Net Contents
120 Capsule(s)
Serving Size
1–4 Capsule(s)
Servings Per Container
120
Supplement Form
Capsule
Bar Code (UPC/SKU)
0 18647 08109 2
Product Version
8109-LB5
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Wheat
- Soy
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1–4 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| Pregnenolone | 50 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested use for adults: 1-4 capsules per day in divided doses with meals, or as directed by your health care practitioner.
Warnings & Precautions
Precautions re: Children
Caution: Not for use by individuals under the age of 18 years.
Precautions re: Children
Keep out of reach of children.
Precautions re: Pregnant or Nursing or Prescription Medications
Do not use if pregnant or nursing.
Storage
Storage
Keep in a cool, dry place, tightly capped.
Formulation
Formulation re: Does NOT Contain
This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.
FDA Statements
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
KARUNA(R) RESPONSIBLE NUTRITION(TM)
General Statements: All Other Content
Steroid Hormone Precursor
General Statements: All Other Content
This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.
General: Product/Version Code
8109-LB5
Manufacturer & Distributor
Manufacturer
Karuna Corporation
42 Digital Drive #7, Novato, CA, 94949
Market Reference
Karuna Pregnenolone 50 mg 120 Capsules
Supplement First5.0(7)$43.20Karuna Progesterone Pure
Avalon Professional Pharmacy$53.99Karuna Progesterone Plus Cream
Blue Sky Vitamin4.9(9)$54.60Horbaach Pregnenolone 100mg 180 Capsules
Target5.0(5)$17.99Pure Encapsulations Pregnenolone mg
Pure Prescriptions4.8(158)$14.50Nootropics Depot Pregnenolone Tablets Quick Dissolve Micronized 365ct. 5mg
Nootropics Depot4.6(12)$39.99BulkSupplements Pregnenolone Capsules
Target4.6(11)$17.97Pregnenolone 25 mg 60 Tablets
Life Extension4.3(25)$31.50
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Nutrabalance
5.0 (1)Vitamin & supplements store
1123 E West Maple Rd Ste 7, Walled Lake, MI 48390
The Vitamin Shoppe
4.6 (103)Vitamin & supplements store
30730 Orchard Lake Rd, Farmington Hills, MI 48334
The Vitamin Shoppe
4.7 (63)Vitamin & supplements store
8533 W Grand River Ave, Brighton, MI 48116
The Vitamin Shoppe
4.6 (112)Vitamin & supplements store
3970 Baldwin Rd, Auburn Hills, MI 48326
The Vitamin Shoppe
4.4 (86)Vitamin & supplements store
20580 Haggerty Rd, Northville, MI 48167
The Vitamin Shoppe
4.5 (178)Vitamin & supplements store
12687 Middlebelt Rd, Livonia, MI 48150
Research & Studies
Pregnenolone 50mg Micronized Lipid Matrix
WI Does, HI Works - fullscript.com
… Pregnenolone is a neurosteroid and hormone precursor that plays a vital role in the production of … Pregnenolone helps bridge the gap between hormone synthesis and brain health, …
GABAergic neuroactive steroid response to sertraline in premenstrual dysphoric disorder
KN Miller, L Standeven, AL Morrow, JL Payne… - …, 2024 - Elsevier
Rationale Premenstrual dysphoric disorder (PMDD) affects approximately 5% of menstruating individuals, with significant negative mood symptoms in the luteal phase of the menstrual …
202424 citationsDesmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23
Y Ma, K Sachdeva, J Liu, M Ford, D Yang… - Drug metabolism and …, 2004 - Elsevier
… In addition, treatment with dihydromethysticin, desmethoxyyangonin, or pregnenolone 16α-carbonitrile (PCN) markedly increased the levels of CYP3A23 mRNA, and inhibition of mRNA …
200444 citationsRegulation of cytochrome P450-3A (CYP3A) and pregnane X receptor (PXR): Implications to drug-drug interactions
K Sachdeva - 2005 - digitalcommons.uri.edu
… (CFA), also known as peroxisome proliferators; pregnenolone 16a carbonitrile (PCN), a known … increases the induction of CYP3A23 by pregnenolone 16a carbonitrile", we hypothesize …
2005Role of dehydroepiandrosterone in high-density lipoprotein-mediated vasodilation and in adipose tissue steroid biosynthesis
H Paatela - 2016 - helda.helsinki.fi
… enzyme converts cholesterol to pregnenolone (Koritz and Kumar 1970, Miller and Auchus 2011). Pregnenolone is sequentially converted to 17-hydroxypregnenolone and then to DHEA …
2016phenobarbital-induced rat liver microsomes. Using BCA labeled with'C and" Cin either the cyclopropyl ring or the benzylic carbon in conjunction with" C NMR and …
TS Dowers, DA Rock, JP Jones - search.ebscohost.com
… Plasma AA concentrations were significantly lower in HIV-positive patients not taking AA supplements (285: 237 M), compared to healthy controls (446 i 210), and patients taking 500-…
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-09-25. DSLD Label ID: 25236. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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