Brand: Karuna

CapsuleNon-Nutrient/Non-BotanicalOn Market
Click to view full label

Net Contents

120 Capsule(s)

Serving Size

1–4 Capsule(s)

Servings Per Container

120

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 18647 08109 2

Product Version

8109-LB6

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Wheat
  • Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1–4 Capsule(s) · 1 per day

IngredientAmount Per Serving
Pregnenolone50 mg—

Not Present

Other Ingredients

Rice Flour

Target Groups

Adult (18 - 50 Years)Dairy FreeSugar Free

Label Claims

All Other

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested use for adults: 1-4 capsules per day in divided doses with meals, or as directed by your health care practitioner.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Precautions re: Children

Caution: Not for use by individuals under the age of 18 years.

Precautions re: Children

Keep out of reach of children.

Storage

Storage

Keep in a cool, dry place, tightly capped.

Formulation

Formulation re: Does NOT Contain

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

FDA Statements

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General Statements: All Other Content

Steroid Hormone Precursor

Seals/Symbols

KARUNA(R) RESPONSIBLE NUTRITION(TM)

General Statements: All Other Content

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

General: Product/Version Code

8109-LB6

Manufacturer & Distributor

Manufacturer

Karuna Corporation

42 Digital Drive #7, Novato, CA, 94949

Market Reference

$4.15 – $565.50· 40 listings
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Where to Buy Locally

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Research & Studies

  • Pregnenolone 50mg Micronized Lipid Matrix

    WI Does, HI Works - fullscript.com

    … Pregnenolone is a neurosteroid and hormone precursor that plays a vital role in the production of … Pregnenolone helps bridge the gap between hormone synthesis and brain health, …

  • Pregnenolone & Its Metabolites: Central Nervous System Effects.

    C DECKER - Naturopathic Doctor News & Review, 2021 - search.ebscohost.com

    … Pregnenolone and its derivatives may … pregnenolone (PREG), while estrogen and As compared with … In and ALLO-P each have been shown to have health with aging: when taken at a …

    2021
  • Over-the-counter “adrenal support” supplements contain thyroid and steroid-based adrenal hormones

    HK Akturk, AM Chindris, JM Hines, RJ Singh… - Mayo Clinic …, 2018 - Elsevier

    … In this study, 90% of dietary supplements marketed for thyroid health … Health and Safety Code, Section 110423(b) prohibits the sale of dietary supplements containing pregnenolone, …

    201823 citations
  • Neurosteroid Levels in Pregnancy and Its Implications for Mental Health: A Literature Review

    K Gokulakrishnan, V Mohan… - Annals of …, 2025 - journals.sagepub.com

    … tissues were rich in steroids such as pregnenolone (Preg) and … Mental health disorders such as depression and anxiety … Further, it could affect the mental health of the mother during …

    2025
  • GABAergic neuroactive steroid response to sertraline in premenstrual dysphoric disorder

    KN Miller, L Standeven, AL Morrow, JL Payne… - …, 2024 - Elsevier

    Rationale Premenstrual dysphoric disorder (PMDD) affects approximately 5% of menstruating individuals, with significant negative mood symptoms in the luteal phase of the menstrual …

    202424 citations
  • Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23

    Y Ma, K Sachdeva, J Liu, M Ford, D Yang… - Drug metabolism and …, 2004 - Elsevier

    … In addition, treatment with dihydromethysticin, desmethoxyyangonin, or pregnenolone 16α-carbonitrile (PCN) markedly increased the levels of CYP3A23 mRNA, and inhibition of mRNA …

    200444 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2014-07-25. DSLD Label ID: 35805. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.