Shiitake Extract® ™

Non-Nutrient / Non-Botanical

Brand: Host Defense Mushrooms

LiquidNon-Nutrient/Non-BotanicalOn Market

Functions

Immune Support

Product label for Shiitake Extract — Click to view full label

Net Contents

2 fl. Oz.

Serving Size

1 mL

Servings Per Container

Supplement Form

Liquid

Bar Code (UPC/SKU)

Not specified

Product Version

NXLE2 REV A2

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Label includes a proprietary blend, so some individual amounts are not itemized.

2Dietary Attributes

Label states: Organic, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 mL · 2 per day

Ingredient	Amount Per Serving
Proprietary Blend	1 mL	—
fresh Shiitake (Lentinula edodes) mycelium extract	—	—
dried Shiitake (Lentinula edodes) fruitbody extract	—	—

Not Present

Other Ingredients

WaterAlcoholmyceliated Brown Rice

Target Groups

Adult (18 - 50 Years)OrganicGluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions for Use: As a dietary supplement, take 1 mL twice per day. Can be taken with food or without, on an empty stomach or as recommended by your healthcare advisor. Shake well before using, refrigerate after opening.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Consult your healthcare advisor regarding the use of this product during pregnancy.

Precautions re: Children

Keep out of reach of children.

Storage

Shake well before using, refrigerate after opening.

Formulation

Formula re: Contains

Made with U.S. grown, triple extracted organic mushroom mycelium and fruitbodies

Formulation re: Does NOT Contain

Gluten free

Formulation re: Organic

Certified Organic by the Washington State Department of Agriculture.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Other Label Statements

General: Product/Version Code

NXLE2 REV A2

Seals/Symbols

USDA Organic

General Statements: All Other Content

Immune support

Seals/Symbols

Producer Certified Organic Washington State Dept. of Agriculture

Manufacturer & Distributor

Manufacturer

Fungi Perfecti, LLC

PO Box 7634, Olympia, WA, 98507, USA

877-504-6926

Market Reference

$9.99 – $119.99· 40 listings

Nature's Answer Shiitake Fruiting Body Extract
Walmart - Natures Answer4.4(63)
$11.99
Fungi Perfecti Host Defense Mushrooms Breathe Extract
Target4.6(35)
$15.71
Swanson Shiitake Mushroom Extract 500 mg 120 Caps
Swanson Health Products4.8(101)
$15.49
Host Defense MyCommunity
Walgreens.com4.8(956)
$38.99
HPD Rx Premium AHCC & Shiitake Mushroom Supplement
HPD Rx
$59.99
Shiitake Tincture
Foraged
$25.00
Carlyle Shiitake Mushroom Extract 3000mg 200 Capsules
Target5.0(1)
$14.99
PSK Shiitake Mushroom Extract Mushroom Supplements
Walmart - BulkSupplements.com4.4(22)
$33.97

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

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House of Gains Fitness Outlet - York
5.0 (239)
Vitamin & supplements store
1276 Greensprings Dr, East York, PA 17402
Directions (223) 284-7791
The Vitamin Shoppe
4.7 (97)
Vitamin & supplements store
415 Loucks Rd, York, PA 17404
Directions (717) 846-6192
Natural Foods by Allen
4.4 (29)
Vitamin & supplements store
350 S Richland Ave, York, PA 17404
Directions (717) 845-8085
NutraBoost
Vitamin & supplements store
740 W Clearview Dr d, Glen Rock, PA 17327
Directions
Enchanted Herbal
4.9 (67)
Herbal medicine store
2900 Carlisle Rd, Dover, PA 17315
Directions (717) 324-0179
GNC
3.9 (17)
Vitamin & supplements store
648 Shrewsbury Commons Ave, Shrewsbury, PA 17361
Directions (717) 227-2111
Nature's Corner
5.0 (1)
Herbal medicine store
4 Baneberry St, Stewartstown, PA 17363
Directions (443) 545-6396
Sonnewald Natural Foods
4.6 (534)
Natural goods store
4796 Lehman Rd, Spring Grove, PA 17362
Directions (717) 225-3825

Research & Studies

The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and …
MS Shin, HJ Park, T Maeda, H Nishioka… - Journal of …, 2019 - Wiley Online Library
… AHCC® is a standardized extract of cultured shiitake or … T cells given their roles in host defense and inflammation [29–34], … and possibly other medical mushrooms in health and disease. …
201951 citations
Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts
V Vetvicka, J Vetvickova - Annals of translational medicine, 2014 - pmc.ncbi.nlm.nih.gov
… The Maitake mushroom extract used in our study is rich in β-… Shiitake mushroom used in this study is an alpha glucan-rich whole mushroom powder obtained from Gourmet Mushrooms, …
2014127 citations
The shiitake mushroom-derived immuno-stimulant lentinan protects against murine malaria blood-stage infection by evoking adaptive immune-responses
L Zhou, Q Zhang, Y Zhang, J Liu, Y Cao - International …, 2009 - Elsevier
… Lentinan, a (1-3)-beta-d-glucan extracted from the mushroom Lentinus edodes, is used as an immuno-modulator in clinical practice [1], [2]. Its immuno-stimulatory effects range from …
2009133 citations
Supplementation with a Soluble Beta-Glucan Exported from Shiitake Medicinal Mushroom, Lentinus edodes (Berk.) Singer Mycelium: a Crossover, Placebo …
JM Gaullier, J Sleboda, ES Ofjord… - … mushrooms, 2011 - dl.begellhouse.com
… were analyzed to screen healthy subjects for alanine amino … These analyses were also performed at each medical visit … immune cells involved in host defense mechanisms.Beta-glucans …
201179 citations
The Role of Edible Mushrooms in Immune Support
EO Akhigbe, SC Izah, OI Ogidi, AA Iyingiala… - … in Edible Mushrooms …, 2025 - Springer
… Shiitake mushrooms are one of the few natural food sources of vitamin D. Adequate … Many mushroom products contain extracts or bioactive phytoconstituents that have powerful antican…
202511 citations
Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults
X Dai, JM Stanilka, CA Rowe, EA Esteves… - Journal of the …, 2015 - Taylor & Francis
Background: Mushrooms are widely cited for their medicinal … Lentinula edodes (shiitake) mushrooms could improve human … Design: Fifty-two healthy males and females, aged 21–41 …
2015217 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-02-25. DSLD Label ID: 200108. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.