SAMe 200 mg S-Adenosyl-Methionine
Non-Nutrient / Non-BotanicalBrand: Life Extension
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
Not specified
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 37870 21753 4
Product Version
Not specified
Suggested Use
Directions: Take one (1) tablet two to six times daily in divided doses; preferably on an empty stomach; or as recommended by a healthcare practitioner. Take with co-factors vitamins B12; B6; and folic acid.
Market Reference
Life Extension SAMe 200 mg 30 Tablets
Herbs Direct4.8(798)$20.25Life Extension Two-Per-Day
Life Extension4.8(37000)$9.94LowestLife Extension SAMe 400 mg 30 Enteric Coated Tablets
Village Green Apothecary4.8(1200)$27.74Nature's Craft SAM-e 200 mg Capsules
Target4.8(269)$20.15Life Extension Once-Daily Health Booster Softgels
Life Extension4.7(414)$43.50Life Extension Mix Tablets 240 Tablets
Life Extension4.8(786)$55.50Life Extension EnergyGain , 200 mg, 30 vegetarian capsules
Life Extension4.4(157)$27.00Life Extension Senolytic Activator 36 Capsules
Life Extension4.7(1400)$20.25
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.2 (79)Vitamin & supplements store
4041 W Division St, St Cloud, MN 56301
Midwest Vitamins LLC
5.0 (3)Vitamin & supplements store
20750 Rogers Dr Ste c, Rogers, MN 55374
Research & Studies
S‐Adenosyl methionine in the therapy of depression and other psychiatric disorders
N Karas Kuželički - Drug development research, 2016 - Wiley Online Library
… to healthy individuals with the same genotype. … 200 mg/day), with the exception of one that used 1,600 mg/day PO. The trials indicated that the minimum SAM therapeutic dose is 400 mg/…
201637 citationsS-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial.[ISRCTN36233495]
WI Najm, S Reinsch, F Hoehler, JS Tobis… - BMC musculoskeletal …, 2004 - Springer
… -L-Methionine (SAMe) used in this study was enteric coated 200 mg tablets from 400 mg S-… , pain, change in health, overall health, social support, and quality of life. All nine items used …
2004213 citationsS-adenosylmethionine
T Bottiglieri, PL Gerbarg, RP Brown - … and Integrative Treatments …, 2017 - books.google.com
… In every living cell, SAMe synthesis entails condensation of … patients should start at 200 mg/day, titrating upward slowly. … and alleviation by S-adenosyl methionine. J Neurochem 110 (3): …
20179 citationsExcess S-adenosylmethionine inhibits methylation via catabolism to adenine
K Fukumoto, K Ito, B Saer, G Taylor, S Ye… - Communications …, 2022 - nature.com
… supplement (manufactured as SAMe or SAM-e) to promote emotional well-being and healthy … Is S-adenosyl methionine (SAMe) for depression only effective in males? A re-analysis of …
202256 citationsS-Adenosyl-l-Methionine Alleviates the Senescence of MSCs Through the PI3K/AKT/FOXO3a Signaling Pathway
L Shang, X Li, X Ding, G Liu, Z Pan, X Chen… - Stem Cells, 2024 - academic.oup.com
… the reaction was terminated by adding an equal volume of PBS. The … span in mice and health span in monkeys. As an important … S-Adenosyl methionine regulates calcium channels and …
202413 citationsTreatment of Depression: Roles of S-Adenosyl-L-Methionine and Folate
JE Alpert, GI Papakostas - Natural medications for psychiatric …, 2008 - books.google.com
… -being as well as joint health, SAMe has been the subject of … low-dose folate supplementation (200 mg) that was accompanied … S-Adenosyl-methionine in depression: a comprehensive …
200824 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-08-23. DSLD Label ID: 232841. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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