5-HTP

Suggested Use

Directions: As a dietary supplement; start with a low dose of 1 capsule taken with a meal. Increase the dose slowly (every 3-5 days) up to a maximum of 4 capsules taken daily. Total daily intake should be divided into two or more doses; with no more than 2 capsules per dose.

• 

  Nutricost 5-HTP Capsules

  Walmart4.7(2400)

  $5.48
• 

  Walgreens 5-HTP 100 mg Capsules

  Walgreens.com4.7(3)

  $13.99
• 

  CVS Health 5-HTP Capsules 30 ct

  CVS Pharmacy4.0(58)

  $15.69
• 

  Irwin Naturals Double Potency 5-HTP Extra Softgels

  Irwin Naturals4.8(167)

  $19.99
• 

  Nature's Bounty 5-HTP 100 Mg Capsules

  iHerb4.5(92)

  $14.36
• 

  Thorne Research 5-Hydroxytryptophan 90 Capsules

  ClearSpring Pharmacy4.7(673)

  $39.00
• 

  Jarrow Formulas 5-HTP 100 mg 60 Capsules

  Whole Foods Market4.7(253)

  $31.49
• 

  Natrol 5 HTP Time Release

  Walgreens.com4.6(948)

  $17.49

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

• The Vitamin Shoppe

  4.6 (175)

  Vitamin & supplements store

  1234 U.S. Hwy 31 N, Greenwood, IN 46142

  Directions(317) 881-5358

• The Supplement Store

  4.8 (35)

  Vitamin & supplements store

  7747 Shelby St, Indianapolis, IN 46227

  Directions(317) 361-4563

• Health Spot (Greenwood)

  4.8 (39)

  Vitamin & supplements store

  914 U.S. Hwy 31 N, Greenwood, IN 46142

  Directions(317) 888-7996

• Peptides & Suplements

  5.0 (3)

  Vitamin & supplements store

  711 S Bosart Ave, Indianapolis, IN 46203

  Directions

• Power Up Supplements and Smoothies

  4.8 (98)

  Health food store

  5329 E Thompson Rd, Indianapolis, IN 46237

  Directions(317) 763-0000

• Cutting Edge Nutrition

  4.9 (134)

  Vitamin & supplements store

  8282 Center Run Dr, Indianapolis, IN 46250

  Directions(317) 585-0605

• GNC

  3.5 (63)

  Vitamin & supplements store

  5370 E Thompson Rd, Indianapolis, IN 46237

  Directions(317) 536-0910

• The Vitamin Shoppe

  4.5 (124)

  Vitamin & supplements store

  10110 E Washington St, Indianapolis, IN 46229

  Directions(317) 897-3913

• 5-Hydroxytryptophan (5-HTP): Natural occurrence, analysis, biosynthesis, biotechnology, physiology and toxicology

  ME Maffei - International journal of molecular sciences, 2020 - mdpi.com

  … This review describes the natural sources of 5-HTP, which represent the raw material from which 5-HTP may be extracted and purified for its use in drugs and dietary supplements, as …

  2020319 citations

• Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight …

  M Rondanelli, A Opizzi, M Faliva, M Bucci… - Eating and Weight …, 2012 - Springer

  … Previous observations have shown that oral administration of 5-HTP is useful for losing … the efficacy of a dietary supplement with natural plant extracts rich in 5-HTP, administered via the …

  201256 citations

• Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis

  F Javelle, A Lampit, W Bloch, P Häussermann… - … reviews, 2020 - academic.oup.com

  … As will be discussed below, 5-HTP may have some benefits compared to TRP. This meta-… Reviews and Meta-Analysis) guidelines, aimed to evaluate the findings concerning 5-HTP as a …

  202062 citations

• Edible mushrooms as a potential component of dietary interventions for major depressive disorder

  A Fijałkowska, K Jędrejko, K Sułkowska-Ziaja, M Ziaja… - Foods, 2022 - mdpi.com

  … Similarly, the results of meta-analyses of studies examining the therapeutic potential of tryptophan [46] or 5-HTP [53] in MDD are inconclusive, with 5-HTP found to be a more promising …

  202238 citations

• The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial

  S Li, CN Sutanto, X Xia, JE Kim - Nutrients, 2025 - mdpi.com

  … body composition management and mental health regulation [21,23… healthy and had not previously taken 5-HTP supplementation, 100 mg was selected to balance the potential benefits …

  20254 citations

• The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT

  C Evans, V Mekhail, J Curtis, P Czartoryski… - … Dietary Supplements, 2023 - Taylor & Francis

  … This investigation discovered that 5-HTP intake influences areas of the brain related to … fatty foods compared to the 5-HTP group. This study suggests that 5-HTP intake can influence …

  202311 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-06-16. DSLD Label ID: 266891. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.