Brand: DC

Tablet or PillOn Market
Click to view full label

Net Contents

30 Enteric Coated Tablet(s)

Serving Size

2 Tablet(s)

Servings Per Container

Not specified

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

Not specified

Product Version

Not specified

Suggested Use

Directions: For adults; we recommend taking two (2) tablets daily; preferably on an empty stomach. In order to obtain maximum benefits; SAM-e should be taken at least 30 minutes prior to a meal.

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

Research & Studies

  • S-Adenosylmethionine (SAMe) for Central Nervous System Health: A Systematic Review

    KER Baden, H McClain, E Craig, N Gibson, JA Draime… - Nutrients, 2024 - mdpi.com

    … depressive symptoms were seen ranging from 200 mg to 3200 mg. Many studies started at … doses starting at 200 mg to 800 mg for mild–moderate depression and 800 mg daily in one to …

    202410 citations
  • S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS

    RA Shippy, D Mendez, K Jones, I Cergnul, SE Karpiak - BMC psychiatry, 2004 - Springer

    … symptoms, (g) reversible medical pathology that is thought to … at 200 mg of SAM-e twice a day with daily supplementation … dose of SAM-e was individually adjusted up to 800 mg, twice …

    200473 citations
  • Dietary supplement drug therapies for depression

    RH Howland - … of psychosocial nursing and mental health …, 2012 - journals.healio.com

    … Of the five products reviewed in this article, only omega-3 fatty acids and SAM-e seem to have enough supporting evidence for their effectiveness to warrant use. Nurses should be …

    201219 citations
  • Dietary supplements: Evaluation and application in clinical practice

    CA Thomson, T Newton - Topics in Clinical Nutrition, 2005 - journals.lww.com

    … health status, by legal definition, dietary supplementation is … /d), melatonin (2.5 mg/d), and SAM-e (200 mg/d). She reports … Likewise, SAM-e was shown to be effective in the treatment …

    20059 citations
  • Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.

    GI Papakostas - Journal of Clinical Psychiatry, 2009 - psychiatrist.com

    … supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-l-methionine (SAM-e)… and colleagues32 reported 200 mg/d of intravenous SAM-e to be …

    2009178 citations
  • Nutritional Supplements and PTSD.

    CD Townsend - … Perspectives: Journal of the Council on …, 2018 - search.ebscohost.com

    … SAM-e also helps with healthy nerve conduction as well. It … of 200 mg twice daily, for the first day, then increase to 400 mg … day 10, and finally to the full dose of 400 mg four times daily.…

    2018

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-05-19. DSLD Label ID: 266484. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.