St. John's Wort®
Botanicals & HerbsBrand: GNC Herbal Plus Standardized
Functions
Net Contents
200 Vegetarian Capsule(s)
Serving Size
1–3 Capsule(s)
Servings Per Container
Not specified
Supplement Form
Capsule
Bar Code (UPC/SKU)
0 48107 06480 8
Product Version
CODE 194521 JFG
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Milk
- Wheat
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1–3 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| St. John's Wort Herb Extract | 300 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one to three capsules daily.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Precautions re: All Other
Discontinue use two weeks prior to surgery. Use of this product may cause your skin to be extra sensitive to UV sources such as artificial or natural sunlight. Avoid excessive exposures from these sources.
Precautions re: Children
KEEP OUT OF REACH OF CHILDREN
Storage
Storage
Store in a cool, dry place.
Formulation
Formula re: Contains
300 mg - 0.3% Hypericin
Formulation re: Does NOT Contain
No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.
FDA Statements
FDA Statement of Identity
HERBAL SUPPLEMENT
FDA Disclaimer Statement
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Other Label Statements
General Statements: All Other Content
Made in the USA
Brand IP Statement(s) re: (c), (TM), (SM)
GNC HERBAL PLUS(R) STANDARDIZED
General Statements: All Other Content
Promotes Positive Mood Balance*
General Statements: All Other Content
CODE 194521 JFG
General Statements: All Other Content
Potency verified by GNC procedure #5286. Conforms to USAP <2091> for weight. Meets USP <2040> disintegration.
General Statements: All Other Content
Lot No./Best By:
Manufacturer & Distributor
Other
1-888-462-2548
Other
Distributor
General Nutrition Corporation
Pittsburgh, PA, 15222
Market Reference
GNC Herbal Plus St. John's Wort Extract 300Mg
GNC4.4(36)$29.99GNC Herbal Plus Capsules
GNC4.3(17)$29.99GNC Herbal Plus Extract 150Mg 100 Capsules
GNC4.6(10)$17.99GNC Herbal Plus Energy Formula 100 Capsules
Walmart - Pattern4.4(131)$26.99Nature's Truth St. John's Wort
Target4.8(41)$12.99NaturesPlus Herbal Actives St John's Wort 450 mg
Vitacost.com4.6(92)$23.76Nature's Bounty St. John's Wort 300 mg
CVS Pharmacy4.6(194)$19.99St John's Wort Extract
Target4.7(246)$16.95
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Holland & Barrett - Carlisle
4.4 (9)Health food shop
2 Globe Ln, Carlisle CA3 8NX
Research & Studies
THE SUPPLEMENT SAGA: A Review of the New York Attorney General's Herbal Supplement Investigation.
T Smith - HerbalGram, 2015 - search.ebscohost.com
… to GNC and its Herbal Plus products, both the NY AG and GNC … John's wort and Echinacea--do not have publically available … Standardized herbal extracts are made by dissolving herbs …
20154 citationsVariable inhibitory effect of herbal supplements of different brands on human P450 CYP1A2
S Wanwimolruk, V Prachayasittikul - EXCLI journal, 2012 - pmc.ncbi.nlm.nih.gov
… The actual activities of CYP1A2 caused by all (except GNC Plus brand) BC herbal extracts … Testing of 28 brands of St. John's wort capsules revealed large variations in the total content …
20126 citationsThe Hypericum perforatum herb as an antimycobacterial agent and its implications as an additional tuberculosis medication
TW Mortensen - 2010 - search.proquest.com
… This research investigated the effectiveness of the Hypericum perforatum herb (commonly St. Johns wort (SJW)) in its growth inhibition of mycobacteria and its viability effect on human …
2010Issues in phytomedicine related to psychiatric practice
M Blumenthal - … and integrative treatments in psychiatric practice, 2017 - books.google.com
… For example, in Germany, herbs are sold primarily as … extraction and chemical standardization according to good … with retailer GNC, acknowledging that the herbal products were …
20171 citationsSompon Wanwimolruk*, Keldon Wong and Preeya Wanwimolruk'School of Pharmacy, Loma Linda University
S Wanwimolruk - researchgate.net
… (or slight activation) by GNC 100 mg to moderate inhibition of … John's wort capsules revealed large variations in the total … labeling information and standardized manufacturing practices …
Translational Case Studies on Marketed Phytomedicines: From Traditional Knowledge to Global Therapeutics
S Soni, S Rathee, M Tekade, A Bharti… - Biomolecular and …, 2026 - api.taylorfrancis.com
… John’s Wort St John’s wort extracts are becoming established as a standard antidepressant therapy due to their active ingredients, making it one of the most extensively investigated …
20262 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-02-25. DSLD Label ID: 18219. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.



