5-HTP

Suggested Use

Suggested Usage: 1 caplet 2-3 times per day with meals or as directed by a health professional. To minimize the risk of gastrointestinal side effects; slowly increase dose over a period of 2 weeks.

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  Natural Factors Stress-Relax 5-HTP

  Walmart - Pattern4.8(5)

  $13.97
• 

  Natural Factors 5-HTP

  Village Vitamin Store4.7(164)

  $12.11
• 

  Natural Factors Stress- Relax Tranquil Sleep Enteric Coated Softgels

  iHerb4.6(217)

  $13.97
• 

  Natural Factors Stress- Relax Extra Strength Tranquil Sleep Chewable Tablets

  Walmart - Pattern4.4(28)

  $34.97
• 

  Natural Factors Melatonin Stress-Relax

  iHerb4.8(2700)

  $8.37Lowest
• 

  5-Htp

  ZANVA

  $29.95
• 

  5-HTP

  Soytopia

  $32.99
• 

  Double Wood Supplements 5-HTP Liquid Drops

  Target4.6(19)

  $19.95

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• Big Dan's Nutrition, Lewiston, Clarkston

  4.7 (94)

  Vitamin & supplements store

  107 Thain Rd, Lewiston, ID 83501

  Directions(208) 816-8396

• Vig's Health Food Store

  4.8 (78)

  Vitamin & supplements store

  922 16th Ave, Lewiston, ID 83501

  Directions(208) 746-7044

• GNC

  4.2 (37)

  Vitamin & supplements store

  1804 19th Ave Ste C, Lewiston, ID 83501

  Directions(208) 743-4462

• Patriot Supplements Health and Wellness

  4.9 (58)

  Vitamin & supplements store

  2834 N Ramsey Rd Unit 101, Coeur d'Alene, ID 83815

  Directions(208) 667-1667

• C R Supplements, LLC

  5.0 (9)

  Vitamin & supplements store

  102 Main St #445, Kooskia, ID 83539

  Directions(208) 926-4639

• GNC

  4.4 (11)

  Vitamin & supplements store

  1656 S Grand Ave, Pullman, WA 99163

  Directions(509) 332-0301

• Post Falls Sports Nutrition

  5.0 (42)

  Vitamin & supplements store

  724 ID-41 Ste B, Post Falls, ID 83854

  Directions(208) 981-0649

• The Vitamin Shoppe

  4.4 (164)

  Vitamin & supplements store

  403 W Neider Ave, Coeur d'Alene, ID 83815

  Directions(208) 665-1500

• The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine

  N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com

  … TPH, a rate-limiting enzyme for 5-HT production, plays a key role in the conversion of Trp to 5-hydroxytryptophan (5-HTP) [1,35]. 5-HT is rapidly converted to 5-HT by aromatic L-amino …

  2021261 citations

• The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial

  S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com

  … body composition management and mental health regulation [21,23… healthy and had not previously taken 5-HTP supplementation, 100 mg was selected to balance the potential benefits …

  20254 citations

• Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis

  F Javelle, A Lampit, W Bloch, P Häussermann… - … reviews, 2020 - academic.oup.com

  … As will be discussed below, 5-HTP may have some benefits compared to TRP. This meta-… Reviews and Meta-Analysis) guidelines, aimed to evaluate the findings concerning 5-HTP as a …

  202062 citations

• A Ratio-Defined 5-HTP/L-Theanine/GABA Oral Composition for Sleep Initiation and Sleep Maintenance

  J Hoffmann, J Yassine, GL Semenza - Journal of Technology …, 2026 - sci-open.net

  … Across the patent-reported medium-dose groups, escalating 5-HTP from 5 to 30 mg… 5-HTP-alone comparator groups. When placed in the context of published human evidence on 5-HTP…

  2026

• Targeting Serotonin through Nutrition: Systematic Review of Tryptophan and 5-HTP for Mood and Cognitive Dysfunction

  R Ajax - researchgate.net

  … that tryptophan and 5-HTP supplementation offer measurable benefits for mood regulation and, to … While both compounds modulate serotonin synthesis effectively, 5HTP shows greater …

• The Role of Kynurenine and 5-Hydroxytryptophan in Modulating Microbiota and Their Implications in Exudative Age-Related Macular Degeneration

  A Vilkeviciute-Petraite, A Bruzaite, D Cebatoriene… - Diagnostics, 2026 - mdpi.com

  2026

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-07-25. DSLD Label ID: 75819. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.