skin, metabolic and age-related conditions. In addition, we sought medical … High doses of niacin cause headaches, skin flushing, and dizziness [58]. …
202074 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-05-22. DSLD Label ID: 220656. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.