Melatonin TR Time Release 5 mg

Other Combinations

Brand: Natrol

Tablet or PillOff Market
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Net Contents

100 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

0 47469 04837 2

Product Version

Not specified

Suggested Use

Directions: Take 1 tablet 20 minutes before bedtime.

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Research & Studies

  • Melatonin treatment of sleep–wake cycle disorders in children and adolescents

    JE Jan, RD Freeman, DK Fast - Developmental medicine and child …, 1999 - cambridge.org

    … a nutritional supplement, has been widely available in health-… Slow- or time-release MLT tablets can be effective for 8 to 9 … 1 to 3 mg in infants and toddlers and 2.5 to 5 mg for older …

    1999170 citations
  • Chronic administration of melatonin: physiological and clinical considerations

    D Givler, A Givler, PM Luther, DM Wenger… - Neurology …, 2023 - mdpi.com

    … problems, and numerous medical illnesses, including Alzheimer… Oral melatonin supplementation has been advocated for … or more melatonin prescriptions (2 mg, extended …

    202371 citations
  • Melatonin and the nervous system: nanomedicine perspectives

    F Luo, Y Deng, B Angelov, A Angelova - Biomaterials Science, 2025 - pubs.rsc.org

    … common and serious public health problems, particularly … MT supplementation (2 mg day −1 ) improved subjective sleep … release: an early burst release phase and a slow-release phase …

    202513 citations
  • Melatonin and depression: a translational perspective from animal models to clinical studies

    AC Tonon, LK Pilz, RP Markus, MP Hidalgo… - Frontiers in …, 2021 - frontiersin.org

    … Of note, other medical conditions that can cause the same … 6 mg] and the third compared the use of 3 mg slow-release … scores after supplementation with 5 mg melatonin at bedtime. Two …

    202198 citations
  • Melatonin in children with autism spectrum disorders: endogenous and pharmacokinetic profiles in relation to sleep

    SE Goldman, KW Adkins, MW Calcutt… - Journal of autism and …, 2014 - Springer

    … We assessed endogenous and supplemental melatonin … taking supplemental melatonin (liquid, immediate release, Natrol … for exogenous melatonin in plasmafrom young healthy human …

    2014183 citations
  • Impact of exogenous melatonin on sleep and daytime functioning in healthy, typically developing adolescents

    …, KM Decker, KC Byars, TR Van Dyk - Current Sleep Medicine …, 2022 - Springer

    … , controlled-release melatonin (5 mg total: 1 mg fast, 4 mg sustained-release) administered 20… ; and, if purchased as an unregulated dietary supplement, that melatonin brands with USP …

    20224 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2011-10-26. DSLD Label ID: 1276. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.