Brand: Metagenics

Tablet or PillBotanicalOff Market
Click to view full label

Net Contents

56 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

56

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 55571 94719 2

Product Version

ESDISSAM 1544522C2

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3Dietary Attributes

Label states: Vegetarian, Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1 per day

Not Present

Other Ingredients

Microcrystalline CelluloseStearic AcidCroscarmellose SodiumSilicaEnteric Coating

Target Groups

VegetarianWomen (not pregnant or lactating)Adult Female (18 - 50 Years)MenopauseSeniors/Mature (>50 Years) - Women ONLYGluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: Take one tablet with food and a glass of water once daily at the same time of day or as directed by your healthcare practitioner.

Suggested/Recommended/Usage/Directions

Simple dosing Well-tolerated, once-daily tablet

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Caution: Do not use if pregnant or nursing. If taking medication, consult your healthcare practitioner before use.

Precautions re: All Other

This product is contraindicated for individuals with any known or suspected estrogen-dependent cancer.

Storage

Storage

Storage: Keep tightly closed in a cool, dry place.

Formulation

Formula re: Contains

Estrovera's key ingredient, ERr731, has been used safely and effectively for over 20 years and is supported by clinical studies.

Formulation re: Other

Estrovera provides relief for multiple menopausal symptoms, including hot flashes, sleep disturbances, mood swings, irritability, anxiety, and sexual problems. Visit MetaDispensary.com for additional information.

Formulation re: Does NOT Contain

This product is non-GMO, gluten-free, and vegetarian.

Formulation re: Vegetarian/Vegan

This product is non-GMO, gluten-free, and vegetarian.

Formula re: Contains

Featuring ERr 731

Formula re: Type

Plant-derived menopausal hot flash relief

Formulation re: Other

Highly Efficacious Formulated with ERr 731, which has shown up to 83% reduction in menopausal symptoms

Formulation re: Other

83% decrease in daily hot flashes ERr 731 delivers non-hormonal hot flash relief, with up to an 83% decrease in daily hot flashes and other menopausal symptoms.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Seals/Symbols

GF Certified gluten-free

General Statements: All Other Content

8 7-Tablet Bottles

General Statements: All Other Content

Exceptional safety profile ERr 731 recommended by healthcare professionals in Europe since 1993

General Statements: All Other Content

Extensively studied Multiple well-designed, randomized, double-blind placebo-controlled studies

General Statements: All Other Content

This estimated ratio is not included in the publication of cumulative results of a 12-week study followed by 2 48-week observational studies (OS). It is calculated from the mean change of the MRS II total score of 5.7 at the end of the first 48-week OS divided by the baseline score of 34. There was no change in total score from the end of the first OS to the end of the second OS. These results are from the ERr 731 subgroup only, which was administered ERr 731 daily for a total of 108 weeks. This calculation does not take into account some changes in study population over time.

General Statements: All Other Content

12-week study of 112 perimenopausal women

General Statements: All Other Content

ERr 731 subjects reported a significant decrease in the median number of daily hot flashes compared to subjects taking placebo

General Statements: All Other Content

Kaszkin-Bettag M, Ventskovsky BM, Solskyy S, et al. Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms. Altern Ther Health Med. 2009; 15(1):24-34.

Manufacturer & Distributor

Distributor

Metagenics

Gig Harbor, WA, 98332

800 692 9400

Market Reference

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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Shaffer Health Center

    4.7 (17)

    Vitamin & supplements store

    Fairgrounds Market, 1825 W Chew St, Allentown, PA 18104

  • The Muscle Store

    4.7 (64)

    Vitamin & supplements store

    3805 Nazareth Pike, Bethlehem, PA 18020

  • The Vitamin Shoppe

    4.3 (75)

    Vitamin & supplements store

    2180 MacArthur Rd, Whitehall Township, PA 18052

  • Top Physique Sports Supplement Boutique

    4.0 (4)

    Vitamin & supplements store

    Blue Door & Parking face side of Valero Gas, Corp office:, 3102 Lehigh St, Allentown, PA 18103

  • Green Earth Marketplace (GEM)

    4.6 (31)

    Vitamin & supplements store

    1328 Chestnut St, Emmaus, PA 18049

  • VitaFresh

    Vitamin & supplements store

    4424 Park Ave, Slatington, PA 18080

Research & Studies

  • The quality, safety, and efficacy of botanical drugs

    K Palatini, S Komarnytsky - Botanical Drug Products, 2018 - api.taylorfrancis.com

    … In the United States, botanical products with health-related … Ⓡ) when compared to a dietary supplement (Estrovera), that was … launched in the US market by Metagenics Inc in 2010. The …

    20183 citations
  • Estrovera™

    F ERr - metagenicscanada.com

    … with ERr 731® (the main ingredient in Estrovera tablets) since its US introduction in 2009. This … of water once daily at the same time of day or as directed by your healthcare practitioner. …

  • Rheum rhaponticum extract (ERr 731): postmarketing data on safety surveillance and consumer complaints

    JL Chang, MB Montalto, PW Heger… - Integrative Medicine …, 2016 - pmc.ncbi.nlm.nih.gov

    … , is the senior director of medical affairs at Metagenics, Inc, in … US distributor of Estrovera were also collected and analyzed. … as the dietary supplement Estrovera (Metagenics, Aliso Viejo, …

    201627 citations
  • An Interview with Lisa McDonald, Metagenics Senior Director of Marketing and Medical Education.

    S Baker - Alternative Therapies in Health & Medicine, 2024 - search.ebscohost.com

    … about Metagenics, it’s really a leading health and wellness company specializing in nutritional supplements. I … The first is Estrovera featuring ERr731 that has been shown to reduce 12 …

    2024
  • Estrovera®

    MRSIIT SCORE

  • Midlife Wake-Ups, Hot Flashes, and Racing Minds: Your Guide to Better Sleep in Menopause

    J CHMIELEWSKI - jillchmielewski.com

    … our brain health, and they tend to wreak havoc on our gut health as … Let’s try to drink the bulk of our fluids earlier in the day. … Estrovera by Metagenics contains an extract of rhubarb and is …

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-03-24. DSLD Label ID: 216365. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.