Betaine Hydrochloride®

Non-Nutrient / Non-Botanical

Brand: Douglas Laboratories

CapsuleNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

250 Capsule(s)

Serving Size

1 Capsule(s)

Servings Per Container

250

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 45287 20026 1

Product Version

HC2

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Capsule(s) · 1 per day

IngredientAmount Per Serving
Betaine Hydrochloride648 mg

Not Present

Other Ingredients

CelluloseGelatinWaterMagnesium StearateSilica

Target Groups

Adult (18 - 50 Years)

Label Claims

All Other

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule just before or during each meal or as directed by your healthcare professional.

Warnings & Precautions

Precautions re: Children

KEEP OUT OF REACH OF CHILDREN.

Precautions re: All Other

Betaine Hydrochloride is a dietary supplement which adds hydrochloric acid to the stomach. Do not use if gastric hyperacidity or peptic ulcers are present. These capsules are intended to be taken whole, not pulled apart to be taken directly.

Precautions re: All Other

Tamper resistant package, do not use if outer seal is missing.

Storage

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

FDA Statements

FDA Statement of Identity

A Dietary Supplement

Other Label Statements

General: Product/Version Code

HC2

Seals/Symbols

amni(R) original formula

Manufacturer & Distributor

Manufacturer

Douglas Laboratories

600 Boyce Road, Pittsburgh, PA, 15205, USA

Market Reference

$11.69 – $53.50· 16 listings
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    Wholefood Guru4.9(22)
    $28.80
  • Betaine HCL

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    $21.05
  • Betaine Plus 90 Capsules

    Physicians Preference Vitamins
    $38.50
  • Thorne Betaine HCL & Pepsin 450 Capsules

    Thorne4.7(1200)
    $47.00
  • Pure Encapsulations Betaine HCl Pepsin 250ct

    Pine Street Clinic4.8(116)
    $53.50
  • Douglas Laboratories Douglas Labs B Complex with Metafolin

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    $28.99
  • Klaire Labs Betaine HCI Gastrointestinal + Detox Supplement

    boulevardcompounding.com5.0(3)
    $20.99
  • Enzyme Science Betaine HCL 120 Capsules

    Lifeworks Store
    $22.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • fithealthy.eu

    4.6 (54)

    Vitamin & supplements store

    Kārļa Mīlenbaha iela 5, Latgales priekšpilsēta, Rīga, LV-1050, Latvia

  • body Supplies

    4.1 (301)

    Vitamin & supplements store

    Donk 3a, 2991 LE Barendrecht, Netherlands

  • G&G Vitamins

    4.7 (36)

    Vitamin & supplements store

    Vitality House, 2-3 Imberhorne Way, East Grinstead RH19 1RL, United Kingdom

  • Supplementa Corporation B.V.

    4.9 (160)

    Vitamin & supplements store

    Papierbaan 50a, 9672 BH Winschoten, Netherlands

  • Bodystore.nl Supplements

    4.7 (105)

    Vitamin & supplements store

    Vogt 19, 6422 RK Heerlen, Netherlands

  • Vitamed

    5.0 (266)

    Vitamin & supplements store

    Ionos Dragoumi 45, Thessaloniki 546 30, Greece

  • Higher Nature

    4.2 (11)

    Vitamin & supplements store

    Higher Nature 10 Discovery Way, Horam, Heathfield TN21 0GE, United Kingdom

  • Amrita Nutrition UK

    4.6 (99)

    Wholesaler

    The Old Chapel, 8 Mortimer St, Sheffield City Centre, Sheffield S1 4SF, United Kingdom

Research & Studies

  • Metabolic effects of betaine: a randomized clinical trial of betaine supplementation in prediabetes

    AM Grizales, ME Patti, AP Lin… - The Journal of …, 2018 - academic.oup.com

    … betaine in modulating metabolic health, suggesting a potential therapeutic role in humans. High-fat diets reduce plasma betaine … in betaine metabolism, including betaine homocysteine …

    201862 citations
  • Betaine dietary supplementation: healthy aspects in human and animal nutrition

    G Buonaiuto, A Federiconi, CG Vecchiato, E Benini… - Antioxidants, 2025 - mdpi.com

    … synthesized endogenously from choline oxidation, betaine is widely used as a feed additive in the form of anhydrous betaine, betaine monophosphate, or betaine hydrochloride [184]. It …

    202525 citations
  • … and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy …

    W Atkinson, J Elmslie, M Lever… - … American journal of …, 2008 - academic.oup.com

    … Results: Dietary and supplementary betaine raised plasma betaine … the betaine content of the supplement and the high-betaine meal was not reflected by a change in plasma betaine …

    2008117 citations
  • Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males

    W Atkinson, S Slow, J Elmslie, M Lever… - Nutrition, Metabolism …, 2009 - Elsevier

    … not been established that dietary betaine has a … betaine-rich diet versus supplementation on plasma betaine, tHcy and lipid concentrations under fasting and PML conditions in healthy …

    200980 citations
  • The Complete Thyroid Health Guide: An Integrative Approach to Hormone Balance, Energy, and Everyday Wellness

    KW King - 2026 - books.google.com

    … It is available online through Douglas Laboratories at douglaslabs.com or on Amazon. On its … that betaine HCl supplementation should only be done under the guidance of a healthcare …

    2026
  • Betaine Protects Chronic Alcohol and ω‐3 PUFA‐Mediated Down‐Regulations of PON1 Gene, Serum PON1 and Homocysteine Thiolactonase Activities With …

    R Varatharajalu, M Garige, LC Leckey… - Alcoholism: Clinical …, 2010 - Wiley Online Library

    … Conclusions: Based on these results, we conclude that dietary betaine not only atheroprotective by restoring liver GSH that quenches free radicals, but also may alleviate liver injury by …

    201040 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2012-02-23. DSLD Label ID: 5373. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.