L-5-MTHF®

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Serving Size: 1 Capsule(s) · 1 per day

Not Present

• 

  Moss Nutrition MTHF Folate Brain | Hasan Mirza MD

  Hasan Mirza, MD

  $36.00
• 

  Probase Nutrition L-Methylfolate 5-MTHF

  Target4.6(17)

  $21.99
• 

  Thorne Research 5-MTHF 5mg 60 Capsules

  Pure Prescriptions4.8(506)

  $68.00
• 

  Fresh Nutrition L Methyl Folate 7.5mg DNA Verified for Maximum Potency

  Walmart - Fresh Nutrition Inc5.0(27)

  $22.99
• 

  5-MTHF 1 mg 60 capsules

  Life Extension5.0(4)

  $24.00
• 

  Vitamatic Methylfolate Gummies 1000 mcg Active 5-MTHF Form Natural Strawberry Flavor Vegan

  Vitamatic5.0(1)

  $9.99Lowest
• 

  5 Methylfolate 5-mthf L-Methylfolate 5 mg

  methyl-life.com4.7(43)

  $44.00
• 

  Biotics Research Plus Forte 60 Tablets

  Covenant Health Products

  $49.90

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• Buffalo Nutrition

  4.9 (185)

  Vitamin & Supplements Shop

  132 Cricklewood Broadway, London NW2 3EE

  Directions020 8450 4905

• Nayble Health & Sports

  5.0 (139)

  Vitamin & Supplements Shop

  18 Chamberlayne Rd, London NW10 3JD

  Directions020 7625 5111

• HARA Health Store

  4.7 (50)

  Vitamin & Supplements Shop

  231 Finchley Rd, South Hampstead, London NW3 6LS

  Directions020 7794 5486

• Planetis Natural Health & Nutrition

  5.0 (38)

  Vitamin & Supplements Shop

  32 Clifton Rd, London W9 1ST

  Directions020 7289 4551

• Fitandfat

  5.0 (321)

  Vitamin & Supplements Shop

  Inside the post office, 187 Uxbridge Rd, London W13 9AJ

  Directions020 8050 1277

• ITL Health

  5.0 (37)

  Vitamin & Supplements Shop

  50 Broadway, London SW1H 0BL

  Directions0118 321 7628

• Protiv Nutrition

  5.0 (1)

  Vitamin & Supplements Shop

  3rd Floor, 207 Regent St., London W1B 3HH

  Directions07442 915758

• RightNutri

  4.9 (78)

  Vitamin & Supplements Shop

  26 Queenstown Rd, London SW8 3RX

  Directions0800 098 8888

• Comparative Analysis of Treatment With Folate Forms in Clinical Practice

  O Skavinska, Z Rossokha, V Stefanyshyn… - Nutrition …, 2025 - academic.oup.com

  … The use of L-5-MTHF instead of sFA may further reduce this concern, because the former does not contribute to UMFA accumulation and does not appear to mask hematologic signs of …

  20251 citations

• Conversion of calcium-l-methylfolate and (6S)-5-methyltetrahydrofolic acid glucosamine salt into dietary folate equivalents

  D Turck, T Bohn, J Castenmiller, S De Henauw… - EFSA …, 2022 - iris.unimore.it

  … A free form of L-5-MTHF acid (500 μg) was consumed as a supplement on an empty stomach. The bioavailability of 5-MTHF was estimated in urine samples by reference to the …

  202223 citations

• Supplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review

  ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com

  … and pyrimidines or can be converted into L-5-MTHF in a reaction catalysed by the methylenetetrahydrofolate reductase (MTHFR) [38]. The resulting L-5-MTHF is the predominant form …

  202426 citations

• Select Essential (Water and Fat)-soluble Vitamins--Epigenetic and Synergistic Co-dependent Roles.

  J Gantzer - Nutritional Perspectives: Journal of the Council …, 2019 - search.ebscohost.com

  … -TetraHydroFolate (L-5MTHF), a cofactor in the Methionine Cycle for Homocysteine regulation along with B12. However, due to its structural similarity to BH4, L-5-MTHF can also bind to …

  2019

• Vitamins, nutraceuticals, food additives, enzymes, anesthetic aids, and cosmetics

  ANM Alamgir - Therapeutic Use of Medicinal Plants and their Extracts …, 2018 - Springer

  … nutrients such as dietary minerals, essential fatty acids, or essential amino acids, nor does it encompass the large number of other nutrients that promote health … nutrition provide health …

  201851 citations

• An HPLC-MS-Based Method for Determination of the D- and L- 5-Methyltetrahydrofolate Isomer Ratio in Dietary Supplements

  X Wang, D Pandey, S Vavilala, L Oh… - Journal of AOAC …, 2026 - academic.oup.com

  … The DS screened in this study indicate that the adulteration of L-5-MTHF with D, L-5MTHF is not common for DS in US markets, either in prenatal MVMs sold through pharmacies or from …

  20261 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-03-25. DSLD Label ID: 247146. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.