Double-Strength SAMe 400®
Non-Nutrient / Non-BotanicalBrand: Doctor's Best
Net Contents
30 Enteric Coated Tablet(s)
Serving Size
1 Tablet(s)
Servings Per Container
30
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
7 53950 00151 0
Product Version
Not Present
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Supplement Facts
Serving Size: 1 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosyl Methionine | 400 mg | — |
| from 800 mg of SAM-e tosylate disulfate | 800 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Suggested Adult Use: Take 1 tablet daily away from food, or as directed by a health care professional. Do not shew or crush tablet.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.
Precautions re: All Other
Individuals diagnosed wit bipolar disease or manic depression should avoid supplementing with SAMe.
Precautions re: Pregnant or Nursing or Prescription Medications
Do not use if pregnant or nursing.
Precautions re: All Other
May cause gastrointestinal discomfort is a small percentage of people.
Storage
Storage
Double-Strength SAMe is sealed in blister packs for freshness and stability. Store product in a cool, dry place to ensure maximum quality.
Storage
Sealed in Blister Packs for Freshness & Convenience
Formulation
Formula re: Contains
Our Double-Strength SAMe 400 contains 400mg of active SAMe in each tablet.
Formula re: Contains
Dietary Supplement with 400mg Active S-Adenosyl Methionine Per Tablet
Formulation re: Does NOT Contain
The SAMe found in Doctor's Best SAMe 400mg is free from yeast, dairy, gluten, soy, wheat, and artificial flavoring.
Formulation re: Vegetarian/Vegan
Suitable for Vegetarians
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement with 400mg Active S-Adenosyl Methionine Per Tablet
Other Label Statements
General Statements: All Other Content
S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Mehtylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.
General Statements: All Other Content
Supplementing with SAMe The manufacturing process of SAMe yields two forms, the S,S and R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.
General Statements: All Other Content
SAMe and Joint Function SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential somponents of connective tissue. Clinical studies show and ability of SAMe to enhance mobility and movement, and promote joint comfort.
General Statements: All Other Content
SAMe and Neural Health SAMe-catalyzed methylation reactions promote he symthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidycholine, supporting cognitive function.
General Statements: All Other Content
SAMe and Liver Function SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.
General Statements: All Other Content
Doctor's Best utilizes only the highest quality Italian SAMe available on e market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.
Brand IP Statement(s) re: (c), (TM), (SM)
Science-Based Nutrition(TM)
General Statements: All Other Content
Enhances Mood & Neural Function Promotes Joint Comfort & Mobility Supports Liver Health & Detoxification Pharmaceutical Grade Made in Italy
General Statements: All Other Content
CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS
Manufacturer & Distributor
Distributor
Doctor's Best, Inc.
1120 Calle Cordillera, Suite 101, San Clemente, CA, 92673
(800) 777-2474
Market Reference
Doctor's Best SAMe 400 mg Double Strength Enteric Coated Tablets
iHerb4.7(771)$48.99
Doctor's Best SAM-e 400 mg Enteric Coated Tablets
Pakuranga Pharmacy4.0(1)$82.53
Doctor's Best Glucosamine Chondroitin MSM
Walmart - iHerb4.8(22000)$35.30
Doctor's Best Fully Active Folate 400
Target4.8(3500)$13.99
Doctor’s Best High Absorption Iron
Clark’s Markets$13.29Lowest
Doctor's Best Synergistic Glucosamine/MSM Formula
Mothers Market & Kitchen4.8(2000)$31.29
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
The Vitamin Shoppe
4.4 (144)Vitamin & supplements store
31753 Woodward Ave, Royal Oak, MI 48073
GNC
4.2 (39)Vitamin & supplements store
29850 Southfield Rd, Southfield, MI 48076
CVS
3.5 (100)Vitamin & supplements store
18130 W 10 Mile Rd, Southfield, MI 48075
Dynamite Wholesale Nutrition
5.0 (51)Vitamin & supplements store
21819 John R Rd, Hazel Park, MI 48030
Elite Megastore
4.2 (13)Vitamin & supplements store
34769 Dequindre Rd, Troy, MI 48083
Project-Enhanced Fitness
5.0 (11)Vitamin & supplements store
2715 Puritan Ave, Detroit, MI 48238
GNC
4.5 (34)Vitamin & supplements store
28300 Telegraph Rd, Southfield, MI 48034
The Vitamin Shoppe
4.6 (103)Vitamin & supplements store
30730 Orchard Lake Rd, Farmington Hills, MI 48334
Research & Studies
Home/Library/Brain Health/The Best Nutrients For Building Brain Connections By Dr. Parris Kidd
P Kidd - needs.com
… health benefits in clinical studies, and the Doctor's Best team has developed a number of them into brain supplements… Doctor's Best SAMe and Double Strength SAMe are identical to …
Home/Articles/Brain Health/The Best Nutrients For Building Brain Connections By Dr. Parris Kidd
P Kidd
Botanical-drug interactions: a scientific perspective
MLT Vieira, SM Huang - Planta medica, 2012 - thieme-connect.com
… Double-strength: one can of GFJ frozen concentrate diluted with one can of water. * § Single… study in healthy volunteers, garlic supplements (using a product from the same manufacturer …
2012112 citationsA comprehensive review of post-market clinical studies performed in adults with an Asian probiotic formulation
TA Tompkins, X Xu, J Ahmarani - Beneficial microbes, 2009 - brill.com
… , respectively (DS referring to ‘double strength’). In Asia these … applications for probiotic supplements, expected outcomes, … attempt to assign a potential health benefit to cirrhotic liver …
200956 citationsreduce relapse MULTIPLE SCLEROSIS
L McNamara - drladdvip.com
… medical disclaimer below, and consult with your personal physician prior to taking supplements … Taking 2 tablets of a double-strength vision support supplement, provides an additional …
Essentials of herb-drug interactions in the elderly with cardiovascular disease
S Sultan, M Viqar, R Ali, AJ Tajik… - Journal of Patient …, 2015 - institutionalrepository.aah.org
… supplements do not disclose such to health care professionals.Thus, the risk for potential interactions between supplements … was used (eg high dose, double strength) or as a “moderate …
201518 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2013-09-25. DSLD Label ID: 25574. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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