L-5-MTHF®

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Serving Size: 1 Capsule(s) · 1 per day

Not Present

• 

  Moss Nutrition L-5-MTHF - 120 caps

  Rooted Nutrition

  $36.00
• 

  Moss Nutrition L-5-MTHF - 500 mg

  Hasan Mirza, MD

  $36.00
• 

  Moss Nutrition B12 Methylfolate Select - 60 ct

  Rooted Nutrition

  $28.00
• 

  Moss Nutrition 5-HTP Select - 90 caps

  Rooted Nutrition

  $12.00
• 

  Moss Nutrition 5-HTP Select - 90 VC

  Hasan Mirza, MD

  $20.00
• 

  L-Methylfolate Plus Methyl-B12

  Triquetra Health4.2(267)

  $15.99
• 

  MaryRuth's Sea Moss + Citrus Berry Liposomal

  Whole Foods Market4.8(61)

  $24.99
• 

  Moss Nutrition Elemental Select - 1.04 kg

  Hasan Mirza, MD

  $130.00

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• Elan Vital Natural Health Center

  4.6 (11)

  Vitamin & supplements store

  Budapest, Síp u. 6, 1075 Hungary

  Directions+36 1 788 2577

• Mani Vitamīni

  4.8 (11)

  Vitamin & supplements store

  Lāčplēša iela 14, Centra rajons, Rīga, LV-1011, Latvia

  Directions+371 29 482 225

• Emporio nel Bosco

  4.9 (177)

  Vitamin & supplements store

  Via Enrico Fermi, 2, 25133 Brescia BS, Italy

  Directions+39 352 088 5612

• Equisalud

  4.5 (59)

  Vitamin & supplements store

  C. Mutiloa, 2, 31620 Huarte, Navarra, Spain

  Directions+34 948 13 13 01

• Geo Paleo Diet Shop

  4.8 (238)

  Grocery store

  Via Baldo degli Ubaldi, 232, 00167 Roma RM, Italy

  Directions+39 06 6935 7264

• Ringnaturshop

  4.7 (137)

  Vitamin & supplements store

  Kreuzgasse 4, 7423 Pinkafeld, Austria

  Directions+43 59 957

• Revita

  4.5 (29)

  Store

  Bulevar Zorana Đinđića 125, Beograd, Serbia

  Directions+381 800 151516

• Bioherbs

  4.1 (15)

  Vitamin & supplements store

  Route Lido Nabeul, Dar Chaabane Al Fehri 8011, Tunisia

  Directions+216 24 289 289

• Conversion of calcium‐l‐methylfolate and (6S)‐5‐methyltetrahydrofolic acid glucosamine salt into dietary folate equivalents

  EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2022 - Wiley Online Library

  … A free form of L-5-MTHF acid (500 μg) was consumed as a supplement on an empty stomach. The bioavailability of 5-MTHF was estimated in urine samples by reference to the …

  202221 citations

• Comparative Analysis of Treatment With Folate Forms in Clinical Practice

  O Skavinska, Z Rossokha, V Stefanyshyn… - Nutrition …, 2025 - academic.oup.com

  … The use of L-5-MTHF instead of sFA may further reduce this concern, because the former does not contribute to UMFA accumulation and does not appear to mask hematologic signs of …

  20251 citations

• Supplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review

  ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com

  … and pyrimidines or can be converted into L-5-MTHF in a reaction catalysed by the methylenetetrahydrofolate reductase (MTHFR) [38]. The resulting L-5-MTHF is the predominant form …

  202425 citations

• Select Essential (Water and Fat)-soluble Vitamins--Epigenetic and Synergistic Co-dependent Roles.

  J Gantzer - Nutritional Perspectives: Journal of the Council …, 2019 - search.ebscohost.com

  … -TetraHydroFolate (L-5MTHF), a cofactor in the Methionine Cycle for Homocysteine regulation along with B12. However, due to its structural similarity to BH4, L-5-MTHF can also bind to …

  2019

• An HPLC-MS-Based Method for Determination of the D- and L- 5-Methyltetrahydrofolate Isomer Ratio in Dietary Supplements

  X Wang, D Pandey, S Vavilala, L Oh… - Journal of AOAC …, 2026 - academic.oup.com

  … The DS screened in this study indicate that the adulteration of L-5-MTHF with D, L-5MTHF is not common for DS in US markets, either in prenatal MVMs sold through pharmacies or from …

  2026

• Vitamins, nutraceuticals, food additives, enzymes, anesthetic aids, and cosmetics

  ANM Alamgir - Therapeutic Use of Medicinal Plants and their Extracts …, 2018 - Springer

  … nutrients such as dietary minerals, essential fatty acids, or essential amino acids, nor does it encompass the large number of other nutrients that promote health … nutrition provide health …

  201850 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-03-25. DSLD Label ID: 247146. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.