Brand: Natrol

Tablet or PillNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

20 Enteric Coated Tablet(s)

Serving Size

2 Tablet(s)

Servings Per Container

10

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 47469 16141 5

Product Version

ITEM: 16141 F: 3000008 B: 2007417-13015

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Milk

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Tablet(s) · 1 per day

IngredientAmount Per Serving
S-Adenosyl-Methionine(S-Adenosyl-Methionine Disulfate Tosylate)400 mg

Not Present

Other Ingredients

CelluloseCellulose GumMethacrylate PolymerMagnesium StearateStearic AcidSilicaCitric AcidAscorbic AcidTriethyl CitrateColored with Riboflavin and Titanium Dioxide

Target Groups

VegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: Take 2 tablets, one time daily, with a meal.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Consult your healthcare professional prior to use if you have or suspect a medical condition, or are taking prescription drugs or any prescription antidepressant. Do not use this product if you have bipolar disorder (manic depression) or are pregnant or lactating.

Precautions re: Children

Keep out of reach of children.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

No milk, egg, fish, crustacean shellfish, tree nuts, wheat, peanuts, soybeans, yeast, corn, glutens, artificial flavors, added sugar, starch or preservatives

Formula re: Contains

SAMe 400 mg per serving

Formulation re: Vegetarian/Vegan

100% vegetarian

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

SAMe (S-Adenosyl-Methionine) is an amino acid that is produced by the body for positive mood. Diet, aging and other factors may lower SAMe levels.

Brand IP Statement(s) re: (c), (TM), (SM)

Fortunately Natrol SAMe helps support beneficial levels of SAMe in the body.

General Statements: All Other Content

SAMe is also beneficial for joint comfort and healthy liver function.

General Statements: All Other Content

Made in USA

General: Product/Version Code

ITEM: 16141 F: 3000008 B: 2007417-13015

General Statements: All Other Content

Helps support mood SAMe helps support healthy liver function Promote joint health

Manufacturer & Distributor

Distributor

NATROL, INC.

Chatsworth, CA, 91311

Market Reference

$6.99 – $74.99· 38 listings
  • Nature Made SAM-e Complete 400 mgNature Made SAM-e Complete 400 mg

    Walmart
    $52.97
  • Walgreens Sam-e 400 mg Coated CapletsWalgreens Sam-e 400 mg Coated Caplets

    Walgreens.comFree deliveryFree delivery
    $49.99
  • Nutralife The Original SAMe 400 mg Enteric Coated TabletsNutralife The Original SAMe 400 mg Enteric Coated Tablets

    TargetFree delivery on $35+Free delivery on $35+
    $22.99
  • Natrol Ultra Sleep 3-in-1 Fast Dissolve TabletsNatrol Ultra Sleep 3-in-1 Fast Dissolve Tablets

    WalmartNext-day delivery $7Next-day delivery $7
    $8.09
  • Natrol Melatonin Free Sleep & Restore 60 CapsulesNatrol Melatonin Free Sleep & Restore 60 Capsules

    TargetFree delivery on $35+Free delivery on $35+
    $22.99
  • Spring Valley SAMeSpring Valley SAMe

    WalmartNext-day delivery $7Next-day delivery $7
    $24.96
  • Denestra SAMe 400mg 60 TabletsDenestra SAMe 400mg 60 Tablets

    Chewy.comFree delivery by SatFree delivery by Sat
    $49.49
  • BESTVITE Same 400mg 30 TabletsBESTVITE Same 400mg 30 Tablets

    Walmart - BESTVITE INCFree deliveryFree delivery
    $19.99

Where to Buy Locally

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Research & Studies

  • Efficacy of the Dietary Supplement S-Adenosyl-L-Methionine

    CW Fetrow, JR Avila - Annals of Pharmacotherapy, 2001 - journals.sagepub.com

    … to receive oral ibuprofen 400 mg three times daily or oral SAMe 400 mg three times daily for … sold as a dietary supplement in the US under the Dietary Supplement Health Education Act. …

    200163 citations
  • Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity

    RP Brown, PL GERBARG - Journal of Psychiatric Practice, 2001 - ovid.com

    … supplements, found that only 2 out of 8 brands contained adequate hyperforin: Natures Way Standardized Extract and Natrol … Health food companies in the United States sell SAM-e in …

    200159 citations
  • Phytochemicals as nutraceuticals: a review

    JS Dhumal, AK Thikekar, AB Kumbhar… - J Neonatal …, 2025 - researchgate.net

    … effects in our health and possess medicinal activities … medical or health benefits, including the prevention and treatment of disease. Such products may range from dietary supplements …

    20251 citations
  • The Effects of Physical Activity Programs with Nutritional Supplementation in Children Until 12 Years Old Recruited from Schools: A Systematic Review of …

    M Rico-González, CD Gómez-Carmona… - Nutrients, 2025 - pmc.ncbi.nlm.nih.gov

    … health, 2–3% higher increases in bone mineral content at loaded sites were reported with exercise combined with calcium supplementation. … supplementation yield synergistic health …

    20256 citations
  • Herb-drug interactions and mechanistic and clinical considerations

    XW Chen, KB Sneed, SY Pan, C Cao… - Current drug …, 2012 - ingentaconnect.com

    … caplets (Natrol, each caplet contains 3.6 mg garlic powdered … through simultaneous effects on the same drug targets [14, 148]… and dietary supplement disclosure to health care providers …

    2012224 citations
  • Weight loss nutritional supplements

    JM Eckerson - Nutritional Supplements in Sports and Exercise, 2015 - Springer

    … Because of the medical implications and health-care costs … nutritional weight loss supplements hoping for a quick fix, and … in the same laboratory, and supplementation occurred in …

    20157 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-09-21. DSLD Label ID: 77813. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.