Brand: Doctor's Best

Tablet or PillNon-Nutrient/Non-BotanicalOff Market
Click to view full label

Net Contents

60 Enteric Coated Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

60

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 53950 00206 7

Product Version

Not Present

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Supplement Facts

Serving Size: 1 Tablet(s) · 1 per day

IngredientAmount Per Serving
S-Adenosyl Methionine200 mg
from 400 mg of SAM-e Tosylate Disulfate400 mg

Not Present

Other Ingredients

Cellulose GelMethacrylic Acid CopolymerCompritol 888ATOTalcTriethyl CitrateTitanium DioxideMagnesium StearateMannitolGlycerol PalmitostearateSilicaMedium Chain TriglyceridesSodium Starch GlycolateIron Oxide

Target Groups

VegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.

Precautions re: All Other

Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Precautions re: All Other

May cause gastrointestinal discomfort is a small percentage of people.

Storage

Storage

SAMe is sealed in blister packs for freshness and stability. Store product in a cool, dry place to ensure maximum quality.

Storage

Sealed in Blister Packs for Freshness & Convenience

Formulation

Formulation re: Does NOT Contain

The SAMe found in Doctor's Best SAMe 200mg is free from yeast, dairy, gluten, soy, wheat, and artificial flavoring.

Formula re: Contains

Our SAMe 200 contains 200mg of active SAMe in each tablet.

Formula re: Contains

Dietary Supplement with 200 mg Active S-Adenosyl Methionine Per Tablet

Formulation re: Vegetarian/Vegan

Suitable for Vegetarians

FDA Statements

FDA Statement of Identity

Dietary Supplement with 200 mg Active S-Adenosyl Methionine Per Tablet

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other Label Statements

General Statements: All Other Content

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

General Statements: All Other Content

Supplementing with SAMe The manufacturing process of SAMe yields two forms, the S,S and R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 200 is processed to yield the highest available percentage of the active pure S,S form on the market.

General Statements: All Other Content

CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS

General Statements: All Other Content

SAMe and Liver Function SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Brand IP Statement(s) re: (c), (TM), (SM)

Science-Based Nutrition(TM)

General Statements: All Other Content

Enhances Mood % Neural Function Promotes Joint Comfort & Mobility Supports Liver Health & Detoxification Pharmaceutical Grade Made in Italy

General Statements: All Other Content

SAMe and Joint Function SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

General Statements: All Other Content

SAMe and Neural Health SAMe-catalyzed methylation reactions promote he synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

General Statements: All Other Content

Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

Manufacturer & Distributor

Distributor

Doctor's Best, Inc.

1120 Calle Cordillera, Suite 101, San Clemente, CA, 92673

(800) 777-2474

Market Reference

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Where to Buy Locally

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Research & Studies

  • Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements

    KDR Setchell, NM Brown, P Desai… - The Journal of …, 2001 - academic.oup.com

    The pharmacokinetic behavior of naturally occurring isoflavones has been determined for the first time in healthy adults. We compared plasma kinetics of pure daidzein, genistein and …

    20011,290 citations
  • Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals

    RH Liu - The American journal of clinical nutrition, 2003 - academic.oup.com

    … has the same health benefit as the phytochemical present in whole food or a mixture of foods. It is now believed that dietary supplements do not have the same health benefits as a diet …

    20033,625 citations
  • Nutraceuticals to nourish the mind: targeted nutrition helps to strengthen and preserve cognitive function

    L Olivo - Nutraceuticals World, 2015 - go.gale.com

    … showed that 10 weeks of 200 mg twice daily supplementation of EVNol SupraBio softgels … for cognitive health. For example, the recently launched Doctor's Best PycnoBrain Complex …

    2015
  • Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center

    S Bent - Journal of general internal medicine, 2008 - Springer

    … supplement is that dietary supplements may not claim to “diagnose, cure, mitigate, treat, or prevent illness.”7 It is interesting to note that dietary supplement … a 15- to 200-fold variation in …

    20081,020 citations
  • Dietary supplements

    RJ Maughan, DS King, T Lea - Journal of sports sciences, 2004 - Taylor & Francis

    2004735 citations
  • Criteria and recommendations for vitamin C intake

    M Levine, SC Rumsey, R Daruwala, JB Park, Y Wang - Jama, 1999 - jamanetwork.com

    … health maintenance or disease outcome are conflicting. For example, vitamin C supplement … -fortified foods and beverages, a supplement containing 200 mg of vitamin C should suffice. …

    1999887 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-09-25. DSLD Label ID: 25569. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.