Caffeine

Suggested Use

DirectionsHealthy adults only: As a dietary supplement take 1 tablet per day with a glass of water. To assess individual tolerance; take 1/2 tablet with a glass of water by breaking a tablet in half. Drink 8 to 10 glasses of water per day.

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• GNC

  4.1 (37)

  Vitamin & supplements store

  699 Lewelling Blvd Ste 176, San Leandro, CA 94579

  Directions(510) 357-5477

• Health Unlimited

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  182 Pelton Center Way, San Leandro, CA 94577

  Directions(510) 483-3630

• Stabilized Nutraceuticals

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  22475 Foothill Blvd, Hayward, CA 94541

  Directions(510) 329-1646

• Prime Time Nutrition

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  Health food store

  22301 Mission Blvd, Hayward, CA 94541

  Directions(510) 889-7675

• Nature's Sunshine

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  Vitamin & supplements store

  21709 Redwood Rd, Castro Valley, CA 94546

  Directions(510) 582-8482

• GNC

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  Vitamin & supplements store

  1291 Washington Street, San Leandro, CA 94577

  Directions(510) 614-9237

• HiBody LifeStyle By Nancy

  5.0 (8)

  Vitamin & supplements store

  25684 Franklin Ave, Hayward, CA 94544

  Directions(510) 999-1207

• Health Unlimited of America Inc

  4.6 (82)

  Vitamin & supplements store

  3446 Village Dr, Castro Valley, CA 94546

  Directions(510) 581-0220

• Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans

  H Li, M Roxo, X Cheng, S Zhang, H Cheng, M Wink - Food chemistry: X, 2019 - Elsevier

  … caffeine and its related methylxanthines is still not clear. In this study, we demonstrated that caffeine … Lifespan studies with the wild type, DAF-16 and SKN-1 mutant strains indicated that …

  201958 citations

• Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans

  GL Sutphin, E Bishop, ME Yanos, RM Moller… - Longevity & …, 2012 - Springer

  … on life span for strains with loss of function mutations in (1) sir-… mutated for either sir-2.1 or hif-1[46, 48, 51], we predicted that … prior evidence that caffeine can improve healthy aging in C. …

  201282 citations

• Long-term caffeine intake exerts protective effects on intestinal aging by regulating vitellogenesis and mitochondrial function in an aged Caenorhabditis …

  H Min, E Youn, YH Shim - Nutrients, 2021 - mdpi.com

  … atrophy became more severe in the mev-1 mutant that is hypersensitive to oxidative stress [30]… that links intestinal aging, mitochondrial function, and health in the context of diet-induced …

  202125 citations

• Methionine Supplementation Alleviates the Germ Cell Apoptosis Increased by Maternal Caffeine Intake in a C. elegans Model

  H Min, J Kim, M Lee, S Kang, YH Shim - Nutrients, 2024 - mdpi.com

  … -1 mutant background, an engulfment defective mutant to check whether caffeine intake affects … that methionine supplementation has a beneficial effect on germ cell health and offspring …

  20243 citations

• Effects of caffeine on the genetic material

  BA Kihlman - Mutation Research/Fundamental and Molecular …, 1974 - Elsevier

  … I am thinking about the production of gene or point mutations by caffeine. … ,,datum with caffeine produced a strong increase Jn the frequency of physiological mutants, ie, mutants which …

  1974131 citations

• Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells

  TK Leao, DL Ribeiro, ART Machado, TR Costa… - Mutation Research …, 2021 - Elsevier

  The abusive consumption of thermogenic supplements occurs worldwide and deserves special attention due to their use to stimulate weight loss and prevent obesity. Thermogenic …

  202120 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-08-22. DSLD Label ID: 333479. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.