SAM-e 200 mg®
Non-Nutrient / Non-BotanicalBrand: Doctor's Best
Net Contents
60 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 53950 00206 7
Product Version
YDRB206-1
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 2 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl Methionine(SAM-e Tosylate Disulfate) | 200 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Adult Use: Take 1 tablet twice daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
Precautions re: All Other
Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe.
Precautions re: Pregnant or Nursing or Prescription Medications
Do not use if pregnant or nursing.
Precautions re: All Other
May cause gastrointestinal discomfort in a small percentage of people.
Formulation
Formula re: Contains
Our SAM-e 200 contains 200 mg of active Soloesse SAM-e in each tablet.
Formulation re: Vegetarian/Vegan
Vegan
Formulation re: Does NOT Contain
Gluten free / Soy free / Vegan
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
General Statements: All Other Content
SAM-e (S-Adenosyl Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.
General Statements: All Other Content
Doctor’s Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.
Brand IP Statement(s) re: (c), (TM), (SM)
Supplementing with SAM-e Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.
General Statements: All Other Content
SAM-e and Mood and Cognitive Function SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body’s antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.
General Statements: All Other Content
SAM-e and Joint Function In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.
General Statements: All Other Content
SAM-e and Liver Function SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.
Brand IP Statement(s) re: (c), (TM), (SM)
Soloesse is a registered trademark of Gnosis SpA.
Brand IP Statement(s) re: (c), (TM), (SM)
Science-Based Nutrition
Brand IP Statement(s) re: (c), (TM), (SM)
Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e available providing slow and targeted release for improved GI tolerance and absorption. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
General: Product/Version Code
YDRB206-1
General Statements: All Other Content
Helps enhance mood and neural function Helps promote joint comfort and mobility Helps support liver health and detoxification
Seals/Symbols
Vegan
General Statements: All Other Content
SAM-e is sealed in blister packs for freshness and stability.
Manufacturer & Distributor
Distributor
Doctor's Best, Inc.
(800) 777-2474
Market Reference
Doctor's Best SAM-e 200 mg Enteric Coated Tablets
iHerb4.7(665)$33.99SAMe 200
Pure Prescriptions$59.99SAM‐e 200 mg – Pharmaceutical‐Grade Mood & Joint Support Doctors Buy 3 Bottles 30 Save
Edom Laboratories$101.03Nature's Sunshine SAM-e 200 Mg 30 Tablets
Nature's Sunshine Products5.0(1)$75.05SAM-E 200mg Tablets (30 Tabs)
Zen Supplements$34.99Bestvite's SAMe 200mg 60 Tablets
Walmart - BESTVITE INC4.7(343)$24.99SuperSmart SAM-e 200mg
SuperSmart USA4.6(65)$62.00Swanson SAMe Dietary Supplements
Swanson Health Products4.6(221)$22.94
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Research & Studies
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …
202410 citationsAdemetionina-SAMe-Samyr
WDSAM Do - cfsitalia.it
… part of their daily nutritional health program, a daily dosage of 200 milligrams to 400 milligrams will be … SAM-e: This supplement should be avoided by any individual that is dealing with …
The SAM-e Solution: The Essential Guide to the Revolutionary Antidepression Supplement
D Mitchell - 2000 - books.google.com
… SAM-e levels are characteristic of many different medical conditions, which are discussed at length in this book. They also found that levels of SAM-e … blood levels of SAM-e than women, …
20004 citationsDietary supplement drug therapies for depression
RH Howland - … of psychosocial nursing and mental health …, 2012 - journals.healio.com
… Of the five products reviewed in this article, only omega-3 fatty acids and SAM-e seem to have enough supporting evidence for their effectiveness to warrant use. Nurses should be …
201219 citationsNutritional Supplements and PTSD.
CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com
… SAM-e also helps with healthy nerve conduction as well. It … of 200 mg twice daily, for the first day, then increase to 400 mg … day 10, and finally to the full dose of 400 mg four times daily.…
2018Complementary medicines
AW Fox - Principles and Practice of Pharmaceutical Medicine, 2002 - Wiley Online Library
… SAM-e recently became popular in North America, although it … SAM-e is also recommended for depression and anxiety, … mammalian liver, and thus swallowing 200 mg per day (a typical …
20021 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2017-12-22. DSLD Label ID: 81944. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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