Pro-Resolving Mediators®

Fats & Fatty Acids

Brand: Life Extension

Softgel CapsuleFat/Fatty AcidOn Market
Click to view full label

Net Contents

30 Softgel(s)

Serving Size

1 Softgel(s)

Servings Per Container

30

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 37870 22233 0

Product Version

L02223E

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

4Active Ingredients

4 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2% Daily Value Coverage

2 ingredients report an established %DV per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Softgel(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Calories5 Calorie(s)—
Total Fat0.5 Gram(s)1%
Cholesterol< 5 mg2%
Marine Lipid Concentrate500 mg—
Pro-resolving Mediators300 mcg—
18-Hydroxy-Eicosapentaenoic Acid——
17-Hydroxy-Docosahexaenoic Acid——
14-Hydroxy-Docosahexaenoic Acid——

% Daily Values are based on a 2,000 Calorie Diet.

Other Ingredients

Highly Refined Marine Oil ConcentrateGelatinOlive OilGlycerinWater, PurifiedLemon FlavorMixed Tocopherols

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: Take one (1) softgel daily, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: All Other

Read the entire label and follow the directions carefully prior to use.

Precautions re: Children

Warnings: Keep out of reach of children.

Precautions re: All Other

Do not exceed recommended dose. Do not purchase if outer seal is damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Precautions re: All Other

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Storage

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Gluten free Non GMO Le certified

Formulation re: Other

Remove Restore Renew

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Scan for product info

Seals/Symbols

Non GMO Le certified

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$18.00 – $238.71· 17 listings
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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Supplement Warehouse Retail Store

    4.6 (1281)

    Vitamin & supplements store

    7110 W Greenfield Ave, West Allis, WI 53214

  • Nutricion & Bienestar

    5.0 (66)

    Vitamin & supplements store

    1734 W Greenfield Ave, Milwaukee, WI 53204

  • GNC

    3.6 (73)

    Vitamin & supplements store

    2155 Miller Park Way, Milwaukee, WI 53219

  • The Vitamin Shoppe

    4.3 (165)

    Vitamin & supplements store

    7515 W Layton Ave, Milwaukee, WI 53220

  • MMSUPPS Supplements & Smoothies

    4.7 (124)

    Vitamin & supplements store

    8635 S Howell Ave, Oak Creek, WI 53154

Research & Studies

  • Pro-resolving lipid mediators in diseases: exploring the molecular basis and clinical implication

    C Li, Z Wang, Y Yang, Q Jiang, Y Jiang, J Xiao… - Molecular …, 2026 - Springer

    … Recent studies have demonstrated that PRLMs regulate inflammation through specialized pro-resolving programs, such as enhancing efferocytosis, modulating cytokine networks, …

    20265 citations
  • Specialized pro-resolving mediator network: an update on production and actions

    N Chiang, CN Serhan - Essays in Biochemistry, 2020 - portlandpress.com

    … These are significant public health concerns, thus emphasizing the urgent need to … , demonstrating pro-resolving actions of anabasum [30]. With young adults taking ω-3 supplements, …

    2020480 citations
  • Role of specialized pro-resolving mediators on inflammation, cardiometabolic health, disease progression, and quality of life after omega-3 PUFA supplementation …

    S Jannas-Vela, AA Candia, L Peñailillo… - …, 2023 - pmc.ncbi.nlm.nih.gov

    … supplementation and AEx training on disease progression, cardiometabolic health, and quality of life, and … fluid levels of specialized pro-resolving mediators (SPMs) in subjects with RA. …

    20237 citations
  • Synbiotic Compositions of Bacillus megaterium and Polyunsaturated Fatty Acid Salt Enable Self-Sufficient Production of Specialized Pro-Resolving Mediators

    B Speckmann, J Kleinbölting, F Börner, PM Jordan… - Nutrients, 2022 - mdpi.com

    … n-3 PUFA supplementation strategies, we devised a … as crucial mediators of their beneficial health effects, in particular … [31], and also extending to inflammatory bowel diseases, asthma, …

    202210 citations
  • Can specialized pro-resolving mediators deliver benefit originally expected from fish oil?

    MD Rosenthal, J Patel, K Staton, RG Martindale… - Current …, 2018 - Springer

    … health [1]. The results of this meta-analysis, as well as several others, sidelined the supplementation of … of SPMs were shown to decrease local expansion of the abdominal aorta …

    201820 citations
  • Specialized pro-resolving mediators: It's anti-oxidant stress role in multiple disease models

    F Wang, S Huang, H Xia, S Yao - Molecular immunology, 2020 - Elsevier

    … Recently, considerable attention has been focused on specialized pro-resolving mediators(SPMs). SPMs are endogenous mediators derived from polyunsaturated fatty acids, which …

    202019 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-05-21. DSLD Label ID: 328645. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.