Endothelial Defense Pomegranate Plus®

Other Combinations

Brand: Life Extension

Softgel CapsuleOther CombinationsOn Market

Functions

Heart & Circulation

Product label for Endothelial Defense Pomegranate Plus — Click to view full label

Net Contents

60 Softgel(s)

Serving Size

2 Softgel(s)

Servings Per Container

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 37870 24976 4

Product Version

L02497A

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

9Active Ingredients

9 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

2% Daily Value Coverage

2 ingredients report an established %DV per serving.

1Dietary Attributes

Label states: Non-GMO.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 2 Softgel(s) · 1 per day

Ingredient	Amount Per Serving	% Daily Value
Calories	20 Calorie(s)	—
Total Fat	1.5 Gram(s)	2%
Total Carbohydrates	1 Gram(s)	1%
Protein	< 1 Gram(s)	—
Cardiose Flavonoid Glycoside(Immature Sweet Orange, Rutinoside)	500 mg	—
Pomella Pomegranate extract(Punicalagins)	400 mg	—
Proprietary Pomegranate Blend(Pomegranate flower extract, Pomegranate seed Oil, Punicic Acid)	137.5 mg	—
Pomegranate 5:1 extract	100 mg	—
Extramel Melon pulp concentrate(Superoxide Dismutase)	36 mg	—

% Daily Values are based on a 2,000 calorie diet

Other Ingredients

extra virgin Olive OilGelatinGlycerinSunflower Lecithinpurified WaterBeeswaxCarob colorDextrin

Target Groups

Adult (18 - 50 Years)

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. Directions: Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.

Warnings & Precautions

Precautions re: Children

Warnings: Keep out of reach of children.

Precautions re: All Other

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

Precautions re: Children

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Precautions re: All Other

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Storage

Store tightly closed in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

Non GMO LE Certified

Formulation re: Other

Comprehensive arterial support

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Brand IP Statement(s) re: (c), (TM), (SM)

Cardiose is a registered trademark of INTERQUIM, S.A. d.b.a. Ferrer HealthTech. POMELLA Extract is covered under U.S. Patent 7,638,640 and POMELLA is a registered trademark of Verdure Sciences, Inc. Extramel is a registered trademark of Bionov.

Seals/Symbols

Non GMO LE Certified

Manufacturer & Distributor

Distributor

Quality Supplements and Vitamins, Inc.

Ft. Lauderdale, FL, 33309

1-866-280-2852

Market Reference

$13.50 – $89.99· 10 listings

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Markowa Apteka Pharmacy4.6(30)
$56.00
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Pure Prescriptions4.8(6)
$24.00
Life Extension Pomegranate Fruit Extract 30 Capsules
Walmart - Life Extension Buyers Club4.7(508)
$13.50Lowest
Life Extension endothelial Defense Pomegranate Plus Softgels
GoSupps.com4.8(45)
$74.99
Life Extension Pomegranate Complete Softgels
Life Extension4.7(531)
$18.00
Life Extension Blueberry Extract and Pomegranate 60 Capsules
Life Extension4.8(483)
$22.50
Pomegranate Plus Pure Encapsulations
Pure Prescriptions4.7(18)
$72.50
Life Extension Full-Spectrum Pomegranate Softgels
TheNatural.com4.9(8)
$18.00

Where to Buy Locally

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CelXpert
5.0 (67)
Vitamin & supplements store
Jan Campertstraat 5, 6416 SG Heerlen
Directions 045 404 2739
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Directions 045 700 9702
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4.4 (99)
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Directions 020 888 5031
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Sint Barbarastraat 92, 6415 RX Heerlen
Directions 06 41780515
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5.0 (8)
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Van Gronsveldstraat 9, 6463 CA Kerkrade
Directions +49 1573 3300100
Vitamintrend B.V.
2.6 (8)
Vitamin & supplements store
Economiestraat 39, 6433 KC Hoensbroek
Directions 045 523 4840
Erica Kruiderijen Heerlen
4.6 (48)
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Geleenstraat 64, 6411 HT Heerlen
Directions 045 571 3024

Research & Studies

Enhance endothelial health
J Harrison - Life Extension, 2014 - go.gale.com
… Pomegranate extracts act via several different, but complementary mechanisms to restore the body's endothelial defenses, lowering … Pomegranate extracts have been shown to promote …
2014
Protective effects of pomegranate in endothelial dysfunction
NTB Delgado, WN Rouver… - Current Pharmaceutical …, 2020 - benthamdirect.com
… role of pomegranate in the context of endothelial dysfunction … endothelial cells, a 20-minute exposure to pomegranate … in 83 %, while the consumption of pomegranate juice was found to …
202023 citations
Phytonutrients in the promotion of healthspan: a new perspective
EF Jacquier, A Kassis, D Marcu, N Contractor… - Frontiers in …, 2024 - frontiersin.org
… pomegranate have also highlighted potential health benefits. For instance, the consumption of raspberry juice was associated with improved endothelial … ) and pomegranate extract in …
202414 citations
Effects of Pomegranate on Vascular Endothelial Function: A Systematic Review and Meta-Analysis of Clinical Trials
A Kazemi, N Deylami, S Shojaei-Zarghani… - … Dietary Supplements, 2025 - Taylor & Francis
… The results of the present meta-analysis demonstrated the beneficial effects of pomegranate on certain markers of vascular endothelial function, including ICAM-1 and IL-6, but no effect …
20253 citations
Protective Role of Polyphenols against Vascular Inflammation, Aging and Cardiovascular Disease.
A Serino, G Salazar - Nutrients, 2019 - search.ebscohost.com
… The protective effect of tea polyphenols in cardiovascular health was recently reviewed by others [120,121]. Detailed information on the role of catechins in oxidative stress defense …
2019304 citations
Fueling immunity: the synergy of natural products and exercise for optimal health
F Li, W Zhou, J Wang - Frontiers in Pharmacology, 2025 - frontiersin.org
… However, the role of pomegranate supplementation in reducing oxidative stress is even more promising. In a randomized clinical trial on postmenopausal women with T2D (…
20256 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2020-08-23. DSLD Label ID: 232748. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.