5-MTHF 1 mg

Suggested Use

Suggested use: Take one capsule daily or as directed by a physician or a healthcare provider.

• 

  Intelligent Labs 1MG 5-MTHF Methylfolate 120 Capsules 4 Months Supply

  Intelligent Labs5.0(4)

  $23.99
• 

  5MG L-5 MTHF By Intelligent Labs L-5 Methylfolate Activated Folic Acid Supplement as Quatrefolic Acid

  Intelligent Labs

  $36.99
• 

  Intelligent Labs 5-MTHF 5 mg 60 Vegetarian Capsules

  iHerb4.9(29)

  $36.99
• 

  Thorne 5-MTHF 1 mg 60 Capsules

  Target4.8(2000)

  $24.00
• 

  5-MTHF 1 mg 60 capsules

  Life Extension4.8(2000)

  $24.00
• 

  5-MTHF 1MG by Nedley Health - Supports Heart & Cellular Health

  Nedley Health

  $26.99
• 

  DaVinci Labs 5-MTHF 1 mg 60 Capsules

  Pine Street Clinic4.8(13)

  $28.12
• 

  5-MTHF 1mg 120 Capsules

  Discount Health Products3.0(2)

  $21.07

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• Akeso Health Sciences, LLC

  1.0 (1)

  Vitamin & supplements store

  4607 Lakeview Canyon Rd #561, Westlake Village, CA 91361

  Directions(800) 758-8746

• Conversion of calcium‐l‐methylfolate and (6S)‐5‐methyltetrahydrofolic acid glucosamine salt into dietary folate equivalents

  EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2022 - Wiley Online Library

  … ANS) 13 assessed (5-MTHF-glucosamine and proposed it as an alternative source of folate to be used in food supplements up to 1.8 mg/day (ie 1 mg 5-MTHF and 0.8 mg glucosamine). …

  202221 citations

• Folic acid, folinic acid, 5 methyl tetrahydrofolate supplementation for mutations that affect epigenesis through the folate and one-carbon cycles

  Y Menezo, K Elder, A Clement, P Clement - Biomolecules, 2022 - mdpi.com

  … FA after supplementation. UMFA … health, as will be further described here [3]. We will outline a rationale for replacing folic acid supplementation (especially at high doses) with 5-MTHF…

  2022243 citations

• Supplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review

  ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com

  … Regarding Hcy, total plasma Hcy levels decreased significantly in both subjects receiving 1 mg FA or 5-MTHF over time; however, no differences in total Hcy levels nor abortion rates …

  202425 citations

• Effect of nutritional supplements for reducing homocysteine levels in healthy adults: a systematic review and network meta-analysis of randomized trials

  C Liu, H Yao, F Wang - Nutrition Reviews, 2025 - academic.oup.com

  … demonstrate the advantage of 5-MTHF in healthy adults: we … and supplements evaluated in this study, 1 mg of FA plus 7.2 mg of B 6 … on this particular combination among healthy adults. …

  202510 citations

• 5-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial

  R Vukotic, R Di Donato, G Roncarati, P Simoni… - Journal of …, 2023 - Elsevier

  … 5-Methyltetrahydrofolate (5-MTHF) can prevent oxidative loss of tetrahydrobiopterin (BH4), a … The aim of this study was to evaluate the effects of 5-MTHF in combination with propranolol …

  202315 citations

• … of Folate Forms Following Supplementation of Multimicronutrients with 400 µg or 800 µg Mix of (6S)‐5‐Methyltetrahydrofolate and Folic Acid (1: 1) in Women of …

  R Obeid, E Rube, C Schön… - Molecular Nutrition & Food …, 2024 - Wiley Online Library

  … health outcomes. [ 17-21 ] For example, a study in women with epilepsy has shown that taking ≥1 mg day −1 FA … 400 or 800 µg day −1 of a mixture of 1:1 (6S)-5-MTHF-Ca and FA (thus …

  20242 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-05-21. DSLD Label ID: 329227. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.