5-MTHF (L-Methylfolate)none
Other CombinationsBrand: Metabolic Maintenance
Net Contents
90 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
Not specified
Supplement Form
Capsule
Bar Code (UPC/SKU)
8 38287 00532 2
Product Version
V.01
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
2 distinct active ingredients are disclosed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
1 ingredients report a %DV; 1 meet or exceed 100% DV.
Label states: Vegetarian.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| L-Methylfolate | 2.5 mg | 625% |
| from 5-Methyltetrahydrofolate | 5 mg | — |
| Glycine | 230 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
DIRECTIONS: Use only as directed by a healthcare professional.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
CAUTION: Pregnant or lactating women, or individuals taking prescription medications, consult healthcare professional before taking this product.
Precautions re: Children
Keep tightly closed in a cool, dry place out of the reach of children.
Storage
Storage
Keep tightly closed in a cool, dry place out of the reach of children.
Formulation
Formulation re: Does NOT Contain
Each preservative-free vegetarian capsule contains only the active ingredients listed on the label.
Formulation re: Does NOT Contain
Excipient-free.
FDA Statements
FDA Statement of Identity
DIETARY SUPPLEMENT
Other Label Statements
General Statements: All Other Content
532002A EXP 2/14
General Statements: All Other Content
V.01
General Statements: All Other Content
Manufactured in a GMP Certified Facility
General Statements: All Other Content
ESSENTIALS
Manufacturer & Distributor
Manufacturer
Metabolic Maintenance Products
PO Box 940, Sisters, Oregon, 97759
Market Reference
Metabolic Maintenance L-Methylfolate mg
iHerb4.7(98)$50.00Metabolic Maintenance L-Methylfolate 5mg - Gluten-free & Dairy-free Folate Supplement - Brain Supplement For Cognitive Health - Methylated Folate For
eBay - jdjovanny4.7(98)$24.65L-Methylfolate Plus Methyl-B12
Triquetra Health4.2(267)$17.99Thorne 5-MTHF 1 mg 60 Capsules
The Healthy Place4.8(2000)$24.00Rho Liposomal Methylfolate 5-MTHF + B12 Complex
Rho Nutrition4.8(75)$39.95365 by Whole Foods Market Methyl Folate 100 Count
Whole Foods Market$9.79Lowest5 Methylfolate 5-mthf L-Methylfolate 5 mg
methyl-life.com4.7(42)$44.00Xymogen 5-MTHF Capsules
Milltown Pharmacy4.7(7)$32.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
GNC
4.7 (103)Vitamin & supplements store
16039 Conneaut Lake Rd, Meadville, PA 16335
Research & Studies
Comparative Analysis of Treatment With Folate Forms in Clinical Practice
O Skavinska, Z Rossokha, V Stefanyshyn… - Nutrition …, 2025 - academic.oup.com
… The liver prioritizes sFA metabolism but has lower affinity for 5-MTHF, allowing some to enter … 677TT is a risk factor, and 5-MTHF supports healthy offspring in subfertile individuals. …
20251 citationsImpact of supplementation and nutritional interventions on pathogenic processes of mood disorders: A review of the evidence
CT Hoepner, RS McIntyre, GI Papakostas - Nutrients, 2021 - mdpi.com
… activity with L-methylfolate and SAMe supplementation in … of a methyl group from 5-MTHF, which then forms methionine and … suggests that medical foods, particularly L-methylfolate and …
202180 citations13 Natural Medications in Psychiatry
FA Smith, D Mischoulon - Massachusetts General Hospital …, 2015 - books.google.com
… • Complementary and alternative medical therapies are … of 5-methyl tetrahydrofolate (5-MTHF; Deplin) supports its efficacy … L-methylfolate as adjunctive therapy for SSRI-resistant major …
2015Methylenetetrahydrofolate reductase screening in treatment-resistant depression
CCE Kandler, MAJST Lam - Federal Practitioner, 2019 - pmc.ncbi.nlm.nih.gov
… 5-MTHF then … metabolism, L-methylfolate supplementation has been recommended. In a 60-day randomized trial of a selective serotonin reuptake inhibitor (SSRI) and L-methylfolate vs …
201910 citationsApplied Evidence
BS Linn, T Mahvan, BEY Smith, AB Oung - community.the-hospitalist.org
Marcelo G* is a 46-year-old man who presented to our family medicine clinic with a complex medical history including end-stage renal disease (ESRD) and hemodialysis, chronic …
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-08-23. DSLD Label ID: 24706. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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