SAMe 400 mg®
Non-Nutrient / Non-BotanicalBrand: Life Extension
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 37870 21763 3
Product Version
Pkg02176B
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Non-GMO.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Tablet(s) · 2–3 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl-Methionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: Take one (1) tablet two to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. Take with co-factors vitamins B12, B6, and folic acid.
Warnings & Precautions
Precautions re: All Other
Caution: SAMe should not be taken by those diagnosed with bipolar disorder.
Precautions re: Children
Warnings: Keep out of reach of children.
Precautions re: All Other
Do not exceed recommended dose. Do not purchase if foil is broken or damaged.
Precautions re: Pregnant or Nursing or Prescription Medications
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Precautions re: All Other
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Storage
Storage
Store in a cool dry place.
Formulation
Formula re: Contains
SAMe has multiple mechanisms of action that are used throughout the body Brain and Mood SAMe boosts brain cell methylation and facilitates youthful DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters such as norepinephrine, dopamine, and serotonin and may account for SAMe’s mood-elevating properties. SAMe also helps maintain acetylcholine levels which are necessary for cognitive function. Liver and Detox In order to perform its detoxification role, the liver continually performs large numbers of complex enzymatic reactions. SAMe facilitates healthy methylation enzymatic processes and boosts hepatic levels of glutathione, a critical antioxidant. Joint SAMe may help to ease inflammation and can support healthy joint mobility and function without side effects.
Formula re: Contains
S-Adenosyl-Methionine
Formulation re: Does NOT Contain
Non GMO LE Certified
Formulation re: Other
Supports joints and emotional well-being
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
Non GMO LE Certified
Manufacturer & Distributor
Distributor
Quality Supplements and Vitamins, Inc.
Ft. Lauderdale, FL, 33309
1-866-280-2852
Market Reference
Life Extension SAMe 400mg 60 pcs
Professional Supplement Center4.8(633)$52.99Life Extension Natural Softgels
Life Extension4.8(837)$18.75Jarrow Formulas SAM-e 400 60 Tablets
Life Extension4.7(442)$38.99Life Extension SAMe (Disulfate Tosylate) 400 mg 30 Enteric Coated Tablets
GoSupps.com4.8(653)$264.99Life Extension Extend-Release Magnesium
Life Extension4.8(933)$9.75Nature Made SAM-e Complete 400 mg
Walmart4.5(310)$53.98Life Extension Mix Capsules 360
Life Extension4.8(403)$58.50NOW Foods SAMe 400 mg 30 Tablets
Vitacost.com4.7(414)$28.16
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
GNC
3.9 (36)Vitamin & supplements store
400 SW 29th St, Topeka, KS 66611
The Vitamin Shoppe
4.5 (146)Vitamin & supplements store
11821 Metcalf Ave, Overland Park, KS 66210
Walgreens
3.5 (121)Drug store
1001 SW Topeka Blvd, Topeka, KS 66612
The Vitamin Shoppe
4.5 (97)Vitamin & supplements store
9 W 62 Terrace, Kansas City, MO 64113
GNC
4.4 (25)Vitamin & supplements store
15810 Shawnee Mission Pkwy Spc e, Shawnee, KS 66217
The Vitamin Shoppe
4.3 (127)Vitamin & supplements store
8948 NW Skyview Ave 1700 T.S.M.C, Kansas City, MO 64154
GNC
4.2 (57)Vitamin & supplements store
4025 Mill Street Britton, Kansas City, MO 64111
GNC
3.9 (49)Vitamin & supplements store
1803 Village West Pkwy Ste m-109, Kansas City, KS 66111
Research & Studies
Antiaging agents: safe interventions to slow aging and healthy life span extension
JK Liu - Natural products and bioprospecting, 2022 - Springer
… opportunity for the healthcare and pharmaceutical industries. … slow aging and healthy life span extension of natural products … healthy aging and the potential role of life span extension …
2022112 citationsLife Extension Prescribing Data and Outcomes Signals: What the Evidence Actually Shows
BBB Standing - healthrx.com
… labeling with the FDA under Dietary Supplement Health and Education Act (DSHEA) rules. … same federal inspection schedule. Patients receiving Rx compounds through Life Extension's …
The Life Extension Revolution: The New Science of Growing Older Without Aging
PL Miller, M Reinagel - 2007 - books.google.com
… the Life Extension Foundation invited me to join its medical … These are the same therapies and protocols that have … people over the age of 40 can benefit from DHEA supplementation. …
200710 citationsAntioxidant vitamins and mineral supplementation, life span expansion and cancer incidence: a critical commentary
P Dolara, E Bigagli, A Collins - European journal of nutrition, 2012 - Springer
… in 1996 by the Physicians’ Health Study (PHS) [67], with the same dosage of β-carotene … (published in 2000) on 9,541 subjects administered 400 mg vitamin E for 4.5 years, followed for …
201290 citationsLifespan effects of simple and complex nutraceutical combinations fed isocalorically to mice
SR Spindler, PL Mote, JM Flegal - Age, 2014 - Springer
… This contained 1,000 mg of acetyl-l-carnitine, 400 mg of α-… The concentrations of Bone Restore plus K2, Life Extension … dietary supplements do not provide the same lifespan and health …
201429 citationsStartling findings about vitamin D levels in Life Extension® members
W Faloon - Life Extension Magazine, 2010 - davidcenter.com
… medical community who think that supplementing with less than 1,000 IU a day of vitamin D is adequate. To the contrary, even Life Extension… results were less than or equal to 50 ng/mL. …
20109 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-08-23. DSLD Label ID: 232840. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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