St. John's Wort Extract®

Botanicals & Herbs

Brand: 21st Century

CapsuleBotanicalOn Market
Click to view full label

Net Contents

60 Vegetarian Capsule(s)

Serving Size

1 Vegetarian Capsule(s)

Servings Per Container

Not specified

Supplement Form

Capsule

Bar Code (UPC/SKU)

7 40985 21312 4

Product Version

500118-0217N

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2Dietary Attributes

Label states: Vegetarian, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Vegetarian Capsule(s) · 2 per day

IngredientAmount Per Serving
St. John's Wort extract(Hypericum perforatum)300 mg

Not Present

Other Ingredients

CelluloseRice BranOat FiberMaltodextrinContains Less Than 2% of

Target Groups

VegetarianAdult (18 - 50 Years)Gluten Free

Label Claims

All OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a herbal supplement, adults take one (1) capsule with any meal, twice daily or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Precautions re: All Other

Do not exceed recommended dosage.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Precautions re: All Other

Stop use and contact a physician if adverse reactions occur.

Precautions re: Children

Keep out of reach of children.

Precautions re: All Other

Do not use if product appears to be tampered with or seal is broken.

Storage

Storage

Store at room temperature.

Formulation

Formulation re: Does NOT Contain

No added Sugar, Salt, Yeast, Preservatives or Artificial Flavors.

Formulation re: Vegetarian/Vegan

100% Vegetarian.

Formulation re: Does NOT Contain

Gluten free

Formula re: Contains

St. John's Wort Extract (Hypericum perforatum) is a perennial plant found in North America containing hypericin and used for many years as a calming herb to support mood and mental outlook.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Other Label Statements

General Statements: All Other Content

Individual results may vary.

General Statements: All Other Content

Standardized Mood & Mental Outlook Support

Seals/Symbols

Gluten free

Seals/Symbols

Guaranteed quality Laboratory tested

Manufacturer & Distributor

Manufacturer

21st Century HealthCare, Inc.

2119 S. Wilson St., Tempe, AZ, 85282, USA

Market Reference

$5.99 – $1540.00· 40 listings
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  • GNC Herbal Plus St. John's Wort Extract 300Mg

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  • Healths Harmony St John's Wort Extract

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  • Nature's Answer St John's Wort Young Flowering Tops

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  • Swanson Vitamins St. John's Wort Extract

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Where to Buy Locally

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Showing representative supplement & health retailers — search above for stores in your area.

  • BioTechUSA LOOM Bielefeld

    4.3 (66)

    Vitamin & supplements store

    Bahnhofstraße 28, 33602 Bielefeld

Research & Studies

  • St. John's wort

    HL Field, DA Monti, JM Greeson… - … International Journal of …, 2000 - journals.sagepub.com

    … As the twenty-first century begins, more patients in the United States are turning to alternative or complimentary medical treatments. Forty percent of respondents to a recent survey used …

    200022 citations
  • Polyphenol and Flavonoid Content and Antioxidant Activity of Hypericum perforatum L. (St. John's Wort) Extracts for Potential Pharmaceutical and Cosmetic …

    E Błońska-Sikora, A Zielińska, N Dobros… - Applied Sciences, 2025 - mdpi.com

    … John’s wort (Hypericum perforatum) has been used for centuries in traditional medicine owing to its high content of various bioactive metabolites and wide geographic occurrence. …

    202515 citations
  • Protective role of St. John's wort and its components hyperforin and hypericin against diabetes through inhibition of inflammatory signaling: Evidence from in …

    M Novelli, P Masiello, P Beffy, M Menegazzi - International journal of …, 2020 - mdpi.com

    … Diabetes mellitus affects 463 million people worldwide, and it is one of the fastest growing health challenges of the twenty-first century, with the number of adults living with diabetes …

    202073 citations
  • Drug interactions with St John's wort: mechanisms and clinical implications

    M Mannel - Drug safety, 2004 - Springer

    … (Hypericum perforatum) have been used for centuries in … , clinical efficacy of hydroalcoholic St John’s wort extracts at a daily … of the German Medical Association included St John’s wort …

    2004317 citations
  • A systematic review of St. John's wort for major depressive disorder

    EA Apaydin, AR Maher, R Shanman, MS Booth… - Systematic reviews, 2016 - Springer

    … of, mental health treatment, side effects of medication, and other factors cause many individuals to not seek standard treatments. For centuries, extracts of the herb St. John’s wort (…

    2016269 citations
  • St. John's wort (Hypericum perforatum)

    T Belwal, HP Devkota, MK Singh, R Sharma… - … nutritional supplements, 2019 - Elsevier

    Hypericum perforatum L. also known as St John’s wort (SJW) is an effective dietary supplement for treating various nervous system related disorders. It overcome anxiety, mild to …

    201932 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-08-23. DSLD Label ID: 205610. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.