Net Contents
60 Enteric Coated Caplet(s)
Serving Size
1 Enteric Coated Caplet(s)
Servings Per Container
Not specified
Supplement Form
Other (e.g. tea bag)
Bar Code (UPC/SKU)
0 68958 02814 9
Product Version
R1
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
2 distinct active ingredients are disclosed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
1 ingredients report an established %DV per serving.
Label states: Vegan, Vegetarian, Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Egg
- Fish
- Shellfish
- Wheat
- Soy
- Gluten
Free From
- Milk
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Enteric Coated Caplet(s) · 2–3 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Calcium(Dicalcium Phosphate) | 100 mg | 10% |
| 5-HTP(Griffonia simplicifolia) | 130 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Usage: 1 caplet 2-3 times per day with meals or as directed by a health professional. To minimize the risk of gastrointestinal side effects, slowly increase dose over a period of 2 weeks.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate surgery.
Precautions re: Children
Keep out of the reach of children.
Precautions re: All Other
Sealed for your protection. Do not use if seal is broken.
Storage
Storage
For freshness, store in a cool, dry place.
Formulation
Formulation re: Does NOT Contain
Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, or GMOs.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans.
Formula re: Contains
Free form amino acid
FDA Statements
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
isura Non-GMO - Mass spec Documentation - Lab tested
General Statements: All Other Content
5-HTP is an intermediate metabolite between l-tryptophan and serotonin. Supplementing with 5-HTP provides natural support for sleep and emotional well-being. Enteric coated caplets minimize gastric discomfort and optimize absorption. Natural Factors amino acids are the highest quality pharmaceutical grade products available.
General Statements: All Other Content
Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.
General Statements: All Other Content
Product of Canada. Recyclable container and label.
Seals/Symbols
Purity & potency guaranteed
General Statements: All Other Content
100 mg
General Statements: All Other Content
Emotional well-being
General: Product/Version Code
R1
Manufacturer & Distributor
Manufacturer
Natural Factors Canada
Distributor
Natural Factors
14224 167th Avenue SE, Monroe, WA, 98272
Market Reference
Natural Factors Stress-Relax 5-HTP
Walmart - Pattern4.8(5)$13.97
Natural Factors 5-HTP
Village Vitamin Store4.7(164)$12.11
Natural Factors Stress- Relax Tranquil Sleep Enteric Coated Softgels
iHerb4.6(217)$13.97
Natural Factors Stress- Relax Extra Strength Tranquil Sleep Chewable Tablets
Walmart - Pattern4.4(28)$34.97
Natural Factors Melatonin Stress-Relax
iHerb4.8(2700)$8.37Lowest
5-Htp
ZANVA$29.95
5-HTP
Soytopia$32.99
Double Wood Supplements 5-HTP Liquid Drops
Target4.6(19)$19.95
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Big Dan's Nutrition, Lewiston, Clarkston
4.7 (94)Vitamin & supplements store
107 Thain Rd, Lewiston, ID 83501
Vig's Health Food Store
4.8 (78)Vitamin & supplements store
922 16th Ave, Lewiston, ID 83501
GNC
4.2 (37)Vitamin & supplements store
1804 19th Ave Ste C, Lewiston, ID 83501
Patriot Supplements Health and Wellness
4.9 (58)Vitamin & supplements store
2834 N Ramsey Rd Unit 101, Coeur d'Alene, ID 83815
C R Supplements, LLC
5.0 (9)Vitamin & supplements store
102 Main St #445, Kooskia, ID 83539
GNC
4.4 (11)Vitamin & supplements store
1656 S Grand Ave, Pullman, WA 99163
Post Falls Sports Nutrition
5.0 (42)Vitamin & supplements store
724 ID-41 Ste B, Post Falls, ID 83854
The Vitamin Shoppe
4.4 (164)Vitamin & supplements store
403 W Neider Ave, Coeur d'Alene, ID 83815
Research & Studies
The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine
N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com
… TPH, a rate-limiting enzyme for 5-HT production, plays a key role in the conversion of Trp to 5-hydroxytryptophan (5-HTP) [1,35]. 5-HT is rapidly converted to 5-HT by aromatic L-amino …
2021261 citationsThe Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com
… body composition management and mental health regulation [21,23… healthy and had not previously taken 5-HTP supplementation, 100 mg was selected to balance the potential benefits …
20254 citationsEffects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
F Javelle, A Lampit, W Bloch, P Häussermann… - … reviews, 2020 - academic.oup.com
… As will be discussed below, 5-HTP may have some benefits compared to TRP. This meta-… Reviews and Meta-Analysis) guidelines, aimed to evaluate the findings concerning 5-HTP as a …
202062 citationsA Ratio-Defined 5-HTP/L-Theanine/GABA Oral Composition for Sleep Initiation and Sleep Maintenance
J Hoffmann, J Yassine, GL Semenza - Journal of Technology …, 2026 - sci-open.net
… Across the patent-reported medium-dose groups, escalating 5-HTP from 5 to 30 mg… 5-HTP-alone comparator groups. When placed in the context of published human evidence on 5-HTP…
2026Targeting Serotonin through Nutrition: Systematic Review of Tryptophan and 5-HTP for Mood and Cognitive Dysfunction
R Ajax - researchgate.net
… that tryptophan and 5-HTP supplementation offer measurable benefits for mood regulation and, to … While both compounds modulate serotonin synthesis effectively, 5HTP shows greater …
The Role of Kynurenine and 5-Hydroxytryptophan in Modulating Microbiota and Their Implications in Exudative Age-Related Macular Degeneration
A Vilkeviciute-Petraite, A Bruzaite, D Cebatoriene… - Diagnostics, 2026 - mdpi.com
2026
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-07-25. DSLD Label ID: 75819. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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