SAM-e 200 mg®
Non-Nutrient / Non-BotanicalBrand: Doctor's Best
Functions
Net Contents
60 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
60
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 53950 00206 7
Product Version
YDRB206-3
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegetarian, Non-GMO, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Tablet(s) · 2 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| SAM-e(S-Adenosyl-L-Methionine Disulfate P-Toluenesulfonate) | 200 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Adult Use: Take 1 tablet twice daily between meals, or as recommended by a nutritionally informed physician. Do not chew or crush tablet.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
Precautions re: All Other
Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAM-e.
Precautions re: Pregnant or Nursing or Prescription Medications
Do not use if pregnant or nursing.
Precautions re: All Other
May cause gastrointestinal discomfort in a small percentage of people.
Storage
Storage
Store in a cool dry place.
Formulation
Formulation re: Other
Helps support mood and neural function Helps support joint comfort and mobility Helps support liver health and detoxification
Formulation re: Vegetarian/Vegan
Vegetarian
Formulation re: Does NOT Contain
Non-GMO Gluten free Soy free
Formula re: Contains
Doctor’s Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody. Supplementing with SAM-e Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.
Formulation re: Other
SAM-e and Mood and Cognitive Function SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body’s antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.
Formulation re: Other
SAM-e and Joint Function In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.
Formulation re: Other
SAM-e and Liver Function SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.
Formulation re: Other
Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our SAM-e 200 contains 200 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
FDA Statements
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Brand IP Statement(s) re: (c), (TM), (SM)
Science-Based Nutrition Doctor's Best
General Statements: All Other Content
SAM-e is sealed in blister packs for freshness and stability.
Manufacturer & Distributor
Distributor
Doctor's Best, Inc.
(800) 777-2474
Market Reference
Doctor's Best SAM-e 200 mg Enteric Coated Tablets
iHerb4.7(656)$33.99
Sam-e 200 200mg
Pure Prescriptions4.6(438)$55.99
SAMe 200mg 60 Tablets
Walmart - BESTVITE INC4.7(159)$24.99
SAM-E 200mg Tablets (30 Tabs)
McGuff Medical Products$22.75
Nature's Sunshine SAM-e 200 Mg 30 Tablets
Nature's Sunshine Products5.0(1)$75.05
SAM-E 200 mg 60 Capsules
Physicians Preference Vitamins$84.50
Doctor's Best 120 Vcaps
Shipman's Pharmacy3.7(3)$24.10
Vitacost Synergy SAM-e Enteric Coated Tablets
Target4.7(109)$19.99
Where to Buy Locally
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Showing representative supplement & health retailers — search above for stores in your area.
GNC
4.8 (387)Vitamin & supplements store
800 E Dimond Blvd Ste 117, Anchorage, AK 99515
Research & Studies
Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity
RP Brown, PL GERBARG - Journal of Psychiatric Practice, 2001 - ovid.com
… In one double-blind crossover study, 8 out of 21 patients with Parkinson’s disease showed significant improvement in depression when given SAM-e (800 mg po plus 200 mg IM per day…
200159 citationsDietary supplement drug therapies for depression
RH Howland - … of psychosocial nursing and mental health …, 2012 - journals.healio.com
… Of the five products reviewed in this article, only omega-3 fatty acids and SAM-e seem to have enough supporting evidence for their effectiveness to warrant use. Nurses should be …
201219 citationsNutritional Supplements and PTSD.
CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com
… SAM-e also helps with healthy nerve conduction as well. It … of 200 mg twice daily, for the first day, then increase to 400 mg … day 10, and finally to the full dose of 400 mg four times daily.…
2018Complementary medicines
AW Fox - Principles and Practice of Pharmaceutical Medicine, 2002 - Wiley Online Library
… SAM-e recently became popular in North America, although it … SAM-e is also recommended for depression and anxiety, … mammalian liver, and thus swallowing 200 mg per day (a typical …
20021 citationsAnxiety, depression, and insomnia
MM Larzelere, P Wiseman - Primary Care: Clinics in …, 2002 - primarycare.theclinics.com
… mg twice daily, but therapeutic doses and toxicities are not clearly defined. Caution should be used in combining SAM-e … investigations of amitriptyline (150–200 mg/day) and electro-…
200275 citationsSAMe: A dietary tonic for mind and body? Is it the long awaited wonder cure?
S Armin - Nutrition Bytes, 2000 - escholarship.org
… information on the supplement, have already been developed. "Same- Support", a web site … (therapeutic effect at low doses, 100-200 mg daily, with minimal side effects) for treatment of …
2000
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-06-16. DSLD Label ID: 269492. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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