Horse Chestnut With Grape Seed Extract®

Botanicals & Herbs

Brand: Natural Factors

CapsuleBotanicalOff Market
Click to view full label

Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 68958 04590 0

Product Version

R3

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

2Active Ingredients

2 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 2 per day

IngredientAmount Per Serving
Horse Chestnut300 mg
Escin(Triterpene Glycosides)54 mg
Grape Seed50 mg
Proanthocyanidins40 mg

Not Present

Other Ingredients

Gelatin capsuleRice powderMagnesium StearateSilica

Target Groups

Adult (18 - 50 Years)Dairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Usage: 1 capsule every 12 hours or as directed by a health professional.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Caution: Not recommended for pregnant or lactating women.

Precautions re: All Other

Sealed for your protection. Do not use if seal is broken.

Precautions re: Children

Keep out of reach children.

Precautions re: All Other

Do not take this product if you have kidney, liver or heart problems unless under the direction of a physician. If you have any adverse side effects, discontinue use and see a physician.

Storage

Storage

For freshness, store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Contains no artificial preservatives, color or sweeteners; no corn, dairy or yeast.

FDA Statements

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Other Label Statements

General Statements: All Other Content

PRODUCT OF CANADA

Seals/Symbols

(recycle) Recyclable container.

Seals/Symbols

Purity & Potency Guaranteed

General Statements: All Other Content

SUPPORT FOR HEALTHY VEINS AND CAPPILLARIES*

General Statements: All Other Content

Horse Chestnut with Grape Seed is a unique antioxidant combination that supports the circulatory system.

General Statements: All Other Content

All Natural Factors products are manufactured in accordance with the Government of Canada's Good Manufacturing Practices (GMP), among the highest standards in the world.

Seals/Symbols

STANDARDIZED POTENCY

General Statements: All Other Content

Escin (Horse Chestnut's active component) strengthens veins to prevent the fluid leakage out of blood vessels which can lead to swelling. Grape Seed is a clinically proven free radical scavenger, which prevents cellular damage in the body. Together, Horse Chestnut and Grape Seed are effective in maintaining the structural integrity of veins and capillaries that are frequently exposed to stress.*

General: Product/Version Code

R3

General Statements: All Other Content

350 mg

Manufacturer & Distributor

Manufacturer

Natural Factors, Canada

Distributor

Natural Factors

1111-80th St. SW, Ste. 100, Everett, WA, 98203, USA

Market Reference

$8.25 – $101.70· 13 listings
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  • Horse Chestnut 60 caps Natural Factors

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  • Natural Factors Sleep Relax Formula 90 Capsules

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  • Natural Factors 60 Softgels

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  • Horse Chestnut Natural Seed Powder Extract

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  • Nature's Way Horsechestnut Standardised Extract 90 Capsules

    Woocommerce - spectrumsupplements4.7(803)
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  • (2 pack) Best Naturals Horse Chestnut Extract 300 mg 180 Tablets, Size: 0.00 x 0.00 x 0.00, White

    Walmart - Best Naturals4.8(40)
    $26.08

Where to Buy Locally

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Research & Studies

  • The Role of Botanicals in Cardiovascular Health

    TL Dog - Nutritional and Integrative Strategies in Cardiovascular …, 2022 - taylorfrancis.com

    … Grape seed oil is growing in popularity as a heart-healthy cooking … The primary active constituent found in horse chestnut seed extract is aescin – most horse chestnut seed extracts are …

    20222 citations
  • Chestnut and Grapevine By-Products: Bioactivity, Biotransformation, and Nutraceutical Applications

    T Pinto, B Gonçalves, A Aires, F Cosme, A Vilela - Applied Sciences, 2026 - mdpi.com

    … skins, while HPLC coupled with fluorescence or mass spectrometry has been used to detect minor polyphenols in grape seed extracts [108]. HPLC is not only useful for direct …

    2026
  • Cosmeceuticals containing herbs: fact, fiction, and future

    C Thornfeldt - Dermatologic Surgery, 2005 - Wiley Online Library

    … horse chestnut reduced the symptoms of CVI in one trial and hemorrhoids in another.Photoaging clinical studies are lacking. The health risks of horse chestnut … than grape seed extract, …

    2005283 citations
  • Effect of horse chestnut and inulin as single supplements or in combination on chemically induced colon cancer in rats.

    V Szabadosova, E Hijova, L Strojny, R Salaj, A Bomba… - 2013 - agriculturejournals.cz

    … Horse chestnut (Aesculus hippocastanum) extract is widely used in the pharmaceutical and cosmetic industries. Aescin is the medical constituent of Aesculus hippocastanum seeds, a …

    20135 citations
  • Feeding grape seed extract to horses: effects on health, intake and digestion

    JA Davies, GL Krebs, A Barnes, I Pant, PJ McGrath - Animal, 2009 - cambridge.org

    … race horses was undertaken to establish whether inclusion of grape seed extract (GSE) in the diet of horses undergoing mild exercise had any effects on their general health, intake and …

    200920 citations
  • Mineral composition analysis of red horse-chestnut (Aesculus× Carnea) seeds and hydroalcoholic crude extract using ICP OES

    V D'Eusanio, A Marchetti, M Rivi, L Morelli, P Scarponi… - Molecules, 2025 - iris.unimore.it

    … Abstract: This study presents findings on the metal and metalloid composition of red horsechestnut (Aesculus × carnea, AXC) seeds, determined by the ICP OES technique. Samples …

    20257 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-06-25. DSLD Label ID: 9535. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.