Brand: Karuna

CapsuleNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

120 Capsule(s)

Serving Size

1–4 Capsule(s)

Servings Per Container

120

Supplement Form

Capsule

Bar Code (UPC/SKU)

0 18647 08109 2

Product Version

8109-LB5

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Milk
  • Wheat
  • Soy

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1–4 Capsule(s) · 1 per day

IngredientAmount Per Serving
Pregnenolone50 mg—

Not Present

Other Ingredients

Rice Flour

Target Groups

Adult (18 - 50 Years)Dairy FreeSugar Free

Label Claims

All Other

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested use for adults: 1-4 capsules per day in divided doses with meals, or as directed by your health care practitioner.

Warnings & Precautions

Precautions re: Children

Caution: Not for use by individuals under the age of 18 years.

Precautions re: Children

Keep out of reach of children.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Storage

Storage

Keep in a cool, dry place, tightly capped.

Formulation

Formulation re: Does NOT Contain

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

FDA Statements

FDA Statement of Identity

Dietary Supplement

Other Label Statements

Seals/Symbols

KARUNA(R) RESPONSIBLE NUTRITION(TM)

General Statements: All Other Content

Steroid Hormone Precursor

General Statements: All Other Content

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

General: Product/Version Code

8109-LB5

Manufacturer & Distributor

Manufacturer

Karuna Corporation

42 Digital Drive #7, Novato, CA, 94949

Market Reference

$4.15 – $80.99· 40 listings
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    $43.20
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    $53.99
  • Karuna Progesterone Plus Cream

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    $54.60
  • Horbaach Pregnenolone 100mg 180 Capsules

    Target5.0(5)
    $17.99
  • Pure Encapsulations Pregnenolone mg

    Pure Prescriptions4.8(158)
    $14.50
  • Nootropics Depot Pregnenolone Tablets Quick Dissolve Micronized 365ct. 5mg

    Nootropics Depot4.6(12)
    $39.99
  • BulkSupplements Pregnenolone Capsules

    Target4.6(11)
    $17.97
  • Pregnenolone 25 mg 60 Tablets

    Life Extension4.3(25)
    $31.50

Where to Buy Locally

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Research & Studies

  • Pregnenolone 50mg Micronized Lipid Matrix

    WI Does, HI Works - fullscript.com

    … Pregnenolone is a neurosteroid and hormone precursor that plays a vital role in the production of … Pregnenolone helps bridge the gap between hormone synthesis and brain health, …

  • GABAergic neuroactive steroid response to sertraline in premenstrual dysphoric disorder

    KN Miller, L Standeven, AL Morrow, JL Payne… - …, 2024 - Elsevier

    Rationale Premenstrual dysphoric disorder (PMDD) affects approximately 5% of menstruating individuals, with significant negative mood symptoms in the luteal phase of the menstrual …

    202424 citations
  • Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23

    Y Ma, K Sachdeva, J Liu, M Ford, D Yang… - Drug metabolism and …, 2004 - Elsevier

    … In addition, treatment with dihydromethysticin, desmethoxyyangonin, or pregnenolone 16α-carbonitrile (PCN) markedly increased the levels of CYP3A23 mRNA, and inhibition of mRNA …

    200444 citations
  • Regulation of cytochrome P450-3A (CYP3A) and pregnane X receptor (PXR): Implications to drug-drug interactions

    K Sachdeva - 2005 - digitalcommons.uri.edu

    … (CFA), also known as peroxisome proliferators; pregnenolone 16a carbonitrile (PCN), a known … increases the induction of CYP3A23 by pregnenolone 16a carbonitrile", we hypothesize …

    2005
  • Role of dehydroepiandrosterone in high-density lipoprotein-mediated vasodilation and in adipose tissue steroid biosynthesis

    H Paatela - 2016 - helda.helsinki.fi

    … enzyme converts cholesterol to pregnenolone (Koritz and Kumar 1970, Miller and Auchus 2011). Pregnenolone is sequentially converted to 17-hydroxypregnenolone and then to DHEA …

    2016
  • phenobarbital-induced rat liver microsomes. Using BCA labeled with'C and" Cin either the cyclopropyl ring or the benzylic carbon in conjunction with" C NMR and …

    TS Dowers, DA Rock, JP Jones - search.ebscohost.com

    … Plasma AA concentrations were significantly lower in HIV-positive patients not taking AA supplements (285: 237 M), compared to healthy controls (446 i 210), and patients taking 500-…

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-09-25. DSLD Label ID: 25236. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.