High Potency Optimized Folate®

Vitamins

Brand: Life Extension

Tablet or PillVitaminOff Market

Product label for High Potency Optimized Folate — Click to view full label

Net Contents

30 Vegetarian Tablet(s)

Serving Size

1 Vegetarian Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 37870 19133 9

Product Version

Q01913A

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

1Dietary Attributes

Label states: Non-GMO.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Vegetarian Tablet(s) · 1 per day

Ingredient	Amount Per Serving	% Daily Value
Folate((6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)	5000 mcg	1250%

Not Present

Other Ingredients

Microcrystalline CelluloseDicalcium PhosphateStearic AcidCroscarmellose SodiumSilicaVegetable Stearate

Target Groups

Adult (18 - 50 Years)

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

CAUTION: Do not use this product if treated with methotrexate, fluorouracil, phenytoin, phenobarbital, primidone, or levodopa prior to consultation with your personal physician.

Precautions re: Children

WARNINGS: -Keep out of reach of children.

Precautions re: All Other

-DO NOT EXCEED RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

-When using nutritional supplements, please consult with you physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Storage

Store tightly closed in a cool, dry place.

Formulation

Formula re: Contains

High Potency Optimized Folate L-Methylfolate ~ 5000 mcg

Formula re: Contains

Metabolically Active Form of Folic Acid

Formulation re: Does NOT Contain

Non-GMO

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

Scan for product info

Brand IP Statement(s) re: (c), (TM), (SM)

Quatrefolic is a registered trademark of Gnosis, S.p.A., Patent number 7,947,662.

General: Product/Version Code

Q01913A

General Statements: All Other Content

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$3.00 – $83.00· 31 listings

Life Extension Optimized Folate
Natures Food Markets4.8(2600)
$13.69
Life Extension High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets
Life Extension4.8(2600)
$13.50
Life Extension, Optimized Folate
iHerb4.8(2600)
$11.25
Life Extension Optimized Folate, 1700 mcg DFE, 100 vegetarian tablets
Life Extension4.8(2600)
$11.25
Life Extension Vegetarian Tablets
Swanson Health Products4.8(2600)
$11.25
Life Extension 180 Vegetarian Tablets
Walmart - Peak10 Health LLC4.8(6)
$19.24
Life Extension BioActive Folate & Vitamin B12, 90 vegetarian capsules
Life Extension4.8(3000)
$9.00
Life Extension High Potency Optimized Folate L-Methylfolate Vitamin | 8500 mcg Dfe | 30 Veg Tabs | Women's Health
Swanson Health Products4.6(5)
$13.50

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

ITL Health
5.0 (37)
Vitamin & Supplements Shop
50 Broadway, London SW1H 0BL
Directions 0118 321 7628
Fitandfat
5.0 (321)
Vitamin & Supplements Shop
Inside the post office, 187 Uxbridge Rd, London W13 9AJ
Directions 020 8050 1277
Hashmats Health
4.7 (114)
Pharmaceutical company
123a, 125a The Broadway, Southall UB1 1LW
Directions 020 8574 7515
Healthshop UK
4.9 (41)
Health food shop
306 Grove Green Rd, London E11 4EA
Directions 07963 507732
Supplemented
4.7 (192)
Vitamin & Supplements Shop
Online Retail Ltd Box 1031A, Surbiton, Kingston upon Thames KT1 9AH
Directions
Love Life Supplements
4.8 (87)
Vitamin & Supplements Shop
wellington house, East Rd, Petersfield, Cambridge CB1 1BH
Directions 0800 122 3351
Dietapplements Limited
4.8 (6)
Vitamin & Supplements Shop
27 Old Gloucester St, London WC1N 3AX
Directions 01892 506990
London Supplements
3.7 (84)
Vitamin & Supplements Shop
13, Waverley Industrial Park Waverley Industrial Estate, Hailsham Dr, Harrow HA1 4TR
Directions 020 8863 0300

Research & Studies

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity
A Annibal, RG Tharyan, MF Schonewolff, H Tam… - Nature …, 2021 - nature.com
… Supplementary Table 5). Given the biological importance of the folic acid pathway in human health … major regulator of longevity whose mutation negates life extension in both daf-2 and …
2021115 citations
A role for supplements in optimizing health: the metabolic tune-up
BN Ames - Archives of biochemistry and biophysics, 2004 - Elsevier
An optimum intake of micronutrients and metabolites, which varies with age and genetic constitution, would tune up metabolism and give a marked increase in health, particularly for the …
2004190 citations
Addressing optimal folate and related B-vitamin status through the lifecycle: health impacts and challenges
H McNulty, M Ward, L Hoey, CF Hughes… - Proceedings of the …, 2019 - cambridge.org
… , however, achieving optimal folate status for preventing NTD can be challenging for individuals and populations. Of note, rates of NTD in Ireland are among the highest in the world. A …
2019111 citations
Dietary Folate Regulates Organismal Growth and Longevity
A Shahab - 2024 - search.proquest.com
… the effect of endogenous folate produced by the gut microbes in impacting host health. In a … Certain life extension strategies and cancer treatments, such as Rapamycin targets and …
2024
Emerging roles for folate and related B-vitamins in brain health across the lifecycle
C McGarel, K Pentieva, JJ Strain… - Proceedings of the …, 2015 - cambridge.org
… Folate, an important cofactor in C1 metabolism, is indirectly … role for folate and the related B-vitamins in brain health across the … Optimal folate status is essential throughout pregnancy for …
2015184 citations
Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans
L Rathor, BA Akhoon, S Pandey, S Srivastava… - Age, 2015 - Springer
… Long life and healthy aging depend on dynamic interactions among biological, psychological, and environmental factors. Aging is a major risk factor for various diseases, such as …
201564 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2016-05-22. DSLD Label ID: 59599. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.