SAM-e 400 mg™

Other Combinations

Brand: HBC Protocols

Tablet or PillOther CombinationsOn Market

Functions

Sleep, Mood & Stress

Product label for SAM-e 400 mg — Click to view full label

Net Contents

60 Tablet(s)

Serving Size

1–4 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

Not specified

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

4Active Ingredients

4 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1–4 Tablet(s) · 1 per day

Ingredient	Amount Per Serving
S-Adenosyl-Methionine Disulfate Tosylate	400 mg	—
Vitamin B6	2 mg	—
Vitamin B12	50 mcg	—
Folic Acid	200 mcg	—

Not Present

Other Ingredients

S-Adensoyl MethionineMicrocrystalline CelluloseMagnesium StearateTalcMetocrylic Copolymer

Target Groups

Adult (18 - 50 Years)

Label Claims

Structure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions For Use: Adults take 1 - 4 tablets daily or as directed by your physician.

Formulation

Formula re: Contains

S-adenosyl-Methionine Disulfate Tosylate

FDA Statements

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

SAMe is a naturally derived product which helps support positive mood balance. It has been shown to support glutathione production which helps support the body's antioxidant system and healthy liver function, as well as mitigate dangerous levels of homocysteine.

Manufacturer & Distributor

Manufacturer

HBC Protocols, Inc.

8205 Santa Monica Blvd. Suite 472, Los Angeles, California, 90046

888.497.3742

Market Reference

$9.18 – $105.00· 26 listings

Nature Made SAM-e Complete 400 mg
Walmart4.6(190)
$52.97
Walgreens Sam-e 400 mg Coated Caplets
Walgreens.com
$49.99
Jarrow Formulas SAM-e 400 60 Tablets
Whole Foods Market4.7(430)
$50.49
Doctor's Best SAMe 400 mg Double Strength Enteric Coated Tablets
Target4.7(771)
$52.99
Protocol For Life Balance SAMe 400mg 60 Tablets
boulevardcompounding.com4.9(35)
$73.99
Nature Made Vitamin E
HealthWarehouse.com4.7(594)
$13.40
SAM-e 400mg
aSquared Nutrition
$39.95
SuperSmart SAM-e 400mg
SuperSmart USA4.7(49)
$105.00

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

GNC
4.4 (88)
Vitamin & supplements store
753 Broadway Spc 753, New York, NY 10003
Directions (212) 380-5999
The Vitamin Shoppe
4.3 (163)
Vitamin & supplements store
385 5th Ave, New York, NY 10016
Directions (212) 532-4534
GNC
3.6 (143)
Vitamin & supplements store
549 6th Ave, New York, NY 10011
Directions (212) 924-5925
Pure Essentials Supplements
5.0 (1)
Vitamin & supplements store
121 Varick St, New York, NY 10013
Directions (212) 758-3200
The Vitamin Shoppe
4.4 (98)
Vitamin & supplements store
257 8th Ave, New York, NY 10011
Directions (212) 243-0086
GNC
4.0 (224)
Vitamin & supplements store
134-136 Fulton St, New York, NY 10038
Directions (212) 374-9473
GNC
4.7 (197)
Vitamin & supplements store
2 Pennsylvania Plaza Ste 29B, New York, NY 10121
Directions (212) 239-1251
The Vitamin Shoppe
4.5 (143)
Vitamin & supplements store
NW corner of 55th & 8th, 931 8th Ave, New York, NY 10019
Directions (212) 582-8965

Research & Studies

… of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement …
BR Cameron, L Ferreira, ID MacDonald - BMC Pharmacology and …, 2020 - Springer
… MSI discovered that formulations of SAM-e including propyl gallate have enhanced … has a dosage strength of 400 mg (based on the weight of the free base). The SAM-e counter-ions are …
202014 citations
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
Background/Objectives: S-adenosylmethionine (SAMe) is a natural compound used to improve mood-related symptoms. Our aim was to determine the efficacy, safety, and optimal dose …
202410 citations
13 Liver Disease
R Heuberger - Integrating Therapeutic and Complementary Nutrition - docuri.com
… are 400–800 mg= day, and SAM-e has also been purported to be useful in promoting joint health and … for the determination of hepatotoxicity with dietary supplements. The research …
The SAM-e Solution: The Essential Guide to the Revolutionary Antidepression Supplement
D Mitchell - 2000 - Hachette+ ORM
20004 citations
The Methylation Miracle: Unleashing Your Body's Natural Source of SAM-e
P Frankel, N Bruning - 1999 - Macmillan
19994 citations
The Indianapolis-Ibadan Dementia Project
HC Hendrie - 2001 - search.proquest.com
… As pointed out in the World Health Organization (WHO) protocol for Research on Aging sampling, an entire village or well-defined area offers the advantage of clear structural …
200110 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-06-23. DSLD Label ID: 74981. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.