Endothelial Defense Pomegranate Plus®

Other Combinations

Brand: Life Extension

Softgel CapsuleOther CombinationsOn Market
Click to view full label

Net Contents

60 Softgel(s)

Serving Size

2 Softgel(s)

Servings Per Container

30

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 37870 24976 4

Product Version

L02497C

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

9Active Ingredients

9 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

2% Daily Value Coverage

2 ingredients report an established %DV per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Softgel(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Calories20 Calorie(s)
Total Fat1.5 Gram(s)2%
Total Carbohydrates1 Gram(s)1%
Protein< 1 Gram(s)
Cardiose Flavonoid Glycoside(Immature Sweet Orange, Rutinoside)500 mg
Pomella(Pomegranate Fruit Extract)400 mg
Proprietary Pomegranate Blend(Pomegranate flower extract, Pomegranate seed Oil, Punicic Acid)137.5 mg
Pomegranate Fruit Extract100 mg
Extramel(Melon Fruit Pulp Concentrate)36 mg
Superoxide Dismutase500 IU

% Daily Values are based on a 2,000 Calorie Diet.

Other Ingredients

Extra Virgin Olive OilGelatinGlycerinSunflower LecithinWater, PurifiedBeeswaxCarobDextrin

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: All Other

Read the entire label and follow the directions carefully.

Precautions re: Children

Warnings: Keep out of reach of children.

Precautions re: All Other

Do not exceed recommended dose. Do not purchase if outer seal is damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Precautions re: All Other

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Storage

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Gluten Free Non GMO Le Certified

Formulation re: Other

Comprehensive arterial support

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Scan for product info

Brand IP Statement(s) re: (c), (TM), (SM)

Cardiose is a registered trademark of HealthTech Bio Actives S.L. POMELLA Extract is covered under U.S. Patent 7,638,640 and POMELLA is a registered trademark of Verdure Sciences, Inc. Extramel is a registered trademark of Bionov.

Seals/Symbols

Non GMO Le Certified

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$16.00 – $4263.60· 11 listings
  • Life Extension Pomegranate Fruit Extract 30 Capsules

    Fruitful Yield4.7(493)
    $16.00Lowest
  • Life Extension Pomegranate Complete Softgels

    Life Extension4.7(520)
    $18.00
  • Life Extension Blueberry Extract and Pomegranate 60 Capsules

    Life Extension4.8(478)
    $22.50
  • Life Extension endothelial Defense Pomegranate Plus Softgels

    GoSupps.com4.8(46)
    $79.99
  • Pomegranate Plus Pure Encapsulations

    Pure Prescriptions4.7(17)
    $72.50
  • Pomegranate Plus

    RTHM4.7(17)
    $4263.60
  • Life Extension Endothelial Defense Full-Spectrum Pomegranate and Cordiart Softgels

    Markowa Apteka Pharmacy4.6(30)
    $56.00
  • Life Extension Full-Spectrum Pomegranate Softgels

    TheNatural.com4.7(520)
    $18.00

Where to Buy Locally

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Research & Studies

  • Enhance endothelial health

    J Harrison - Life Extension, 2014 - go.gale.com

    … Pomegranate extracts act via several different, but complementary mechanisms to restore the body's endothelial defenses, lowering … Pomegranate extracts have been shown to promote …

    2014
  • Protective effects of pomegranate in endothelial dysfunction

    NTB Delgado, WN Rouver… - Current Pharmaceutical …, 2020 - benthamdirect.com

    … role of pomegranate in the context of endothelial dysfunction … endothelial cells, a 20-minute exposure to pomegranate … in 83 %, while the consumption of pomegranate juice was found to …

    202023 citations
  • Effects of pomegranate peel extract and vitamin E on the inflammatory status and endothelial function in hemodialysis patients: a randomized controlled clinical trial

    T Jafari, AA Fallah, A Reyhanian, E Sarmast - Food & function, 2020 - pubs.rsc.org

    … on inflammation and endothelial … used pomegranate juice, extract, or oil in healthy, hypertensive, dyslipidemic, or diabetic subjects. They reported that pomegranate supplementation …

    202026 citations
  • Effects of Pomegranate on Vascular Endothelial Function: A Systematic Review and Meta-Analysis of Clinical Trials

    A Kazemi, N Deylami, S Shojaei-Zarghani… - … Dietary Supplements, 2025 - Taylor & Francis

    … The results of the present meta-analysis demonstrated the beneficial effects of pomegranate on certain markers of vascular endothelial function, including ICAM-1 and IL-6, but no effect …

    20253 citations
  • Preclinical evaluation of waste-derived pomegranate extract (PWE) as a potential preventing and therapeutic agent for benign prostatic hyperplasia

    V Consoli, AG D'Amico, C Russo, E Foderà… - Frontiers in Molecular …, 2026 - frontiersin.org

    … administered with pomegranate extract (… pomegranate extract (PWE; Medgranate™, Medinutrex, Catania, Italy) used in this study was derived from “Wonderful” variety pomegranate by-…

    2026
  • Vascular action of polyphenols

    D Ghosh, A Scheepens - Molecular nutrition & food research, 2009 - Wiley Online Library

    … There is abundant mythological and historical evidence regarding the health benefits of pomegranate fruit [75]. The fruit of the pomegranate (L50% of total pomegranate weight) consists …

    2009290 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-04-24. DSLD Label ID: 328442. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.