St. John's Wort Extract®

Botanicals & Herbs

Brand: 21st Century

CapsuleBotanicalOn Market
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Net Contents

60 Vegetarian Capsule(s)

Serving Size

1 Vegetarian Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 40985 21312 4

Product Version

500118-0217N

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Vegetarian Capsule(s) · 2 per day

IngredientAmount Per Serving
St. John's Wort extract(Hypericum perforatum)300 mg

Not Present

Other Ingredients

CelluloseRice BranOat FiberMaltodextrinContains Less Than 2% of

Target Groups

VegetarianAdult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a herbal supplement, adults take one (1) capsule with any meal, twice daily or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Precautions re: All Other

Do not exceed recommended dosage.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Precautions re: All Other

Stop use and contact a physician if adverse reactions occur.

Precautions re: Children

Keep out of reach of children.

Precautions re: All Other

Do not use if product appears to be tampered with or seal is broken.

Storage

Storage

Store at room temperature.

Formulation

Formulation re: Does NOT Contain

No added sugar, salt, yeast, preservatives or artificial flavors.

Formulation re: Vegetarian/Vegan

100% Vegetarian.

Formulation re: Other

Standardized Mood & mental outlook support

Formulation re: Does NOT Contain

Gluten free

Formula re: Contains

St. John's Wort Extract (Hypericum perforatum) is a perennial plant found in North America containing hypericin and used for many years as a calming herb to support mood and mental outlook.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Other Label Statements

General Statements: All Other Content

Individual results may vary.

Seals/Symbols

Guaranteed quality Laboratory tested

General Statements: All Other Content

500118-0916N

Manufacturer & Distributor

Manufacturer

21st Century HealthCare, Inc.

2119 S. Wilson St., Tempe, AZ, 85282, USA

Market Reference

$5.99 – $1540.00· 40 listings
  • 21st Century St. John's Wort Extract

    biomall.bg
    $11.47
  • Spring Valley St. John's Herbal Supplement Capsules

    Walmart4.6(120)
    $11.82
  • Nature's Bounty St. John's Wort 300 mg

    Vitacost.com4.6(194)
    $11.88
  • Mountain Rose Herbs St John's Wort Extract Organic

    Mountain Rose Herbs4.9(8)
    $12.75
  • GNC Herbal Plus St. John's Wort Extract 300Mg

    GNC4.4(36)
    $29.99
  • Healths Harmony St John's Wort Extract

    Macy's4.7(246)
    $21.97
  • Nature's Answer St John's Wort Young Flowering Tops

    USA Apteka4.6(23)
    $8.99
  • Swanson Vitamins St. John's Wort Extract

    Swanson Health Products4.7(282)
    $10.61

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

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  • Nutristore

    4.9 (20)

    Vitamin & supplements store

    Via Lincoln, 128, 90123 Palermo PA

  • Fitness e Nutrizione - Presso Atlantis Fitness Center

    4.9 (359)

    Sports nutrition store

    Presso Atlantis Fitness Center, Via Brigata Aosta, 23, 90142 Palermo PA

  • Body Store

    5.0 (16)

    Vitamin & supplements store

    Via Pietro Spica, 12, 90124 Palermo PA

  • Body Store Toselli

    4.8 (163)

    Health food store

    Via Maggiore Pietro Toselli, 112, 90143 Palermo PA

  • 3G Nutrition Store

    5.0 (64)

    Sports nutrition store

    Via Mico Geraci, 17, 90125 Palermo PA

Research & Studies

  • Over-the-counter psychotropics: a review of melatonin, St John's wort, valerian, and kava-kava

    E Heiligenstein, G Guenther - Journal of American College Health, 1998 - Taylor & Francis

    … Our recent search for entries about St John’s wort, an herbal used to treat depression, found … St John’s wort (Hypericum pe&ratum) is a perennial herb that has been used for centuries to …

    199863 citations
  • History and therapeutic properties of Hypericum perforatum from antiquity until today

    CI Istikoglou, V Mavreas, G Geroulanos - Psychiatriki, 2010 - betamedarts.gr

    … of the time remarked that Saint John’s Wort was an excellent drug … for centuries, the benefits from Saint John’s Wort have been … For instance, the effectiveness of Saint John’s Wort for the …

    201068 citations
  • Polyphenol and Flavonoid Content and Antioxidant Activity of Hypericum perforatum L. (St. John's Wort) Extracts for Potential Pharmaceutical and Cosmetic …

    E Błońska-Sikora, A Zielińska, N Dobros… - Applied Sciences, 2025 - mdpi.com

    … John’s wort (Hypericum perforatum) has been used for centuries in traditional medicine owing to its high content of various bioactive metabolites and wide geographic occurrence. …

    202515 citations
  • Safety of St. John's Wort extract compared to synthetic antidepressants

    V Schulz - Phytomedicine, 2006 - Elsevier

    … In contrast, the interaction between St. John's Wort and digoxin hardly represents a serious therapeutic risk. According to a recently published study with 96 subjects, the maximal …

    2006145 citations
  • Herbal medicines today and the roots of modern pharmacology

    P Goldman - Annals of internal medicine, 2001 - acpjournals.org

    … of 147 patients that compared two St. John's wort extracts of equal hypericin content with … preparations that were reminiscent of digitalis formulations at the beginning of the 20th century. …

    2001397 citations
  • Medical attributes of St. John's wort (Hypericum perforatum)

    KM Klemow, E Bilbow, D Grasso, K Jones… - Oxidative Stress and …, 2004 - taylorfrancis.com

    … John’s wort has been used as an herbal remedy to treat a variety of internal and external … Sales of products made from St. John’s wort presently exceed several billion dollars each …

    2004234 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2022-01-22. DSLD Label ID: 258594. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.