Optimized Tryptophan Plus

Botanicals with Nutrients

Brand: Life Extension

CapsuleOn Market
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Net Contents

90 Vegetarian Capsule(s)

Serving Size

3 Vegetarian Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 37870 17219 2

Product Version

Not specified

Suggested Use

Directions: Take three (3) capsules all at once before bedtime; or one capsule on an empty stomach before each meal; or as recommended by a healthcare practitioner. Best if taken separately from protein or amino acids.

Market Reference

$20.38 – $32.00· 8 listings
  • Life Extension Tryptophan Plus Capsules

    iHerb4.6(626)
    $24.00
  • Life Extension L- Tryptophan 500 mg 90 Capsules

    Life Extension4.7(496)
    $24.75
  • Optimized Tryptophan Plus

    Pure Prescriptions4.6(626)
    $32.00
  • Life Extension Enhanced Stress Relief 30 Capsules

    Life Extension4.6(426)
    $21.00
  • Tryptophan plus and Tryptophan with melatonin pack

    Naturitas
    $29.07
  • Tryptophan

    Sarasota IV Lounge
    $25.00
  • Tryptophan New

    biotikon.eu
    $20.38Lowest
  • Aminoplus Tryptophan plus Kapseln

    apohealth.de5.0(2)
    $28.08

Where to Buy Locally

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Research & Studies

  • Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan?

    HM Brown-Borg, R Buffenstein - Ageing research reviews, 2017 - Elsevier

    … health- and lifespan and the mechanisms involved. Rodent diets containing either lower methionine content, or tryptophan… restricted intake of methionine and tryptophan are due to their …

    201784 citations
  • Exercise training restores longevity‐associated tryptophan metabolite 3‐hydroxyanthranilic acid levels in middle‐aged adults

    N Joisten, M Reuter, F Rosenberger… - Acta …, 2025 - Wiley Online Library

    … enzymes as potential targets for healthy aging or lifespan extension, such as tryptophan 2,3-… supplementation investigated in the mouse model was more effective in lifespan extension …

    20253 citations
  • L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications

    DM Richard, MA Dawes, CW Mathias… - … of Tryptophan …, 2009 - journals.sagepub.com

    … -tryptophan, particularly L-tryptophan depletion, and on clinical trials that have been conducted using L-tryptophan supplementation. … changes in healthy adults, tryptophan depletion has …

    2009967 citations
  • Analysis, nutrition, and health benefits of tryptophan

    M Friedman - International Journal of Tryptophan Research, 2018 - journals.sagepub.com

    … For example, it has been reported that the dietary supplementation of tryptophan to healthy adults (n = 35) for the study period did not result in significant changes in serum cytokine …

    2018398 citations
  • Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management

    AC Chehadi, E Pereira de Lima… - International Journal of …, 2026 - mdpi.com

    … and glial function, further linking gut health to brain plasticity and cognition [… supplementation [291,292]. By juxtaposing data from acute Trp depletion, non-plant derived supplementation…

    20265 citations
  • Nutritional importance of tryptophan for improving treatment in depression and diabetes

    DJ Haleem - 2023 - academic.oup.com

    … The importance of tryptophan supplementation for … for the optimal physiological and mental functions of our body, where bioactive metabolites of tryptophan help improve human health. …

    202314 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-04-24. DSLD Label ID: 328618. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.