SAM-e 200 mg®
Non-Nutrient / Non-BotanicalBrand: DC
Functions
Net Contents
60 Enteric Coated Tablet(s)
Serving Size
2 Tablet(s)
Servings Per Container
30
Supplement Form
Tablet or Pill
Bar Code (UPC/SKU)
Not specified
Product Version
#222 Rev. #03
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Vegan, Vegetarian, Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Contains
- Milk
- Egg
- Fish
- Shellfish
- Tree Nuts
- Peanut
- Soy
Free From
- Wheat
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 2 Tablet(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| S-Adenosylmethionine | 400 mg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions: For adults, we recommend taking two (2) tablets daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.
Warnings & Precautions
Precautions re: Pregnant or Nursing or Prescription Medications
Caution: You should consult your physician before using SAM-e if you are taking MAO Inhibitors.
Precautions re: Children
Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
Precautions re: Pregnant or Nursing or Prescription Medications
Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.
Precautions re: All Other
Individuals affected by bipolar (manic) depression should not take this product. Discontinue use and consult your physician if gastrointestinal discomfort occurs.
Precautions re: All Other
Tamper Evident: Do not use if imprinted foil seal under cap is broken or missing.
Precautions re: Children
Keep out of reach of children.
Storage
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
Formulation
Formula re: Contains
All living things contain SAM-e (S-adenosylmethionine). The body makes SAM-e from the amino acid methionine. However, you may not be able to obtain sufficient methionine levels simply by ingesting food. In addition, because of age of other factors, levels of SAM-e can fluctuate or decline. Supplementation with SAM-e is the easiest way to increase intake. SAM-e is involved in over 35 biochemical reactions involving enzymatic transmethylation. The methylation process is the mechanism by which the body rids itself of potentially damaging compounds, synthesizes neurotransmitters, makes components of cartilage, regulates enzyme activity within the cell and maintains the flexibility of cell membranes. Science has been looking into this remarkable supplement and time after time clinical studies have drawn the same conclusions, SAM-e: Promotes healthy joint function and comfort - Boosts mood and emotional well-being. SAM-e is a revolutionary supplement. Because of its popularity and use, it has received widespread exposure in the press. Information has appeared in newspapers, magazine, on the internet, or simply through word of mouth. Whether you're a first time SAM-e user, or have been a fan for years, you probably have some questions. Please see enclosed insert for more information. A note about our enteric coating: SAM-e is enterically coated so that you receive optimal absorption. The enteric coating ensures that the breakdown of SAM-e occurs in the small intestine. Clinical trials indicate that absorption is more efficient in the small intestine rather than in the stomach. In addition, the enteric coating is designed to protect SAM-e from moisture. The lack of an enteric coating should not be harmful to the stomach, and there have been no reported cases tot his effect. However, the enteric coating serves as a protective barrier so that SAM-e can be absorbed where it can provide you with the greatest benefits.
Formulation re: Other
Conforms to USP <2091> for weight. Meets USP <2040> disintegration.
Formulation re: Does NOT Contain
Gluten free
Formula re: Contains
S-adenosylmethionine 200 mg
Formulation re: Other
Promotes healthy joint function and comfort Boosts mood and emotional well-being Supports healthy liver function
Formulation re: Other
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Formulation re: Vegetarian/Vegan
Suitable for vegetarians/vegans.
Formulation re: Does NOT Contain
Contains no wheat, soy, dairy, egg, fish/shellfish, peanuts/tree nuts.
Formulation re: Other
Made in USA
FDA Statements
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Other Label Statements
Seals/Symbols
Quali Pure
General Statements: All Other Content
SAM-e was discovered in Italy in 1952 and has been one of Europe's best kept secrets for years. Through extensive testing, SAM-e has been shown to be well tolerated by most. But, perhaps the best news is that SAM-e has been found to be a safe nontoxic supplement for nearly everyone in levels of up to 1,600 mg per day.
Manufacturer & Distributor
Distributor
Dee Cee Laboratories, Inc.
304 Dee Cee Ct., White House, TN, 37188
Market Reference
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SAM-e 200 mg 30 Tablets
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Vitacost Synergy SAM-e Enteric Coated Tablets
iHerb4.7(109)$15.99Lowest
SuperSmart SAM-e 200mg
SuperSmart USA4.6(63)$62.00
Jarrow Formulas SAM-e 200 Tablets
Walsh Natural Health4.6(438)$18.49
SAMe 200mg 60 Tablets
Bestvite4.7(159)$20.99
NOW Foods SAMe 200 mg 60 Veg Capsules
Dr. Judy Morgan's Naturally Healthy Pets4.6(14)$39.99
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Research & Studies
S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review
KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com
… depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …
202410 citationsS-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS
RA Shippy, D Mendez, K Jones, I Cergnul, SE Karpiak - BMC psychiatry, 2004 - Springer
… symptoms, (g) reversible medical pathology that is thought to … at 200 mg of SAM-e twice a day with daily supplementation … dose of SAM-e was individually adjusted up to 800 mg, twice …
200473 citationsDietary supplement drug therapies for depression
RH Howland - … of psychosocial nursing and mental health …, 2012 - journals.healio.com
… Of the five products reviewed in this article, only omega-3 fatty acids and SAM-e seem to have enough supporting evidence for their effectiveness to warrant use. Nurses should be …
201219 citationsDietary supplements: Evaluation and application in clinical practice
CA Thomson, T Newton - Topics in Clinical Nutrition, 2005 - journals.lww.com
… health status, by legal definition, dietary supplementation is … /d), melatonin (2.5 mg/d), and SAM-e (200 mg/d). She reports … Likewise, SAM-e was shown to be effective in the treatment …
20059 citationsEvidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com
… supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-l-methionine (SAM-e)… and colleagues32 reported 200 mg/d of intravenous SAM-e to be …
2009178 citationsNutritional Supplements and PTSD.
CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com
… SAM-e also helps with healthy nerve conduction as well. It … of 200 mg twice daily, for the first day, then increase to 400 mg … day 10, and finally to the full dose of 400 mg four times daily.…
2018
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-02-23. DSLD Label ID: 266491. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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