Brand: GNC

Tablet or PillNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

30 Tablet(s)

Serving Size

1–2 Tablet(s)

Servings Per Container

30

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

Not specified

Product Version

CODE 130911 KHG

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1–2 Tablet(s) · 2–4 per day

IngredientAmount Per Serving
SAM-e(Disulfate Monotosylate)400 mg

Not Present

Other Ingredients

Microcrystalline CelluloseCroscarmellose SodiumMethacrylic Acid Co-PolymerSilicon Dioxide, ColloidalMagnesium StearateTriethyl CitrateStearic AcidCitric AcidAscorbic AcidRiboflavin

Target Groups

Adult (18 - 50 Years)

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions For Adult Use Only: As a dietary supplement, take one tablet in the morning and one tablet in the afternoon for the first week. If after the first week the desired benefits are not achieved, then you may require a higher level of supplementation. Gradually increase the number of tablets up to four tablets in divided doses of two tablets (800 mg) throughout the day until benefits are achieved. Do not exceed four tablets daily.

Warnings & Precautions

Precautions re: All Other

CAUTION: Do not use if tamper-evident printed foil seal over tablets is broken.

Precautions re: Children

KEEP OUT OF REACH OF CHILDREN.

Precautions re: Pregnant or Nursing or Prescription Medications

WARNING: Do not use if pregnant or nursing. If you are taking prescription antidepressant medications, consult your physician before using this product, individuals with bipolar (manic) depression should not use this product unless under medical supervision.

Storage

Storage

Store in a cool, dry place.

Formulation

Formula re: Contains

(s-adenosyl-methionine)

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Other Label Statements

General Statements: All Other Content

400 mg

General Statements: All Other Content

A report published by the US Department of Health and Human Services suggest that SAM-e provides clinically significant health benefits for individuals seeking mood support (1600 mg daily), joint comfort and healthy liver function (1200 mg daily). SAM-e provides mood support, as well as, relief to joint discomfort, and these benefits are comparable to conventional therapies.

General Statements: All Other Content

clinically proven benefits for mood and joint support and healthy liver function

General: Product/Version Code

CODE 130911 KHG

General Statements: All Other Content

ENTERIC COATED

General Statements: All Other Content

For more information:

General Statements: All Other Content

Made in the USA

General Statements: All Other Content

SHOP NOW

Manufacturer & Distributor

Distributor

General Nutrition Corporation

Pittsburgh, PA, 15222

1-888-462-2548

Market Reference

$15.91 – $105.00· 23 listings
  • GNC 180 Softgels

    GNC4.8(34)
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  • GNC Isomer E 400 Iu

    GNC4.8(33)
    $29.99
  • Nature Made SAM-e Complete 400 mg

    Walmart4.5(310)
    $53.98
  • Carlyle SAM-e 400mg 30 Tablets

    Target4.5(6)
    $20.99
  • Jarrow Formulas SAM-e 400 60 Tablets

    The Healthy Place4.7(442)
    $44.19
  • Doctor's Best SAMe 400 mg Double Strength Enteric Coated Tablets

    Walmart4.7(792)
    $52.42
  • SuperSmart SAM-e 400mg

    SuperSmart USA4.7(50)
    $105.00
  • NOW Foods Sun-E 400 Softgels

    NOW4.7(228)
    $49.99

Where to Buy Locally

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Research & Studies

  • Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity

    RP Brown, PL GERBARG - Journal of Psychiatric Practice, 2001 - ovid.com

    … (40 of whom were medically hospitalized) compared SAM-e 400 mg IV to SAM-e 800 mg po … made by the original manufacturer in Italy: Nature Made, GNC, and Actimet SAM-e (carried …

    200158 citations
  • SAMe (S-adenosyl-l-methionine)

    M Brula, MJ Cupp, TS Tracy - … Supplements: Toxicology and Clinical …, 2003 - Springer

    … Study duration ranged from 21 to 730 d, and dosages ranged from 400 mg/d to 400 mg three … The facts on the nutritional supplement SAM-e. Available from:URL: http:// content.health.…

    2003
  • Fibromyalgia Basics: A Beginner's Guide

    P Chandler - 2011 - books.google.com

    … Some physicians may recommend an overthe-counter antidepressant called Sam-e, short for S-adenosylmethionine.20 In Europe, Sam-e is a prescription medication, and physicians …

    20112 citations
  • The Definitive Guide to Natural Pregnancy Health-Why Your Prenatal Vitamin May Not Be Enough

    T Comeaux - 2007 - books.google.com

    … of different supplements, lists common problems that she has encountered in her practice, and details the maximum amount of each supplement to be taken during a healthy pregnancy. …

    20073 citations
  • What about supplements for osteoarthritis? A critical and evidenced‐based review

    ES Vista, CS Lau - International Journal of Rheumatic …, 2011 - Wiley Online Library

    … 2800 mg and chondroitin 865 mg Two capsules daily GNC SAM-e 200 S-adenosyl-methionine 200 mg 2–… Piasclédine Avocado/soybean unsaponifiables 300 mg tablet One tablet daily …

    201153 citations
  • SAMe (S-adenosyl-L-methionine)

    VYR Profile, MP Finder

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2011-10-26. DSLD Label ID: 666. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.