Optimized Folate 1000 mcg®

Vitamins

Brand: Life Extension

CapsuleVitaminOn Market

Functions

Women's Health

Product label for Optimized Folate 1000 mcg — Click to view full label

Net Contents

100 Vegetarian Capsule(s)

Serving Size

1 Vegetarian Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 37870 14391 8

Product Version

Q01439B

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Vegetarian Capsule(s) · 1 per day

Ingredient	Amount Per Serving	% Daily Value
Folate((6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)	1000 mcg	250%

Not Present

Other Ingredients

Microcrystalline CelluloseVegetable CelluloseSilicaVegetable Stearate

Target Groups

Adult (18 - 50 Years)

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Read the entire label and follow directions carefully prior to use. Directions: Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: Children

Warnings: - Keep out of reach of children.

Precautions re: All Other

- Do not exceed recommended dose. - Do not purchase if outer seal is broken or damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Storage

Store tightly closed in a cool, dry place.

Formulation

Formula re: Contains

L-Methylfolate Metabolically active form of Folic Acid

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Scan for product info

General: Product/Version Code

Q01439B

General Statements: All Other Content

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Brand IP Statement(s) re: (c), (TM), (SM)

Quatrefolic is a registered trademark of Gnosis S.p.A.

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

866-280-2852

info@lifeextension.com

Market Reference

$4.69 – $104.99· 35 listings

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Life Extension Optimized Folate
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$13.50
Life Extension, Optimized Folate
iHerb4.8(2600)
$11.25
Life Extension Optimized Folate, 1700 mcg DFE, 100 vegetarian tablets
Life Extension4.8(2600)
$11.25
Life Extension BioActive Folate & Vitamin B12, 90 vegetarian capsules
Life Extension4.8(3000)
$9.00
Life Extension BioActive Folate & Vitamin B12 150 Capsules
Walmart - Peak10 Health LLC5.0(11)
$14.75
Life Extension Prenatal Advantage Softgels
Life Extension4.8(1600)
$21.00
Life Extension BioActive Folate & Vitamin B12 90 Capsules
Herbs Direct4.8(3000)
$9.00

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Coalition Nutrition
4.9 (253)
Vitamin & supplements store
2026 E Old Lincoln Hwy, Langhorne, PA 19047
Directions (267) 560-2716
Nutrition Store: Going Out of Business Sale!
4.8 (170)
Vitamin & supplements store
1879 Street Rd, Bensalem, PA 19020
Directions (215) 638-7188
The Vitamin Shoppe
4.5 (108)
Vitamin & supplements store
620 Commerce Drive, Fairless Hills, PA 19030
Directions (215) 943-1848
Primal Nutrition
4.7 (75)
Vitamin & supplements store
8114 Roosevelt Blvd, Philadelphia, PA 19152
Directions (215) 613-5693
Optimal Nutrition
4.9 (70)
Vitamin & supplements store
801 County Line Rd, Horsham, PA 19044
Directions (267) 282-5313
GNC
4.3 (59)
Vitamin & supplements store
1298 E Lincoln Hwy Space 35, Levittown, PA 19056
Directions (215) 809-8005
Holly Hill Health Foods, Inc.
4.7 (160)
Vitamin & supplements store
1200 Welsh Rd Ste N, North Wales, PA 19454
Directions (215) 361-7770
The Vitamin Shoppe
4.6 (85)
Vitamin & supplements store
2601 Mt Holly Rd, Burlington, NJ 08016
Directions (609) 747-7888

Research & Studies

Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges
H McNulty, M Ward, L Hoey, CF Hughes… - Proceedings of the …, 2019 - cambridge.org
… cerns have arisen regarding potential adverse health effects of unmetabolised folic acid in the circulation arising through high folic acid exposures from supplements and fortified foods. …
2019111 citations
Is homocysteine making you sick? A new bioactive form of folic acid can lower stubbornly high homocysteine levels when ordinary B-vitamins fail
R Haas - Life Extension, 2009 - go.gale.com
… or 2,500 mcg folic acid, 50 mg vitamin B6, and 1,000 mcg … is far too high for optimal health. Studies indicate that people with … folic acid, the form of the vitamin used in most supplements …
2009
Nutrition throughout life: folate
H McNulty, K Pentieva, L Hoey, JJ Strain… - Int J Vitam Nutr …, 2012 - econtent.hogrefe.com
… for folate throughout the lifecycle, and some public health … of women who take folic acid supplements from before conception … The folic acid dose required to achieve optimal folate status …
201261 citations
The evolution of folate supplementation–from one size for all to personalized, precision, poly-paths
Q He, J Li - Journal of Translational Internal Medicine, 2023 - degruyterbrill.com
… The most used folate supplement is folic acid, a synthetic oxidative form, and folic acid grain fortification is a success story of public health. … This novel intervention aims to optimize folate …
202349 citations
Towards defining optimal concentrations of micronutrients in adults to optimize health
MDA Mahadzir, S Tan, S Elena, EM Chin… - Mechanisms of ageing …, 2025 - Elsevier
… to improve health outcomes and extend healthspan by defining optimal micronutrient concentrations. Future efforts should aim to establish evidence-based thresholds for optimal …
20258 citations
Folate: a key to optimizing health and reducing disease risk in the elderly
GC Rampersaud, GPA Kauwell… - Journal of the American …, 2003 - Taylor & Francis
… food folate and synthetic folic acid in supplements and … the health benefits associated with maintaining an optimal folate … adequate folate intake through increased consumption of folate-…
2003168 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2016-06-24. DSLD Label ID: 60812. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.