Optimized Folate®

Vitamins

Brand: Life Extension

Tablet or PillVitaminOff Market
Click to view full label

Net Contents

100 Vegetarian Tablet(s)

Serving Size

1 Vegetarian Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 37870 19391 3

Product Version

Q01939A

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

2Dietary Attributes

Label states: Vegetarian, Non-GMO.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Vegetarian Tablet(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Folate((6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)1000 mcg250%

Not Present

Other Ingredients

Microcrystalline CelluloseDicalcium PhosphateCroscarmellose SodiumSilicaVegetable StearateStearic Acid

Target Groups

VegetarianAdult (18 - 50 Years)

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: Children

WARNINGS: -Keep out of reach of children.

Precautions re: All Other

-DO NOT EXCEED RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Storage

Storage

Store tightly closed in a cool, dry place.

Formulation

Formula re: Contains

L-Methylfolate 1000 mcg

Formulation re: Does NOT Contain

Non-GMO

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Scan for product info

Brand IP Statement(s) re: (c), (TM), (SM)

^ Quatrefolic is a registered trademark of Gnosis, S.p.A., Patent number 7,947,662.

General: Product/Version Code

Q01939A

General Statements: All Other Content

Metabolically Active Form of Folic Acid

General Statements: All Other Content

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$3.00 – $2440.20· 40 listings
  • Life Extension High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets

    Life Extension4.8(2600)
    $13.50
  • Life Extension Optimized Folate, 1700 mcg DFE, 100 vegetarian tablets

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    $11.25
  • Life Extension Vegetarian Tablets

    Swanson Health Products4.8(2600)
    $11.25
  • Life Extension, Optimized Folate

    iHerb4.8(2600)
    $11.25
  • Life Extension 180 Vegetarian Tablets

    Walmart - Peak10 Health LLC4.8(6)
    $19.24
  • Life Extension BioActive Folate & Vitamin B12, 90 vegetarian capsules

    Life Extension4.8(3000)
    $9.00
  • Life Extension Optimized Folate

    Supplement First4.8(2600)
    $18.00
  • Life Extension High Potency Optimized Folate L-Methylfolate Vitamin | 8500 mcg Dfe | 30 Veg Tabs | Women's Health

    Swanson Health Products4.6(5)
    $13.50

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Mach Dich Wach! GmbH

    5.0 (33)

    Vitamin & supplements store

    Am Bocksberg 11, 63925 Laudenbach

Research & Studies

  • Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges

    H McNulty, M Ward, L Hoey, CF Hughes… - Proceedings of the …, 2019 - cambridge.org

    … As will be discussed later in this review, however, achieving optimal folate status for preventing NTD can be challenging for individuals and populations. Of note, rates of NTD in Ireland …

    2019111 citations
  • Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

    A Annibal, RG Tharyan, MF Schonewolff, H Tam… - Nature …, 2021 - nature.com

    … 1c and Supplementary Table 5). Given the biological importance of the folic acid pathway in human health … is causally linked to dhfr-1i life extension. Strikingly we saw similar changes in …

    2021115 citations
  • Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice

    HM Blank, SE Hammer, L Boatright… - Life Science …, 2024 - life-science-alliance.org

    … Limiting folate intake decreased … folate levels in mice with limited folic acid intake, these animals maintained their weight and adiposity late in life, and we did not observe adverse health …

    20245 citations
  • A role for supplements in optimizing health: the metabolic tune-up

    BN Ames - Archives of biochemistry and biophysics, 2004 - Elsevier

    An optimum intake of micronutrients and metabolites, which varies with age and genetic constitution, would tune up metabolism and give a marked increase in health, particularly for the …

    2004190 citations
  • Emerging roles for folate and related B-vitamins in brain health across the lifecycle

    C McGarel, K Pentieva, JJ Strain… - Proceedings of the …, 2015 - cambridge.org

    … Optimal folate status is essential throughout pregnancy for placental and fetal growth and … A pilot study (n 39), conducted by our group, examined the effect of folic acid supplementation …

    2015184 citations
  • Dietary Folate Regulates Organismal Growth and Longevity

    A Shahab - 2024 - search.proquest.com

    … the effect of endogenous folate produced by the gut microbes in impacting host health. In a … Certain life extension strategies and cancer treatments, such as Rapamycin targets and …

    2024

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2016-06-24. DSLD Label ID: 60600. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.