SAMe 200 mg®

Other Combinations

Brand: Jarrow Formulas

Tablet or PillOther CombinationsOff Market
Click to view full label

Net Contents

60 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

60

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 90011 20016 1

Product Version

01420SAM60 PROD # 120016

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

3Dietary Attributes

Label states: Vegan, Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Wheat

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1–2 per day

IngredientAmount Per Serving
S-Adenosyl Methionine(SAM-e Tosylate Disulfate)200 mg

Not Present

Other Ingredients

CelluloseMannitolGlyceryl BehenateMagnesium StearateSilicon DioxideSodium Starch GlycolateEnteric Coating

Target Groups

VeganVegetarianAdult (18 - 50 Years)Women (not pregnant or lactating)Gluten FreeDairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Usage: Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.

Suggested/Recommended/Usage/Directions

For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product.

Precautions re: All Other

Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Precautions re: All Other

Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Precautions re: Children

Keep out of the reach of children.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Other

Full potency

Formula re: Contains

Full potency 200 mg SAMe (net yield) is derived from 400 mg of SAMe tosylate disulfate.

Formulation re: Other

pH-sensitive - food grade enteroguard coating

Formula re: Contains

S-Adenosyl Methionine 200 mg (net yield) SAMe from 400 mg SAMe tosylate disulfate Highest concentration of Active S,S Form

Formulation re: Other

Promotes: Joint strength Liver detoxification Mood and brain function

Formulation re: Other

Enteric-coated tablets

Formulation re: Vegetarian/Vegan

V Vegan

Formulation re: Vegetarian/Vegan

Suitable for vegetarians/vegans.

Formulation re: Does NOT Contain

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.

Formulation re: Other

EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

Formula re: Contains

Jarrow Formulas SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains more of the active S,S form Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.

Formulation re: Other

SAMe has been clinically shown to have the following benefits: Joint Strength SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate. Brain Metabolism SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin). Liver SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification.

FDA Statements

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other Label Statements

General Statements: All Other Content

Jarrow Formulas SAMe 200 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.

Brand IP Statement(s) re: (c), (TM), (SM)

2020 Jarrow Formulas

Manufacturer & Distributor

Distributor

Jarrow Formulas Superior Nutrition and Formulation

Los Angeles, CA, 90035-4317

(866) 459-4154

Market Reference

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Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • William's Natural Foods

    4.7 (126)

    Vitamin & supplements store

    12249 San Pablo Ave, Richmond, CA 94805

  • B Zen Botanicals | Herbs, Superfoods & Loose Leaf Teas

    5.0 (34)

    Health food store

    6033 Front St, Georgetown, CA 95634

  • Walgreens

    3.1 (84)

    Vitamin & supplements store

    3601 California St, San Francisco, CA 94118

  • 3M Mom, Pop & Sons Market

    2.7 (54)

    Grocery store

    1205 Fred Jackson Way, Richmond, CA 94801

  • Walgreens

    2.9 (60)

    Vitamin & supplements store

    22 San Pedro Rd, Daly City, CA 94014

  • Walgreens

    2.8 (112)

    Vitamin & supplements store

    2238 Westborough Blvd, South San Francisco, CA 94080

  • Walgreens

    3.0 (165)

    Vitamin & supplements store

    2300 Otis Dr, Alameda, CA 94501

  • Walgreens

    1.8 (382)

    Vitamin & supplements store

    1414 El Camino Real, San Carlos, CA 94070

Research & Studies

  • Efficacy of the Dietary Supplement S-Adenosyl-L-Methionine

    CW Fetrow, JR Avila - Annals of Pharmacotherapy, 2001 - journals.sagepub.com

    … injection with SAMe (200 mg at 0800 and 200 mg at 2400) … received 800 mg/d of oral SAMe (400 mg at 0800 and 400 mg at … supplement in the US under the Dietary Supplement Health …

    200163 citations
  • Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes

    P Orlando, S Silvestri, R Galeazzi, R Antonicelli… - Redox …, 2018 - Taylor & Francis

    … Distribution of average speed (A) and total time of run conducted at values equal and above … wish to thank Jarrow Formulas for kindly providing ubiquinol (QH absorb 200 mg) and …

    201893 citations
  • Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia

    E Teran, I Hernandez, B Nieto, R Tavara… - International Journal of …, 2009 - Elsevier

    … Women were assigned to receive 200 mg of CoQ10 or placebo … capsules produced by the same manufacturer. Both products were … were provided free of charge by Jarrow Formulas Inc. …

    2009175 citations
  • Utility of nutraceutical products marketed for cognitive and memory enhancement

    GJ McDougall Jr, V Austin-Wells… - Journal of Holistic …, 2005 - journals.sagepub.com

    … With the increased interest in nutraceuticals, medical and allied health care … Sam-e is used as a nutritional supplement in the treatment of AIDS-… S-adenosyl methionine 200 mg …

    200519 citations
  • Accumulation of sulforaphane and alliin in human prostate tissue

    TL Livingstone, S Saha, F Bernuzzi, GM Savva… - Nutrients, 2022 - mdpi.com

    … broccoli (BroccoMax ® , Jarrow Formulas, Los Angeles, CA, … urine and prostate tissue samples using the same methods. … result in local effects on healthy and cancerous cells through a …

    202232 citations
  • Ipriflavone for prevention of osteoporosis

    JL Balk - Alternative Medicine Alert, 2000 - clinician.com

    … 200 mg tid, for a total daily dosage of 600 mg, although a 300 mg tablet bid appears to have the same … Ipriflavone is available on the Internet, through mail-order catalogs, in health food …

    20002 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-02-25. DSLD Label ID: 243544. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.