Net Contents
100 Capsule(s)
Serving Size
1 Capsule(s)
Servings Per Container
100
Supplement Form
Capsule
Bar Code (UPC/SKU)
6 96859 13177 6
Product Version
Not Present
Label Analysis
Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.
Single-ingredient formula listed in Supplement Facts.
Every active ingredient discloses a specific amount per serving.
Label states: Gluten-Free.
This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.
Allergen Guide
Free From
- Milk
- Soy
- Gluten
Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.
Supplement Facts
Serving Size: 1 Capsule(s) · 1 per day
| Ingredient | Amount Per Serving | |
|---|---|---|
| L-5-Methyltetrahydrofolate(Calcium Salt) | 1000 mcg | — |
Not Present
Other Ingredients
Target Groups
Label Claims
Directions & Suggested Use
Suggested/Recommended/Usage/Directions
Directions Take one capsule daily with food or as directed by a physician.
Formulation
Formula re: Contains
This scientifically-designed dietary supplement contains 5-methyltetrahydrofolate, the most biologically active form of the B vitamin folic acid. This metabolic form of folate provides superior absorption.
Formulation re: Does NOT Contain
Contains: No soy, yeast, dairy, sugar, gluten, artificial colors, flavors or preservatives. Gluten free, casein free
FDA Statements
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Other Label Statements
General Statements: All Other Content
Ecological Formulas
Brand IP Statement(s) re: (c), (TM), (SM)
Cardiovascular Research Ltd.
Manufacturer & Distributor
Distributor
Cardiovascular Research, Ltd.
1061-B Shary Circle, Concord, CA, 94518
Market Reference
Carlyle Opti-Folate L Methylfolate 1000mcg
Target4.5(13)$16.99L-Methylfolate 1000 mcg
Professional Supplement Center5.0(17)$16.99Methyl Folate 1000mcg
Horbäach4.8(12)$13.99Triquetra Health L-Methylfolate Plus Methyl-B12
Triquetra Health4.8(575)$110.99Methyl Folate 1000 mcg 100 caps
Curated Wellness4.8(1400)$33.99Now Supplements Methyl Folate 1,000 mcg Metabolically Active Folate
Walmart - Highland Health Foods4.8(4800)$26.92Double Wood Supplements Methylfolate 1,000mcg Capsules Vegan and Non-GMO
Double Wood Supplements4.9(10)$19.95L-Methylfolate 1000mcg 200 Capsules
Discount Health Products$26.34
Where to Buy Locally
Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.
Showing representative supplement & health retailers — search above for stores in your area.
Earth Heart
4.7 (61)Vitamin & supplements store
4573 US-221 N, Marion, NC 28752
The Nutrition Store - Spartanburg
5.0 (324)Vitamin & supplements store
1398 Boiling Springs Rd E, Spartanburg, SC 29303
The Vitamin Shoppe
4.3 (135)Vitamin & supplements store
148 Tunnel Rd, Asheville, NC 28805
Supreme Nutrition Greenville
5.0 (227)Vitamin & supplements store
1143 Woodruff Rd Ste A-2, Greenville, SC 29607
GNC
3.7 (28)Vitamin & supplements store
142 Morganton Heights Blvd A, Morganton, NC 28655
Dr. Herb's Natural Food Store
4.7 (120)Vitamin & supplements store
1920 U.S. Hwy 70 SW, Hickory, NC 28602
The Vitamin Shoppe
4.6 (141)Vitamin & supplements store
5790 Wade Hampton Blvd Ste a, Taylors, SC 29687
GNC
4.5 (21)Vitamin & supplements store
146 Plaza Dr, Forest City, NC 28043
Research & Studies
Vitamins, Vascular Health and Disease
G Ayoub - Nutrients, 2025 - mdpi.com
… In this paper, we use the term methylfolate to refer to the active form L-methylfolate … demonstrates that folate can enhance vascular reactivity and may reduce cardiovascular disease (…
202510 citationsThe HCG Institute> Blog> Vitamins> 5 Remarkable Benefits of Methylfolate (Vitamin B9)
C Maghinay, M Smith - thehcginstitute.com
… diseases, including cardiovascular disease, neurodegenerative … Methylfolate, also known as L-methylfolate or 5-MTHF, is the … overall cellular health, promoting cardiovascular health by …
Best Of L-Methylfolate: Uses, Effects, Dosage & Interactions
C Maghinay, M Smith - thehcginstitute.com
… , a common dosage is between 400 mcg to 1,000 mcg (1 mg) … as supporting mental health, cardiovascular function, and … thus reducing the risk of heart disease and stroke. Moreover, …
11 Evidence-Based Methylfolate Benefits (2026 Guide)
HDM Work - biochron.net
… health, cardiovascular system, and overall wellness, all backed by clinical research from 16 peer-reviewed studies… of 9 studies (N=6,707) found adjunctive L-methylfolate improved …
Effect of Methylfolate, Pyridoxal-5′-Phosphate, and Methylcobalamin (SolowaysTM) Supplementation on Homocysteine and Low-Density Lipoprotein …
E Pokushalov, A Ponomarenko, S Bayramova… - Nutrients, 2024 - mdpi.com
… ) and cardiovascular disease (CVD), this study evaluates the effect of B vitamin supplements (… the interaction between genetics, micronutrient metabolism, and cardiovascular health. Our …
202413 citationsGood, better, best: clinical scenarios for the use of L-methylfolate in patients with MDD
R Jain, S Manning, AJ Cutler - CNS spectrums, 2020 - cambridge.org
… Among these is L-methylfolate, a medical food that is thought to enhance synthesis of … Studies have demonstrated an increased risk of cardiovascular disease and cardiacrelated …
202038 citations
Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2023-12-14. DSLD Label ID: 304400. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.
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