Melatonin Controlled-Release®
Non-Nutrient / Non-BotanicalBrand: Douglas Laboratories
Net Contents
60 Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 45287 20032 2
Product Version
MEL-CR
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| Melatonin | 2 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 tablet 1 hour before bedtime as needed, or as directed by your healthcare professional.
Warnings & Precautions
Precautions re: Children
Warning: Not to be taken by individuals under the age of 18.
Precautions re: Pregnant or Nursing or Prescription Medications
If you are pregnant, nursing, taking any prescription medication (especially hormone replacement therapy), or have an autoimmune or depressive disorder consult a physician before using this product.
Precautions re: Children
KEEP OUT OF REACH OF CHILDREN.
Precautions re: All Other
Tamper resistant package, do not use if outer seal is missing.
Precautions re: All Other
Long-term use of melatonin has not been studied. Use of this product could cause hypothermia. Do not use before or while operating a motor vehicle or heavy machinery.
Storage
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
FDA Statements
FDA Statement of Identity
A Dietary Supplement
Other Label Statements
General: Product/Version Code
MEL-CR
Manufacturer & Distributor
Manufacturer
Douglas Laboratories
600 Boyce Road, Pittsburgh, PA, 15205, USA
1.800.245.4440
Market Reference
Douglas Laboratories Melatonin PR 60 Tablets
Cincinnati Health Institute4.6(68)$19.00Douglas Laboratories Melatonin 3mg 60 Tablets
Cincinnati Health Institute4.8(32)$16.00Douglas Laboratories Melatonin 1mg 60 Tablets
boulevardcompounding.com4.6(25)$14.00Douglas Laboratories Melatonin P.R. 3mg Prolonged-Release 60 Tablets
Supplement First4.5(63)$19.00Douglas Laboratories Melatonin 3 mg 60 Caps
Five Journeys4.8(32)$47.50Douglas Laboratories Melatonin 3mg 60 Capsules
Blue Sky Vitamin4.8(32)$16.00Natrol Melatonin 10mg Time Release Gummy 35Pc
Walmart4.4(153)$9.98Natrol Melatonin Time Release
Walgreens.com4.7(9700)$9.09
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Mississippi Discount Drugs
4.5 (27)Pharmacy
195 E Peace St #4519, Canton, MS 39046
Canton Discount Drugs
4.7 (39)Pharmacy
726 E Peace St, Canton, MS 39046
Square Nutrition
5.0 (10)Health food store
118 W Center St, Canton, MS 39046
GNC
3.7 (20)Vitamin & supplements store
175 Grandview Blvd Ste 420, Madison, MS 39110
Healthway Nutrition Center
4.8 (41)Health food store
398 US-51, Ridgeland, MS 39157
The Vitamin Shoppe
4.1 (118)Vitamin & supplements store
1220 E Northside Dr #400, Jackson, MS 39211
Skinny's Nutrition Studio
4.7 (35)Vitamin & supplements store
7048 Old Canton Rd, Ridgeland, MS 39157
MissisSIPPi Nutrition
4.8 (26)Tea store
340 Calhoun Station Pkwy Ste E, Madison, MS 39110
Research & Studies
Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements
DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
… health prompted by the pandemic and its lasting effects on mental health and sleep disturbances, melatonin … that a controlled-release oral melatonin supplement reduced asleep systolic …
2022215 citationsComparison of melatonin products against USP's nutritional supplements standards and other criteria
H Hahm, J Kujawa, L Augsburger - Journal of the American Pharmaceutical …, 1999 - Elsevier
… One controlled-release product released 90% of melatonin in … In vitro release profiles of the two controlled-release products … supplements should be a concern to consumers and health …
199950 citationsNighttime administration of high-dose, sustained-release melatonin does not decrease nocturnal blood pressure in African-American patients: results from a …
FF Rahbari-Oskoui, JL Abramson, AM Bruckman… - … therapies in medicine, 2019 - Elsevier
… Melatonin is an indole hormone secreted by the pineal gland and thought to reflect an … Italy and Israel showed a positive effect of controlled-release (CR) melatonin, at daily doses of 2–3 …
201918 citationsA randomized, double-blind, crossover study to investigate the pharmacokinetics of extended-release melatonin compared to immediate-release melatonin in healthy …
JG Mun, D Wang, DL Doerflein Fulk… - … Dietary Supplements, 2024 - Taylor & Francis
… Previous work investigated the pharmacokinetic properties of a surge-sustained release melatonin formulation, which combined immediate-release and controlled-release dosing. …
202422 citationsCytochrome P450-mediated drug metabolizing activity in the nasal mucosa
VS Dhamankar - 2013 - iro.uiowa.edu
… used to quantify the kinetic parameters for melatonin 6-hydroxylation. Results indicated that … melatonin metabolism, and the respiratory mucosa demonstrated the greatest melatonin 6-…
20134 citationsThe future of paediatric sleep medicine: a blueprint for advancing the field
O Bruni, P Corkum, RSC Horne, OS Ipsiroglu… - 2025 - pub.uni-bielefeld.de
… to a myriad of negative medical, mental health, functional, and … nia apart from a controlled-release melatonin for insomnia in … Second, the variability in access to melatonin for …
2025
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-07-25. DSLD Label ID: 10923. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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