Melatonin 3 mg 6 Hour Timed Release

Non-Nutrient / Non-Botanical

Brand: Life Extension

Tablet or PillOn Market
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Net Contents

60 Vegetarian Tablet(s)

Serving Size

1 Vegetarian Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 37870 17866 8

Product Version

Not specified

Suggested Use

Read the entire label and follow the directions carefully prior to use.Directions: Take one (1) tablet 30 to 60 minutes before bedtime; or as recommended by a healthcare practitioner. Melatonin is naturally secreted from the pineal gland at night; and should be taken at night for optimal results.

Market Reference

$3.99 – $65.50· 24 listings
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Research & Studies

  • Melatonin: pharmacology, functions and therapeutic benefits

    S Tordjman, S Chokron, R Delorme… - Current …, 2017 - benthamdirect.com

    … ., 1 to 5 mg), allows within the hour after ingestion, melatonin … and health difficulties often show melatonin deficiency [51]. … clinical efficacy of melatonin supplementation in such disorders, …

    20171,191 citations
  • Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

    DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com

    … health prompted by the pandemic and its lasting effects on mental health and sleep disturbances, melatonin … For instance, 0.5 mg and 3.0 mg of melatonin taken eleven hours before the …

    2022215 citations
  • Rhythms of life: melatonin, nutrition, sleep, and antioxidant strategies for healthy aging

    CM Drăgoi, IB Dumitrescu, AC Nicolae - Frontiers in Neuroscience, 2026 - frontiersin.org

    … , including timed melatonin supplementation, dietary … physiological aging, and extending health span. Forthcoming research … calorie intake in daytime hours, avoiding large meals late in …

    2026
  • Melatonin pharmacokinetics following two different oral surge‐sustained release doses in older adults

    NS Gooneratne, AYZ Edwards, C Zhou… - Journal of pineal …, 2012 - Wiley Online Library

    … 0.3-mg controlled release melatonin were as follows: 1 hr, 0.1 mg; 3 hr, 0.3 mg; 5 hr, 0.3 mg; 7 hr, and 0.3 mg… to healthy subjects [48]. In patients with liver damage, the onset and peak of …

    2012149 citations
  • Melatonin: facts, extrapolations and clinical trials

    JA Boutin, DJ Kennaway, R Jockers - Biomolecules, 2023 - mdpi.com

    … suppliers of melatonin as a dietary supplement would ever … discovered in controlled experiments in healthy subjects; we … (from a few hours to a few days old) with quite desperate …

    202397 citations
  • A randomized, double-blind, crossover study to investigate the pharmacokinetics of extended-release melatonin compared to immediate-release melatonin in healthy …

    JG Mun, D Wang, DL Doerflein Fulk… - … Dietary Supplements, 2024 - Taylor & Francis

    … administration of this 4 mg extended-release formulation, melatonin levels fell below this … desirable time period with less risk of a next-day carryover effect. Thus, the rate of release is an …

    202422 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-08-23. DSLD Label ID: 232365. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.