Melatonin Controlled-Release

Non-Nutrient / Non-Botanical

Brand: Douglas Laboratories

Tablet or PillOff Market
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Net Contents

60 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 45287 20032 2

Product Version

Not specified

Suggested Use

Suggested Usage: As a dietary supplement; adults take 1 tablet 1 hour before bedtime as needed; or as directed by your healthcare professional.

Market Reference

$6.00 – $47.50· 40 listings
  • Douglas Laboratories Melatonin PR 60 Tablets

    Cincinnati Health Institute4.6(68)
    $19.00
  • Douglas Laboratories Melatonin 3mg 60 Tablets

    Cincinnati Health Institute4.8(32)
    $16.00
  • Douglas Laboratories Melatonin 1mg 60 Tablets

    boulevardcompounding.com4.6(25)
    $14.00
  • Douglas Laboratories Melatonin P.R. 3mg Prolonged-Release 60 Tablets

    Supplement First4.5(63)
    $19.00
  • Douglas Laboratories Melatonin 3 mg 60 Caps

    Five Journeys4.8(32)
    $47.50
  • Douglas Laboratories Melatonin 3mg 60 Capsules

    Blue Sky Vitamin4.8(32)
    $16.00
  • Natrol Melatonin 10mg Time Release Gummy 35Pc

    Walmart4.4(153)
    $9.98
  • Natrol Melatonin Time Release

    Walgreens.com4.7(9700)
    $9.09

Where to Buy Locally

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Research & Studies

  • Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

    DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com

    … health prompted by the pandemic and its lasting effects on mental health and sleep disturbances, melatonin … that a controlled-release oral melatonin supplement reduced asleep systolic …

    2022215 citations
  • Comparison of melatonin products against USP's nutritional supplements standards and other criteria

    H Hahm, J Kujawa, L Augsburger - Journal of the American Pharmaceutical …, 1999 - Elsevier

    … One controlled-release product released 90% of melatonin in … In vitro release profiles of the two controlled-release products … supplements should be a concern to consumers and health …

    199950 citations
  • Nighttime administration of high-dose, sustained-release melatonin does not decrease nocturnal blood pressure in African-American patients: results from a …

    FF Rahbari-Oskoui, JL Abramson, AM Bruckman… - … therapies in medicine, 2019 - Elsevier

    … Melatonin is an indole hormone secreted by the pineal gland and thought to reflect an … Italy and Israel showed a positive effect of controlled-release (CR) melatonin, at daily doses of 2–3 …

    201918 citations
  • A randomized, double-blind, crossover study to investigate the pharmacokinetics of extended-release melatonin compared to immediate-release melatonin in healthy …

    JG Mun, D Wang, DL Doerflein Fulk… - … Dietary Supplements, 2024 - Taylor & Francis

    … Previous work investigated the pharmacokinetic properties of a surge-sustained release melatonin formulation, which combined immediate-release and controlled-release dosing. …

    202422 citations
  • Cytochrome P450-mediated drug metabolizing activity in the nasal mucosa

    VS Dhamankar - 2013 - iro.uiowa.edu

    … used to quantify the kinetic parameters for melatonin 6-hydroxylation. Results indicated that … melatonin metabolism, and the respiratory mucosa demonstrated the greatest melatonin 6-…

    20134 citations
  • The future of paediatric sleep medicine: a blueprint for advancing the field

    O Bruni, P Corkum, RSC Horne, OS Ipsiroglu… - 2025 - pub.uni-bielefeld.de

    … to a myriad of negative medical, mental health, functional, and … nia apart from a controlled-release melatonin for insomnia in … Second, the variability in access to melatonin for …

    2025

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-07-25. DSLD Label ID: 10923. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.