Brand: Karuna

CapsuleOn Market
Click to view full label

Net Contents

120 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 18647 08109 2

Product Version

Not specified

Suggested Use

Suggested use for adults:1-4 capsules per day in divided doses with meals; or as directed by your health care practitioner.

Market Reference

$4.15 – $565.50· 40 listings
  • Karuna Pregnenolone 50 mg 120 Capsules

    Supplement First5.0(7)
    $43.20
  • Karuna Progesterone Pure

    Avalon Professional Pharmacy
    $53.99
  • Karuna Progesterone Plus Cream

    Blue Sky Vitamin4.9(9)
    $54.60
  • BulkSupplements Pregnenolone Capsules

    Target4.6(11)
    $17.97
  • Horbaach Pregnenolone 100mg 180 Capsules

    Walmart - Carlyle Nutritionals, LLC5.0(5)
    $16.99
  • Pure Encapsulations Pregnenolone mg

    Pure Prescriptions4.8(158)
    $14.50
  • Pregnenolone 25 mg 60 Tablets

    Life Extension4.3(25)
    $31.50
  • Pregnenolone Cream 4 oz.

    Supplement Spot4.7(7)
    $34.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Research & Studies

  • Pregnenolone 50mg Micronized Lipid Matrix

    WI Does, HI Works - fullscript.com

    … Pregnenolone is a neurosteroid and hormone precursor that plays a vital role in the production of … Pregnenolone helps bridge the gap between hormone synthesis and brain health, …

  • Pregnenolone & Its Metabolites: Central Nervous System Effects.

    C DECKER - Naturopathic Doctor News & Review, 2021 - search.ebscohost.com

    … Pregnenolone and its derivatives may … pregnenolone (PREG), while estrogen and As compared with … In and ALLO-P each have been shown to have health with aging: when taken at a …

    2021
  • Over-the-counter “adrenal support” supplements contain thyroid and steroid-based adrenal hormones

    HK Akturk, AM Chindris, JM Hines, RJ Singh… - Mayo Clinic …, 2018 - Elsevier

    … In this study, 90% of dietary supplements marketed for thyroid health … Health and Safety Code, Section 110423(b) prohibits the sale of dietary supplements containing pregnenolone, …

    201823 citations
  • Neurosteroid Levels in Pregnancy and Its Implications for Mental Health: A Literature Review

    K Gokulakrishnan, V Mohan… - Annals of …, 2025 - journals.sagepub.com

    … tissues were rich in steroids such as pregnenolone (Preg) and … Mental health disorders such as depression and anxiety … Further, it could affect the mental health of the mother during …

    2025
  • GABAergic neuroactive steroid response to sertraline in premenstrual dysphoric disorder

    KN Miller, L Standeven, AL Morrow, JL Payne… - …, 2024 - Elsevier

    Rationale Premenstrual dysphoric disorder (PMDD) affects approximately 5% of menstruating individuals, with significant negative mood symptoms in the luteal phase of the menstrual …

    202424 citations
  • Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23

    Y Ma, K Sachdeva, J Liu, M Ford, D Yang… - Drug metabolism and …, 2004 - Elsevier

    … In addition, treatment with dihydromethysticin, desmethoxyyangonin, or pregnenolone 16α-carbonitrile (PCN) markedly increased the levels of CYP3A23 mRNA, and inhibition of mRNA …

    200444 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-07-25. DSLD Label ID: 35805. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.