SAM-e 200 mg®
Non-Nutrient / Non-BotanicalBrand: Jarrow Formulas
Net Contents
60 Enteric Coated Tablet(s) in Foil Blister Pack
Serving Size
1–2 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 90011 20016 1
Product Version
0509SAM60 PROD # 120016
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Milk
- Egg
- Fish
- Peanut
- Wheat
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1–2 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl Methionine(SAM-e Tosylate Disulfate) | 200 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
USAGE: Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health care consultant.
Warnings & Precautions
Precautions re: All Other
WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e.
Precautions re: Children
Keep out of the reach of children.
Storage
Storage
Store in a cool, dry place.
Formulation
Formula re: Contains
200 mg (net yield) SAM-e from 400 mg SAM-e tosylate disulfate
Formulation re: Does NOT Contain
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans.
FDA Statements
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
(C) 2009 Jarrow FORMULAS(R)
Brand IP Statement(s) re: (c), (TM), (SM)
For best results , use with Jarrow FORMULAS(R) JarroSil(TM), the biologically Activated Silicon(TM).
Brand IP Statement(s) re: (c), (TM), (SM)
Jarrow FORMULAS(R) pharmaceutical grade, stabilized SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Brand IP Statement(s) re: (c), (TM), (SM)
Jarrow FORMULAS(R) SAM-e 200 is foil blister-packed to maximize stability and safety. DO NOT use if outer seal of blister pack is broken.
General: Product/Version Code
0509SAM60 PROD # 120016
General Statements: All Other Content
Contains More of the Active S,S Form
General Statements: All Other Content
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow FORMULAS(R) SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available. SAM-e has been clinically shown to have the following benefits: Joint Strength SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.* Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).* Longevity Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process.* Proper methylation through substances such as SAM-e positively influences longevity.* Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione -dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.*
General Statements: All Other Content
FULL POTENCY
General Statements: All Other Content
Full Potency 200 mg SAM-e is derived from 400 mg of SAM-e tosylate disulfate.
General Statements: All Other Content
Highest Concentration of Active S,S Form
General Statements: All Other Content
Natural SAM-e 200
General Statements: All Other Content
Pharmaceutical Grade, Stabilized
General Statements: All Other Content
PRODUCT OF ITALY
General Statements: All Other Content
Promotes: Longevity* Joint Strength* Liver Detoxification* Mood and Brain Function*
General Statements: All Other Content
SAM-e S-Adenosyl Methionine 200
General Statements: All Other Content
This product complies with the proposed USP Monograph for SAM-e.
Manufacturer & Distributor
Other
Jarrow Formulas, Inc.
P.O Box 35994, Los Angeles, CA, 90035
Manufacturer
Jarrow Formulas
Los Angeles, CA, 90035-4317
Market Reference
Jarrow Formulas SAM-e 200 mg Tablets
Fruitful Yield4.6(444)$44.99Jarrow Formulas Same 200 mg - 60 Tablets - Highest Concentration of Active S S Form - Supports Joint Health Liver Function Brain Metabolism Mood &
GoSupps.com$69.99SAM‐e 200 mg – Pharmaceutical‐Grade Mood & Joint Support Doctors Buy 3 Bottles 30 Save
Edom Laboratories$101.03Nature Made SAM-e Complete 400 mg
Walmart - Nature Made4.5(310)$37.31LowestJarrow Formulas - QH-Absorb 200mg - 30 Softgels
Pure Prescriptions4.8(2400)$60.99Jarrow Formulas QH-Absorb
Village Green Apothecary4.8(2400)$42.74Klaire Labs SAMe 200 Hypoallergenic S-adenosylme
Blue Sky Vitamin5.0(1)$59.99Jarrow Formulas Resveratrol Synergy 200 mg. 60 Tablets
personalpower4.0(4)$39.95
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4.5 (203)Vitamin & supplements store
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Research & Studies
Utility of nutraceutical products marketed for cognitive and memory enhancement
GJ McDougall Jr, V Austin-Wells… - Journal of Holistic …, 2005 - journals.sagepub.com
… Sam-e is a shortening of the technical name and is trademarked under this name. Sam-e is used as a nutritional supplement … One study indicated that Sam-e was superior to a placebo …
200519 citationsThe SAM-e Solution: The Essential Guide to the Revolutionary Antidepression Supplement
D Mitchell - 2000 - books.google.com
… SAM-e levels are characteristic of many different medical conditions, which are discussed at length in this book. They also found that levels of SAM-e … blood levels of SAM-e than women, …
20004 citationsDietary supplements: Evaluation and application in clinical practice
CA Thomson, T Newton - Topics in Clinical Nutrition, 2005 - journals.lww.com
… (1160 mg/d), St John's wort (900 mg/d), vitamin E (800 IU/d), melatonin (2.5 mg/d), and SAM-e (200 mg/d). … Likewise, SAM-e was shown to be effective in the treatment of osteoarthritis. …
20059 citationsAlternative Preparations and Over-the-Counter Drugs
MOG Debiasi - Psychiatric Nursing-eBook: Psychiatric Nursing …, 2018 - books.google.com
… often contain 200 mg of … supplement in 1999, S -adenosyl- L -methionine (SAM-e) is widely used in Europe and Canada; in fact, it is available as a prescription drug in Germany. SAM-e …
2018First St. John's Wort, Now SAM-e: Is Society as a Whole at Risk without FDA Regulation of Psychiatric Self-Medication
LM Diaz - Kan. JL & Pub. Pol'Y, 1999 - HeinOnline
… have undergone studies comparing SAM-e with placebos or with anti-… SAM-e holds promising possibilities for persons suffering from arthritis. SAM-e is sold as a dietary supplement …
19992 citations… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… event profile similar to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e Complete based on area under …
202014 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2011-10-26. DSLD Label ID: 1131. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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