Net Contents
90 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
Not specified
Supplement Form
Capsule
Bar Code (UPC/SKU)
8 50012 95659 4
Product Version
Not specified
Suggested Use
Recommended DosageTake one (1) capsule daily with sufficient water before a meal.
Market Reference
Fresh Nutrition L Methyl Folate 7.5mg
Fresh Nutrition5.0(27)$20.995-MTHF 5 mg
ThorneVet$68.00Opti-Folate L Methyl Folate 7.5 mg 60 Capsules
Walmart - Carlyle Nutritionals, LLC4.6(37)$14.025 MTHF Methylfolate Supplement Capsules 1 Bottle
Indigo Health Clinic$49.00(2 pack) Best Naturals Methyl Folate 7500 mcg (7.5mg) 60 Capsules (Vegetarian Capsules), Size: 1.41 oz, White
Walmart - Best Naturals4.6(7)$26.985 MTHF - Betterlife Pharmacy NJ
Better Life Pharmacy$31.645-Mthf
eBay - josephson3$79.95NFH L 5-MTHF SAP 60 Capsules
Wellness Supplements3.0(2)$17.44
Where to Buy Locally
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Showing representative supplement & health retailers — search above for stores in your area.
GNC
4.1 (38)Vitamin & supplements store
1118 Commerce Ave, City of Atwater, CA 95301
Research & Studies
Effect of nutritional supplements for reducing homocysteine levels in healthy adults: a systematic review and network meta-analysis of randomized trials
C Liu, H Yao, F Wang - Nutrition Reviews, 2025 - academic.oup.com
… The preference for 5-MTHF supplementation during pregnancy over FA is attributed to its ability to … of 5-MTHF in healthy adults: we found that similar doses of FA and 5-MTHF yielded …
202510 citationsFolic acid, folinic acid, 5 methyl tetrahydrofolate supplementation for mutations that affect epigenesis through the folate and one-carbon cycles
Y Menezo, K Elder, A Clement, P Clement - Biomolecules, 2022 - mdpi.com
… due to potential adverse effects on health, as will be further … supplementation (especially at high doses) with 5-MTHF. … NTDs, nutritional supplementation with 5-MTHF can effectively …
2022243 citationsSupplementation with folic acid or 5-methyltetrahydrofolate and prevention of neural tube defects: an evidence-based narrative review
ML Samaniego-Vaesken, C Morais-Moreno… - Nutrients, 2024 - mdpi.com
… health challenge by many authors in the past decades [3,20]. To manage this issue, in 1998, the Food and Nutrition … -insufficient women given 7.5 mg daily doses of 5-MTHF than in the …
202425 citationsFolate in depression: efficacy, safety, differences in formulations, and clinical issues.
M Fava, D Mischoulon - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… 5-MTHF would have been a more appropriate supplement … States as a prescription medical food for depressed patients … as elderly people who have nutritional problems, individuals with …
2009265 citationsIdentification of potential histone deacetylase 3 inhibitors from fermented bamboo shoots using GC-MS metabolomics, molecular docking, pharmacokinetics and …
R Das, D Pradhan, A Kishore, R Singh, B Tamang - Food Bioscience, 2025 - Elsevier
… (5-MTHF) had prominent upregulation and tight association with pathways in lung cancer. Molecular docking analysis showed that 5-MTHF … of the HDAC3-5-MTHF complex with lower …
20254 citationsThe Effects of Folic Acid and 5-Methyltetrahydrofolate Supplementation on Folate Metabolism and One-Carbon Transfer Reactions in a Mouse Model
DJ Im - 2018 - search.proquest.com
… of FA and 5-MTHF supplementation on intracellular folate … as a prescription drug or nutritional supplement, and shows … Deplin® is prescribed at two doses of 7.5 mg or 15 mg tablets…
20183 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2021-02-25. DSLD Label ID: 242044. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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