L-5-MTHFnone

Vitamins

Brand: Moss Nutrition

CapsuleVitaminOff Market
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Net Contents

120 Vegetarian Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

120

Supplement Form

Capsule

Bar Code (UPC/SKU)

M093

Product Version

V.0817.5

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Capsule(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Folate(Glucosamine Salt, Quatrefolic (6S)-5-Methyltetrahydrofolic Acid)1000 mcg250%

Not Present

Other Ingredients

Microcrystalline CelluloseHypromelloseVegetable StearateSilicon Dioxide

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested use: 1 capsule per day or as directed by your healthcare professional.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: If taking medication, pregnant or nursing, consult a physician before using.

Precautions re: Children

Keep out of reach of children.

Storage

Storage

Store sealed in a cool, dry place.

Formulation

Formula re: Contains

Quatrefolic

Formulation re: Does NOT Contain

Does not contain gluten.

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Brand IP Statement(s) re: (c), (TM), (SM)

Quatrefolic is a registered trademark of Gnosis S.p.A.

Brand IP Statement(s) re: (c), (TM), (SM)

M Professional Supplements Est. 1991

General Statements: All Other Content

Natural S-Isomer

General Statements: All Other Content

Support for healthy methylation

General: Product/Version Code

V.0817.5

Manufacturer & Distributor

Distributor

Moss Nutrition Products, Inc.

380 Russell Street, Hadley, MA, 01035

800-851-5444

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Research & Studies

  • Conversion of calcium‐l‐methylfolate and (6S)‐5‐methyltetrahydrofolic acid glucosamine salt into dietary folate equivalents

    EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2022 - Wiley Online Library

    … A free form of L-5-MTHF acid (500 μg) was consumed as a supplement on an empty stomach. The bioavailability of 5-MTHF was estimated in urine samples by reference to the …

    202223 citations
  • Comparative Analysis of Treatment With Folate Forms in Clinical Practice

    O Skavinska, Z Rossokha, V Stefanyshyn… - Nutrition …, 2025 - academic.oup.com

    … The use of L-5-MTHF instead of sFA may further reduce this concern, because the former does not contribute to UMFA accumulation and does not appear to mask hematologic signs of …

    20251 citations
  • Supplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review

    ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com

    … and pyrimidines or can be converted into L-5-MTHF in a reaction catalysed by the methylenetetrahydrofolate reductase (MTHFR) [38]. The resulting L-5-MTHF is the predominant form …

    202426 citations
  • Select Essential (Water and Fat)-soluble Vitamins--Epigenetic and Synergistic Co-dependent Roles.

    J Gantzer - Nutritional Perspectives: Journal of the Council …, 2019 - search.ebscohost.com

    … -TetraHydroFolate (L-5MTHF), a cofactor in the Methionine Cycle for Homocysteine regulation along with B12. However, due to its structural similarity to BH4, L-5-MTHF can also bind to …

    2019
  • Vitamins, nutraceuticals, food additives, enzymes, anesthetic aids, and cosmetics

    ANM Alamgir - Therapeutic Use of Medicinal Plants and their Extracts …, 2018 - Springer

    … nutrients such as dietary minerals, essential fatty acids, or essential amino acids, nor does it encompass the large number of other nutrients that promote health … nutrition provide health …

    201851 citations
  • An HPLC-MS-Based Method for Determination of the D- and L- 5-Methyltetrahydrofolate Isomer Ratio in Dietary Supplements

    X Wang, D Pandey, S Vavilala, L Oh… - Journal of AOAC …, 2026 - academic.oup.com

    … The DS screened in this study indicate that the adulteration of L-5-MTHF with D, L-5MTHF is not common for DS in US markets, either in prenatal MVMs sold through pharmacies or from …

    20261 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-04-25. DSLD Label ID: 188693. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.