Endothelial Defense Pomegranate Plus®
Other CombinationsBrand: Life Extension
Functions
Net Contents
60 Softgel(s)
Serving Size
2 Softgel(s)
Servings Per Container
30
Supplement Form
Softgel Capsule
Bar Code (UPC/SKU)
7 37870 24976 4
Product Version
L02497C
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
9 distinct active ingredients are disclosed in Supplement Facts.
Label includes a proprietary blend, so some individual amounts are not itemized.
2 ingredients report an established %DV per serving.
Label states: Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Softgel(s) · 1 per day
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Calories | 20 Calorie(s) | — |
| Total Fat | 1.5 Gram(s) | 2% |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Protein | < 1 Gram(s) | — |
| Cardiose Flavonoid Glycoside(Immature Sweet Orange, Rutinoside) | 500 mg | — |
| Pomella(Pomegranate Fruit Extract) | 400 mg | — |
| Proprietary Pomegranate Blend(Pomegranate flower extract, Pomegranate seed Oil, Punicic Acid) | 137.5 mg | — |
| Pomegranate Fruit Extract | 100 mg | — |
| Extramel(Melon Fruit Pulp Concentrate) | 36 mg | — |
| Superoxide Dismutase | 500 IU | — |
% Daily Values are based on a 2,000 Calorie Diet.
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.
Warnings & Precautions
Precautions re: All Other
Read the entire label and follow the directions carefully.
Precautions re: Children
Warnings: Keep out of reach of children.
Precautions re: All Other
Do not exceed recommended dose. Do not purchase if outer seal is damaged.
Precautions re: Pregnant or Nursing or Prescription Medications
Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Precautions re: All Other
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Storage
Storage
Store tightly closed in a cool, dry place.
Formulation
Formulation re: Does NOT Contain
Gluten Free Non GMO Le Certified
Formulation re: Other
Comprehensive arterial support
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
Scan for product info
Brand IP Statement(s) re: (c), (TM), (SM)
Cardiose is a registered trademark of HealthTech Bio Actives S.L. POMELLA Extract is covered under U.S. Patent 7,638,640 and POMELLA is a registered trademark of Verdure Sciences, Inc. Extramel is a registered trademark of Bionov.
Seals/Symbols
Non GMO Le Certified
Manufacturer & Distributor
Distributor
Quality Supplements and Vitamins, Inc.
Ft. Lauderdale, FL, 33309
1-866-280-2852
Market Reference
Life Extension Pomegranate Fruit Extract 30 Capsules
Fruitful Yield4.7(493)$16.00LowestLife Extension Pomegranate Complete Softgels
Life Extension4.7(520)$18.00Life Extension Blueberry Extract and Pomegranate 60 Capsules
Life Extension4.8(478)$22.50Life Extension endothelial Defense Pomegranate Plus Softgels
GoSupps.com4.8(46)$79.99Pomegranate Plus Pure Encapsulations
Pure Prescriptions4.7(17)$72.50Pomegranate Plus
RTHM4.7(17)$4263.60Life Extension Endothelial Defense Full-Spectrum Pomegranate and Cordiart Softgels
Markowa Apteka Pharmacy4.6(30)$56.00Life Extension Full-Spectrum Pomegranate Softgels
TheNatural.com4.7(520)$18.00
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.3 (183)Vitamin & supplements store
12 4th Ave, Brooklyn, NY 11217
GNC
4.0 (225)Vitamin & supplements store
134-136 Fulton St, New York, NY 10038
GNC
4.4 (88)Vitamin & supplements store
753 Broadway Spc 753, New York, NY 10003
Pure Essentials Supplements
5.0 (1)Vitamin & supplements store
121 Varick St, New York, NY 10013
The Vitamin Shoppe
3.9 (84)Vitamin & supplements store
32 Court St, Brooklyn, NY 11201
GNC
4.7 (197)Vitamin & supplements store
2 Pennsylvania Plaza Ste 29B, New York, NY 10121
The Vitamin Shoppe
4.4 (98)Vitamin & supplements store
257 8th Ave, New York, NY 10011
The Vitamin Shoppe
4.3 (163)Vitamin & supplements store
385 5th Ave, New York, NY 10016
Research & Studies
Enhance endothelial health
J Harrison - Life Extension, 2014 - go.gale.com
… Pomegranate extracts act via several different, but complementary mechanisms to restore the body's endothelial defenses, lowering … Pomegranate extracts have been shown to promote …
2014Protective effects of pomegranate in endothelial dysfunction
NTB Delgado, WN Rouver… - Current Pharmaceutical …, 2020 - benthamdirect.com
… role of pomegranate in the context of endothelial dysfunction … endothelial cells, a 20-minute exposure to pomegranate … in 83 %, while the consumption of pomegranate juice was found to …
202023 citationsEffects of pomegranate peel extract and vitamin E on the inflammatory status and endothelial function in hemodialysis patients: a randomized controlled clinical trial
T Jafari, AA Fallah, A Reyhanian, E Sarmast - Food & function, 2020 - pubs.rsc.org
… on inflammation and endothelial … used pomegranate juice, extract, or oil in healthy, hypertensive, dyslipidemic, or diabetic subjects. They reported that pomegranate supplementation …
202026 citationsEffects of Pomegranate on Vascular Endothelial Function: A Systematic Review and Meta-Analysis of Clinical Trials
A Kazemi, N Deylami, S Shojaei-Zarghani… - … Dietary Supplements, 2025 - Taylor & Francis
… The results of the present meta-analysis demonstrated the beneficial effects of pomegranate on certain markers of vascular endothelial function, including ICAM-1 and IL-6, but no effect …
20253 citationsPreclinical evaluation of waste-derived pomegranate extract (PWE) as a potential preventing and therapeutic agent for benign prostatic hyperplasia
V Consoli, AG D'Amico, C Russo, E Foderà… - Frontiers in Molecular …, 2026 - frontiersin.org
… administered with pomegranate extract (… pomegranate extract (PWE; Medgranate™, Medinutrex, Catania, Italy) used in this study was derived from “Wonderful” variety pomegranate by-…
2026Vascular action of polyphenols
D Ghosh, A Scheepens - Molecular nutrition & food research, 2009 - Wiley Online Library
… There is abundant mythological and historical evidence regarding the health benefits of pomegranate fruit [75]. The fruit of the pomegranate (L50% of total pomegranate weight) consists …
2009290 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-04-24. DSLD Label ID: 328442. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
Related Products

01-02 Enhanced Fat Melting Matrix
ATS Labs

1000 mg Vitamin C Acai Berry
Emergen-C

1000 mg Vitamin C Cranberry Pomegranate
Emergen-C

1000 MG Vitamin C Cranberry-Pomegranate
Emergen-C