5-HTP 50 mg®

Other Combinations

Brand: Metabolic Maintenance

CapsuleOther CombinationsOn Market
Click to view full label

Net Contents

60 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

60

Supplement Form

Capsule

Bar Code (UPC/SKU)

8 38287 00100 3

Product Version

V-18

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

3Active Ingredients

3 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Milk
  • Egg
  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Capsule(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Vitamin B63 mg176%
Pyridoxal 5-Phosphate5 mg
5-HTP50 mg
Glycine220 mg

Not Present

Other Ingredients

Vegetarian Cellulose Capsule

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

All Other

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: One (1) capsule daily, or as directed by a healthcare professional. Best taken between meals or at bedtime.

Warnings & Precautions

Precautions re: All Other

Caution: Do not take with MAO inhibitors or tricyclic antidepressants.

Precautions re: Pregnant or Nursing or Prescription Medications

Pregnant or lactating women, consult your healthcare professional before taking this product.

Precautions re: Children

Keep tightly closed in a cool, dry place, out of the reach of children.

Storage

Storage

Keep tightly closed in a cool, dry place, out of the reach of children.

Formulation

Formulation re: Does NOT Contain

Egg free Gluten free Free of nuts Dairy free

Formulation re: Other

Manufactured in a GMP Compliant Facility

FDA Statements

FDA Statement of Identity

Dietary Supplement

Manufacturer & Distributor

Manufacturer

Metabolic Maintenance

601 N Larch Street, Sisters, Oregon, 97759

800-772-7873

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Research & Studies

  • The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine

    N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com

    … The kynurenine and 5-HT pathways are two main metabolic routes for Trp metabolism in … , plays a key role in the conversion of Trp to 5-hydroxytryptophan (5-HTP) [1,35]. 5-HT is rapidly …

    2021272 citations
  • The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial

    S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com

    … and mental health regulation [21,23,24,25]. Given that the participants in this study were cognitively healthy and had not previously taken 5-HTP supplementation, 100 mg was selected …

    20255 citations
  • GTP-cyclohydrolase deficiency responsive to sapropterin and 5-HTP supplementation: relief of treatment-refractory depression and suicidal behaviour

    L Pan, BW McKain, S Madan-Khetarpal… - Case …, 2011 - casereports.bmj.com

    … mg orally twice daily and carbidopa 25 mg daily was added. 5-HTP was started at 50 mg and titrated to 200 mg, the patient had normal sleep duration and continuity, and at 250 mg, he …

    201139 citations
  • Adjunctive 5-hydroxytryptophan slow-release for treatment-resistant depression: clinical and preclinical rationale

    …, AD Krystal, KRR Krishnan, MG Caron - Trends in …, 2016 - cell.com

    … 5-HTP metabolism in the intestine and liver is three and seven times slower, respectively, … Such slower metabolism could account for the longer human T 1/2 observed of 5-HTP (2h) …

    201699 citations
  • Metabolic Correction and Depression: Effect of a Supplement Combination

    M González, J Rodríguez, C Rocha… - Ciencias de la …, 2020 - cienciasdelaconducta.org

    … Patients received the combination supplement consisting of … supplement formula included: 5-hydroxytryptophan (5-HTP) … Intestinal absorption of 5-HTP does not require the presence of …

    20201 citations
  • 5-HTP: The natural way to overcome depression, obesity, and insomnia

    M Murray - 1999 - books.google.com

    … 5-HTP can influence brain and body chemistry, I recommend that it be used under medical … the safety and efficacy of 5-HTP, it is not intended to provide medical advice or to substitute …

    199933 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-09-22. DSLD Label ID: 273943. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.