Endothelial Defense Pomegranate Plus®

Other Combinations

Brand: Life Extension

Softgel CapsuleOther CombinationsOn Market
Click to view full label

Net Contents

60 Softgel(s)

Serving Size

2 Softgel(s)

Servings Per Container

30

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 37870 24976 4

Product Version

L02497C

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

9Active Ingredients

9 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

2% Daily Value Coverage

2 ingredients report an established %DV per serving.

2Dietary Attributes

Label states: Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 2 Softgel(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Calories20 Calorie(s)
Total Fat1.5 Gram(s)2%
Total Carbohydrates1 Gram(s)1%
Protein< 1 Gram(s)
Cardiose Flavonoid Glycoside(Immature Sweet Orange, Rutinoside)500 mg
Pomella(Pomegranate Fruit Extract)400 mg
Proprietary Pomegranate Blend(Pomegranate flower extract, Pomegranate seed Oil, Punicic Acid)137.5 mg
Pomegranate Fruit Extract100 mg
Extramel(Melon Fruit Pulp Concentrate)36 mg
Superoxide Dismutase500 IU

% Daily Values are based on a 2,000 Calorie Diet.

Other Ingredients

Extra Virgin Olive OilGelatinGlycerinSunflower LecithinWater, PurifiedBeeswaxCarobDextrin

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: All Other

Read the entire label and follow the directions carefully.

Precautions re: Children

Warnings: Keep out of reach of children.

Precautions re: All Other

Do not exceed recommended dose. Do not purchase if outer seal is damaged.

Precautions re: Pregnant or Nursing or Prescription Medications

Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Precautions re: All Other

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Storage

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Gluten Free Non GMO Le Certified

Formulation re: Other

Comprehensive arterial support

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Scan for product info

Brand IP Statement(s) re: (c), (TM), (SM)

Cardiose is a registered trademark of HealthTech Bio Actives S.L. POMELLA Extract is covered under U.S. Patent 7,638,640 and POMELLA is a registered trademark of Verdure Sciences, Inc. Extramel is a registered trademark of Bionov.

Seals/Symbols

Non GMO Le Certified

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$13.50 – $85.50· 16 listings
  • Life Extension Endothelial Defense Full-Spectrum Pomegranate and Cordiart Softgels

    Markowa Apteka Pharmacy4.6(30)
    $56.00
  • Life Extension endothelial Defense Pomegranate Plus Softgels

    GoSupps.com4.8(45)
    $74.99
  • Life Extension Endothelial Defense Pomegranate Complete 60 Softgels

    Pure Prescriptions4.8(6)
    $24.00
  • Life Extension Pomegranate Fruit Extract 30 Capsules

    Walmart - Life Extension Buyers Club4.7(508)
    $13.50Lowest
  • Life Extension Pomegranate Complete Softgels

    Walmart - Life Extension Buyers Club4.7(531)
    $18.00
  • THREE PACK SALE Life Extension Pomegranate Fruit Extract 30 cap

    eBay4.7(508)
    $40.00
  • FOUR PACK Life Extension Pomegranate Complete 30 gels TAKE OFF $8

    eBay4.7(531)
    $64.00
  • Pomegranate Plus Pure Encapsulations

    Target4.7(18)
    $72.50

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • Supplement Superstore

    5.0 (1144)

    Vitamin & supplements store

    14004 Manchester Rd #4514, Ballwin, MO 63011

  • The Vitamin Shoppe

    4.2 (136)

    Vitamin & supplements store

    2705 N Elston Ave, Chicago, IL 60647

  • PureFormulas

    4.7 (1089)

    Vitamin & supplements store

    11800 NW 102nd Rd #2, Medley, FL 33178

  • e-NutritionStore.com

    5.0 (10)

    Vitamin & supplements store

    6010 Meadowridge Center Dr K, Elkridge, MD 21075

  • Supplement Superstore

    5.0 (1389)

    Vitamin & supplements store

    8420 Eager Rd, St. Louis, MO 63144

  • SameDaySupplements.com

    4.5 (503)

    Vitamin & supplements store

    64 Nancy St Unit c, West Babylon, NY 11704

  • The Vitamin Shoppe

    4.5 (63)

    Vitamin & supplements store

    191 Walt Whitman Rd #110, Huntington Station, NY 11746

  • Supplement Superstore

    5.0 (734)

    Vitamin & supplements store

    2090 Washington Crossing, Washington, MO 63090

Research & Studies

  • Enhance endothelial health

    J Harrison - Life Extension, 2014 - go.gale.com

    … Pomegranate extracts act via several different, but complementary mechanisms to restore the body's endothelial defenses, lowering … Pomegranate extracts have been shown to promote …

    2014
  • Protective effects of pomegranate in endothelial dysfunction

    NTB Delgado, WN Rouver… - Current Pharmaceutical …, 2020 - benthamdirect.com

    … role of pomegranate in the context of endothelial dysfunction … endothelial cells, a 20-minute exposure to pomegranate … in 83 %, while the consumption of pomegranate juice was found to …

    202023 citations
  • Phytonutrients in the promotion of healthspan: a new perspective

    EF Jacquier, A Kassis, D Marcu, N Contractor… - Frontiers in …, 2024 - frontiersin.org

    … pomegranate have also highlighted potential health benefits. For instance, the consumption of raspberry juice was associated with improved endothelial … ) and pomegranate extract in …

    202414 citations
  • Effects of Pomegranate on Vascular Endothelial Function: A Systematic Review and Meta-Analysis of Clinical Trials

    A Kazemi, N Deylami, S Shojaei-Zarghani… - … Dietary Supplements, 2025 - Taylor & Francis

    … The results of the present meta-analysis demonstrated the beneficial effects of pomegranate on certain markers of vascular endothelial function, including ICAM-1 and IL-6, but no effect …

    20253 citations
  • Protective Role of Polyphenols against Vascular Inflammation, Aging and Cardiovascular Disease.

    A Serino, G Salazar - Nutrients, 2019 - search.ebscohost.com

    … The protective effect of tea polyphenols in cardiovascular health was recently reviewed by others [120,121]. Detailed information on the role of catechins in oxidative stress defense …

    2019304 citations
  • Fueling immunity: the synergy of natural products and exercise for optimal health

    F Li, W Zhou, J Wang - Frontiers in Pharmacology, 2025 - frontiersin.org

    … However, the role of pomegranate supplementation in reducing oxidative stress is even more promising. In a randomized clinical trial on postmenopausal women with T2D (…

    20256 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-04-24. DSLD Label ID: 328442. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.