Optimized Tryptophan Plus®
Botanicals with NutrientsBrand: Life Extension
Net Contents
90 Vegetarian Capsule(s)
Serving Size
1–3 Vegetarian Capsule(s)
Servings Per Container
30
Supplement Form
Capsule
Bar Code (UPC/SKU)
7 37870 17219 2
Product Version
L01721F
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
4 distinct active ingredients are disclosed in Supplement Facts.
Label includes a proprietary blend, so some individual amounts are not itemized.
1 ingredients report a %DV; 1 meet or exceed 100% DV.
Label states: Non-GMO.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1–3 Vegetarian Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Niacin(Niacinamide) | 66 mg | 413% |
| L-Tryptophan | 1000 mg | — |
| L-Lysine(L-Lysine Hydrochloride) | 250 mg | — |
| Proprietary Tryptophan Plus Blend | 285 mg | — |
| Perluxan Hops standardized extract | — | — |
| Rosemary standardized extract | — | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Read the entire label and follow the directions carefully prior to use. Directions: Take up to three (3) capsules all at once before bedtime, or one capsule on an empty stomach before each meal, or as recommended by a healthcare practitioner. For maximum absorption take with a small amount of carbohydrate, such as diluted juice. Best if taken separately from protein or amino acids.
Warnings & Precautions
Precautions re: All Other
Caution: Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms.
Precautions re: Pregnant or Nursing or Prescription Medications
Because tryptophan may have numerous drug interactions (most commonly, MAOIs and SSRIs) consult your healthcare provider before taking this product if you are taking prescription medications.
Precautions re: All Other
Do not use before driving or operating heavy machinery.
Precautions re: Children
Warnings: Keep out of reach of children.
Precautions re: All Other
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
Precautions re: Pregnant or Nursing or Prescription Medications
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Precautions re: All Other
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Storage
Storage
Store tightly closed in a cool, dry place.
Formulation
Formulation re: Does NOT Contain
Non GMO LE Certified
Formulation re: Other
Sleep enhancement and stress reduction
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
Perluxan is used by permission.
Seals/Symbols
Non GMO LE Certified
Manufacturer & Distributor
Distributor
Quality Supplements and Vitamins, Inc.
Ft. Lauderdale, FL, 33309
1-866-280-2852
Market Reference
Life Extension Tryptophan Plus Capsules
iHerb4.6(626)$24.00
Life Extension L- Tryptophan 500 mg 90 Capsules
Life Extension4.7(496)$24.75
Optimized Tryptophan Plus
Pure Prescriptions4.6(626)$32.00
Life Extension Enhanced Stress Relief 30 Capsules
Life Extension4.6(426)$21.00
Tryptophan plus and Tryptophan with melatonin pack
Naturitas$29.07
Tryptophan
Sarasota IV Lounge$25.00
Tryptophan New
biotikon.eu$20.40
Aminoplus Tryptophan plus Kapseln
apohealth.de5.0(2)$28.11
Where to Buy Locally
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N101
5.0 (419)Vitamin & supplements store
6252 Romaine St, Los Angeles, CA 90038
MyVites
5.0 (1)Vitamin & supplements store
4645 Hollywood Blvd #1, Los Angeles, CA 90027
Peter Gillham's Nutrition Center
4.3 (16)Vitamin & supplements store
4873 Fountain Ave, Los Angeles, CA 90029
Get Yok'd Nutrition
4.9 (262)Vitamin & supplements store
3218 Galleria Way, Glendale, CA 91210
LFTR SUPPLEMENTS
5.0 (20)Vitamin & supplements store
2421 Yates Ave, Commerce, CA 90040
H CLUB
5.0 (92)Vitamin & supplements store
808 S Vermont Ave, Los Angeles, CA 90005
Route 66 Sports Nutrition
4.6 (31)Vitamin & supplements store
8529 Santa Monica Blvd, West Hollywood, CA 90069
The Vitamin Shoppe
4.4 (246)Vitamin & supplements store
101 N Fairfax Ave, Los Angeles, CA 90036
Research & Studies
Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan?
HM Brown-Borg, R Buffenstein - Ageing research reviews, 2017 - Elsevier
… health- and lifespan and the mechanisms involved. Rodent diets containing either lower methionine content, or tryptophan… restricted intake of methionine and tryptophan are due to their …
201784 citationsExercise training restores longevity‐associated tryptophan metabolite 3‐hydroxyanthranilic acid levels in middle‐aged adults
N Joisten, M Reuter, F Rosenberger… - Acta …, 2025 - Wiley Online Library
… enzymes as potential targets for healthy aging or lifespan extension, such as tryptophan 2,3-… supplementation investigated in the mouse model was more effective in lifespan extension …
20253 citationsL-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications
DM Richard, MA Dawes, CW Mathias… - … of Tryptophan …, 2009 - journals.sagepub.com
… -tryptophan, particularly L-tryptophan depletion, and on clinical trials that have been conducted using L-tryptophan supplementation. … changes in healthy adults, tryptophan depletion has …
2009967 citationsAnalysis, nutrition, and health benefits of tryptophan
M Friedman - International Journal of Tryptophan Research, 2018 - journals.sagepub.com
… For example, it has been reported that the dietary supplementation of tryptophan to healthy adults (n = 35) for the study period did not result in significant changes in serum cytokine …
2018398 citationsHarnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management
AC Chehadi, E Pereira de Lima… - International Journal of …, 2026 - mdpi.com
… and glial function, further linking gut health to brain plasticity and cognition [… supplementation [291,292]. By juxtaposing data from acute Trp depletion, non-plant derived supplementation…
20265 citationsNutritional importance of tryptophan for improving treatment in depression and diabetes
DJ Haleem - 2023 - academic.oup.com
… The importance of tryptophan supplementation for … for the optimal physiological and mental functions of our body, where bioactive metabolites of tryptophan help improve human health. …
202314 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-08-23. DSLD Label ID: 232279. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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