SAM-e 1000 mgnone

Non-Nutrient / Non-Botanical

Brand: Mental Refreshment

CapsuleNon-Nutrient/Non-BotanicalOn Market

Functions

Sleep, Mood & Stress

Product label for SAM-e 1000 mg — Click to view full label

Net Contents

90 Capsule(s)

Serving Size

4 Capsule(s)

Servings Per Container

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 138073 751338

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

Milk
Wheat
Soy
Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 4 Capsule(s) · 1 per day

Ingredient	Amount Per Serving
SAM-e(S-Adenosyl-L-Methionine Disulfate Tosylate)	1000 mg	—

Not Present

Other Ingredients

GelatinRice powder

Target Groups

Adult (18 - 50 Years)Gluten FreeDairy FreeSugar Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: For adults, take four (4) capsules daily preferably with a meal.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Precautions re: All Other

Discontinue use and consult your doctor if any adverse reactions occur.

Precautions re: Children

Not intended for use by persons under the age of 18. Keep out of reach of children.

Storage

Store in a dry place and avoid excessive heat.

Formulation

Formulation re: Does NOT Contain

Contains No: Artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Formula re: Contains

S-adenosyl-methionine disulfate tosylate 1000 mg per serving

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Premium Brand / Optimum Results

General Statements: All Other Content

100% Satisfaction Guaranteed

Seals/Symbols

Made in the USA GMP Good Manufacturing Practice Consistent Quality Manufactured in a FDA Registered facility that conforms to GMP standards.

Manufacturer & Distributor

Distributor

Mental Refreshment Nutrition

Severna Park, MD, 21146

Market Reference

$8.97 – $85.95· 19 listings

SAM-e 1000mg Per Tablet, 60 Servings of Pharmaceutical Grade, Non-GMO, Soy Free, Gluten Free, and Enteric Coated Tablets
eBay - baversports
$40.99
Sam E 1000mg High Potency Anxiety Relief Mood Liver & Joint 120 Caps
eBay - goodsfromny1.0(1)
$18.95
Pure Encapsulations SAMe 60 Capsules
Pure For You4.4(70)
$84.50
Sam-e -1000mg - Supports Joint Comfort And Brain Health 30 - 120
eBay - good-health-5791.0(1)
$10.56
Bcuelov SAM-e 1000mg Per Serving Supports Liver Health Joint Comfort Mood Balance 120 Capsules
Walmart - Bcuelov
$14.39
1000mg Sam-e - Supports Mood, Brain, Joint Comfort And Health
eBay - ertdfg2-65
$47.90
BrainMD SAMe Mood & Movement 400 Tablets
iHerb4.4(122)
$59.95
Sam-e 1000mg, High Potency Anxiety Relief Mood Liver & Joint 5x120
eBay - goodsfromny1.0(1)
$85.95

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Nutrition Depot
4.5 (13)
Vitamin & supplements store
5900 Spout Springs Rd Ste h8, Flowery Branch, GA 30542
Directions (770) 965-3268
Nutrition Depot
4.9 (41)
Vitamin & supplements store
2095 GA Hwy 211, Braselton, GA 30517
Directions (770) 868-1401
Marati Wellness | Black Seed Oil, Sea Moss, Moringa Leaf, Colloidal Silver Supplements Store
5.0 (15)
Vitamin & supplements store
3300 Hamilton Mill Rd Ste 102 #535, Buford, GA 30519
Directions (404) 999-1007
Your CBD Store | SUNMED - Flowery Branch, GA
5.0 (580)
Vitamin & supplements store
5887 Spout Springs Rd D402, Flowery Branch, GA 30542
Directions (678) 828-7517
Health
5.0 (2)
Store
940 Sherwin Pkwy Ste 100, Buford, GA 30518
Directions (800) 312-1605
The Vitamin Shoppe
4.3 (218)
Vitamin & supplements store
3226 Buford Dr, Buford, GA 30519
Directions (770) 904-5964
The B-12 Store
4.9 (311)
Vitamin & supplements store
Located in: Mall of Georgia, 3333 Buford Dr Ste 1099, Buford, GA 30519
Directions (678) 765-2820
GNC
4.0 (41)
Vitamin & supplements store
3333 Buford Dr Spc 2071, Buford, GA 30519
Directions (678) 482-4473

Research & Studies

Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-l-methionine (SAM-e), … Controlled trials have found SAM-e to be more efficacious than …
2009178 citations
Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms
H Kunugi - Psychiatry and clinical neurosciences, 2023 - Wiley Online Library
… (SAM-e), donates the methyl group in the cycle. There is evidence based on a meta-analysis that SAM-e … Nonetheless, in Europe, SAM-e is used as a prescription drug, and, in North …
2023135 citations
Ten Steps to Take Charge of Your Emotional Life Overcoming Anxiety, Distress, and Depression Through Whole-person Healing
EA Wood - 2006 - books.google.com
… emotional health, integrating the best of holistic therapies with sound allopathic medical … with what have traditionally been daunting mental-health challenges. A wonderful resource for …
20063 citations
Performance Lab Sleep Review 2026: 90-Night Oura Data & Honest Verdict
M Reid - ultimatestrengths.com
… dosing (500 mg–1,000 mg) has been used in some studies. … Doses in research typically range from 250 mg to 1,000 mg. … If you’ve had reactions to 5-HTP or SAM-e supplements, start …
Microdosing Psychedelics to Improve Mood: A Randomized Clinical Trial
N Farb - assets-eu.researchsquare.com
… will be evaluated by the research team and will include acetaminophen, non-steroidal anti-inflammatory drugs, and common doses of vitamins and minerals with the exception of SAM-e…
LLM-Augmented Therapy Normalization and Aspect-Based Sentiment Analysis for Treatment-Resistant Depression on Reddit
Y Zhu, S Lakamana, M Rouhizadeh, S Bozkurt… - arXiv preprint arXiv …, 2026 - arxiv.org
… We collected posts from 28 mental health-related subreddits between 2010 and July 2025, spanning general depression communities, treatment- and medication-focused forums, and …
2026

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-05-22. DSLD Label ID: 247682. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.