SAMe 400 mg®
Non-Nutrient / Non-BotanicalBrand: Life Extension
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Enteric Coated Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 37870 19333 3
Product Version
QE01933D
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Non-GMO.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Enteric Coated Tablet(s) · 1–3 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl-Methionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: Take one (1) tablet one to three times daily in divided doses, preferably on any empty stomach, or as recommended by a healthcare practitioner. Take with co-factors vitamins B12, B6, and folic acid.
Warnings & Precautions
Precautions re: All Other
Caution: SAMe should not be taken by those diagnosed with bipolar disorder.
Precautions re: Children
Warnings Keep out of reach of children.
Precautions re: All Other
Do not exceed recommended dose. Do not purchase if foil is broken or damaged.
Precautions re: Pregnant or Nursing or Prescription Medications
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Storage
Storage
Store in a cool dry place.
Formulation
Formula re: Contains
S-Adenosyl-Methionine
Formulation re: Does NOT Contain
Non-GMO
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
SAMe has multiple mechanisms of action that are used throughout the body
General Statements: All Other Content
Brain and Mood SAMe boosts brain cell methylation and facilitates youthful DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters such as norepinephrine, dopamine, and seratonin and may account for SAMe’s mood-elevating properties. SAMe also helps maintain acetylcholine levels which are necessary for cognitive function.
General Statements: All Other Content
Liver and Detox In order to perform its detoxification role, the liver continually performs large numbers of complex enzymatic reactions. SAMe facilitates healthy methylation enzymatic processes and boosts hepatic levels of glutathione, a critical antioxidant.
General Statements: All Other Content
Joint SAMe may help to ease inflammation and can support healthy joint mobility and function without side effects.
General Statements: All Other Content
Supports joints and emotional well-being
General: Product/Version Code
QE01933D
General Statements: All Other Content
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Manufacturer & Distributor
Distributor
Quality Supplements and Vitamins, Inc.
Ft. Lauderdale, FL, 33309
1-866-280-2852
Market Reference
Life Extension SAMe 400mg 60 pcs
Professional Supplement Center4.8(633)$52.99Life Extension Natural Softgels
Life Extension4.8(837)$18.75Life Extension SAMe (Disulfate Tosylate) 400 mg 30 Enteric Coated Tablets
GoSupps.com4.8(653)$264.99Jarrow Formulas SAM-e 400 60 Tablets
Life Extension4.7(442)$38.99Nature Made SAM-e Complete 400 mg
Walmart4.5(310)$53.98NOW Foods SAMe 400 mg 30 Tablets
Target4.7(414)$30.99Life Extension Extend-Release Magnesium
Life Extension4.8(933)$9.75Life Extension Bone Restore Calcium Supplement with Vitamin K2
Walmart4.8(4000)$17.97
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.5 (166)Vitamin & supplements store
1313 York Rd, Lutherville, MD 21093
GNC
4.3 (18)Vitamin & supplements store
58 Cranbrook Rd, Cockeysville, MD 21030
The Vitamin Shoppe
4.3 (158)Vitamin & supplements store
9404 Reisterstown Rd, Owings Mills, MD 21117
GNC
3.4 (41)Vitamin & supplements store
9908 Reisterstown Rd, Owings Mills, MD 21117
GNC
4.0 (24)Vitamin & supplements store
8950 Waltham Woods Rd, Parkville, MD 21234
The Vitamin Shoppe
4.3 (171)Vitamin & supplements store
6026 Baltimore National Pike, Catonsville, MD 21228
The Vitamin Shoppe
4.5 (82)Vitamin & supplements store
3719 Boston St, Baltimore, MD 21224
GNC
4.2 (56)Vitamin & supplements store
5810 Baltimore National Pike Space #A-8, Baltimore, MD 21228
Research & Studies
Antiaging agents: safe interventions to slow aging and healthy life span extension
JK Liu - Natural products and bioprospecting, 2022 - Springer
… opportunity for the healthcare and pharmaceutical industries. … slow aging and healthy life span extension of natural products … healthy aging and the potential role of life span extension …
2022112 citationsLife Extension Prescribing Data and Outcomes Signals: What the Evidence Actually Shows
BBB Standing - healthrx.com
… labeling with the FDA under Dietary Supplement Health and Education Act (DSHEA) rules. … same federal inspection schedule. Patients receiving Rx compounds through Life Extension's …
Antioxidant vitamins and mineral supplementation, life span expansion and cancer incidence: a critical commentary
P Dolara, E Bigagli, A Collins - European journal of nutrition, 2012 - Springer
… in 1996 by the Physicians’ Health Study (PHS) [67], with the same dosage of β-carotene … (published in 2000) on 9,541 subjects administered 400 mg vitamin E for 4.5 years, followed for …
201290 citationsLifespan effects of simple and complex nutraceutical combinations fed isocalorically to mice
SR Spindler, PL Mote, JM Flegal - Age, 2014 - Springer
… This contained 1,000 mg of acetyl-l-carnitine, 400 mg of α-… The concentrations of Bone Restore plus K2, Life Extension … dietary supplements do not provide the same lifespan and health …
201429 citationsStartling findings about vitamin D levels in Life Extension® members
W Faloon - Life Extension Magazine, 2010 - davidcenter.com
… medical community who think that supplementing with less than 1,000 IU a day of vitamin D is adequate. To the contrary, even Life Extension… results were less than or equal to 50 ng/mL. …
20109 citationsThe future of aging: pathways to human life extension
GM Fahy, M West, LS Coles, SB Harris - 2010 - books.google.com
… At the same time, a tidal wave of aging post World War II baby … in good health until we get to the “tipping point” in life extension. … You would need to supplement with about 400–700 mg a …
201067 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-05-24. DSLD Label ID: 74299. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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